Research Topics
| A L LeisewitzSummaryAffiliation: University of Pretoria Country: South Africa Publications
| Collaborators
|
Detail Information
Publications
Response of the splenic dendritic cell population to malaria infectionAndrew L Leisewitz
Weatherall Institute of of Molecular Medicine, and University Department of Paediatrics, John Radcliffe Hospital, University of Oxford, Oxford, UK
Infect Immun 72:4233-9. 2004..These findings show that splenic dendritic cells are actively engaged in the earliest phase of malarial infection in vivo and are likely to be critical in shaping the subsequent immune response...- BCG-malaria co-Infection has paradoxical effects on C57BL/6 and A/J mouse strainsA L Leisewitz
Department of Veterinary Tropical Diseases, Onderstepoort, South Africa
Parasite Immunol 30:1-12. 2008..A moderate TH1 response in the A/J model may have been responsible for the improved survival, and an excessive TH1 response in the C57BL/6 model may have contributed to their death... - Canine babesiosis in South Africa: more than one disease. Does this serve as a model for falciparum malaria?F Reyers
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
Ann Trop Med Parasitol 92:503-11. 1998..It is evident that the inflammatory-response disease presentation, which is similar to complicated falciparum malaria in humans, amy serve as an animal model for the disease... - The diagnosis and management of snakebite in dogs--a southern African perspectiveA L Leisewitz
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
J S Afr Vet Assoc 75:7-13. 2004..stiletto snake and other lesser adder bites. There are some important differences between the way snakebites are managed in humans and dogs... - Prognostic usefulness of blood leukocyte changes in canine parvoviral enteritisA Goddard
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J Vet Intern Med 22:309-16. 2008..Despite treatment, many dogs still die of complications related to canine parvoviral (CPV) enteritis. Effective prognostication would be beneficial in managing this disease... - Detection of a Theileria species in dogs in South AfricaP T Matjila
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
Vet Parasitol 157:34-40. 2008..in dogs for the first time in South Africa and add yet another microorganism to the growing list of haemoprotozoan parasites infecting dogs worldwide. The clinical significance of this infection in dogs is poorly resolved... - Preliminary evaluation of the BrEMA1 gene as a tool for associating babesia rossi genotypes and clinical manifestation of canine BabesiosisP T Matjila
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
J Clin Microbiol 47:3586-92. 2009..6% each), and genotype11 (12.7%). These genotypes were also the ones associated with the poorest prognosis. This preliminary finding suggests clinically important differences between the various B. rossi genotypes identified... - Molecular characterisation of Babesia gibsoni infection from a pit-bull terrier pup recently imported into South AfricaP T Matjila
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, 0110 South Africa
J S Afr Vet Assoc 78:2-5. 2007..Blood samples taken on Day 1 and Day 40 after completion of treatment were negative for B. gibsoni DNA on PCR/RLB test. The implications of a possible introduction of B. gibsoni into South Africa are discussed... - Molecular detection of tick-borne protozoal and ehrlichial infections in domestic dogs in South AfricaPaul Tshepo Matjila
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, 0110 Onderstepoort, South Africa
Vet Parasitol 155:152-7. 2008..There was also one incidental finding of a dog positive for Trypanosoma congolense. The results indicate that a wide range of tick-borne pathogens are circulating in the canine populations in South Africa... - Molecular detection of Babesia rossi and Hepatozoon sp. in African wild dogs (Lycaon pictus) in South AfricaPaul Tshepo Matjila
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, 0110 Onderstepoort, South Africa
Vet Parasitol 157:123-7. 2008..Sixteen specimens were found positive for Babesia rossi and two dogs were Hepatozoon sp. positive. It appears that these tick-borne pathogens are not widely distributed in wild dog populations... - Capillary and venous Babesia canis rossi parasitaemias and their association with outcome of infection and circulatory compromiseMarlies Böhm
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Pretoria, South Africa
Vet Parasitol 141:18-29. 2006..Despite the highly significant association between compromised circulation and higher parasitaemia, it is thought unlikely that parasite burden is the sole trigger for circulatory collapse... - Canine parvovirusAmelia Goddard
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, Pretoria 0110, South Africa
Vet Clin North Am Small Anim Pract 40:1041-53. 2010..This article reviews current knowledge about the virus, its epidemiology, clinical manifestation, diagnosis, management, and prevention... - The mixed acid-base disturbances of severe canine babesiosisA L Leisewitz
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J Vet Intern Med 15:445-52. 2001..01). Mixed metabolic and respiratory acid-base imbalances are common in severe canine babesiosis, and resemble imbalances described in canine endotoxemia and human malaria... - Systemic inflammatory response syndrome and multiple-organ damage/dysfunction in complicated canine babesiosisC Welzl
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J S Afr Vet Assoc 72:158-62. 2001.... - Chronic idiopathic intestinal pseudo-obstruction in an English bulldogE Dvir
Department of Companion Animal Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J Small Anim Pract 42:243-7. 2001..This case was presented with clinical findings consistent with visceral myopathy in humans--namely, atony and dilatation of the whole gut--but the histological findings resembled sclerosis limited to the gastrointestinal tract... - The use of liposomal amphotericin B in the management of Xylohypha bantiana mycosis in a dogA L Leisewitz
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J S Afr Vet Assoc 73:79-82. 2002.... - Canine distemper infections, with special reference to South Africa, with a review of the literatureA L Leisewitz
Department of Companion Animal Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J S Afr Vet Assoc 72:127-36. 2001..Early CNS lesions are characterised by demyelination and later lesions by perivascular round cell cuffing. Treatment is supportive... - Effect of early enteral nutrition on intestinal permeability, intestinal protein loss, and outcome in dogs with severe parvoviral enteritisAlbert J Mohr
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
J Vet Intern Med 17:791-8. 2003..The significantly decreased %L in the EEN versus NPO group might reflect improved gut barrier function, which could limit bacterial or endotoxin translocation... - A case-controlled retrospective study of the causes and implications of moderate to severe leukocytosis in dogs in South AfricaSandra M Weltan
IDEXX Pty Ltd, Cape Animal Medical Centre, Cape Town, South Africa
Vet Clin Pathol 37:164-72. 2008..Objectives: The aim of this study was to determine whether dogs with moderate to severe leukocytosis are likely to have similar results compared with age-matched control dogs...