Patrick H Dessein

Summary

Affiliation: Johannesburg Hospital
Country: South Africa

Publications

  1. ncbi The acute phase response does not fully predict the presence of insulin resistance and dyslipidemia in inflammatory arthritis
    Patrick H Dessein
    Department of Rheumatology, University of Witwatersrand, Johannesburg, South Africa
    J Rheumatol 29:462-6. 2002
  2. ncbi The need for tighter rheumatoid arthritis control in a South African public health care center
    Ahmed Solomon
    Department of Rheumatology, Johannesburg Hospital, University of the Witwatersrand, South Africa
    Semin Arthritis Rheum 35:122-31. 2005
  3. ncbi Traditional and nontraditional cardiovascular risk factors are associated with atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 32:435-42. 2005
  4. ncbi Subclinical hypothyroidism is associated with insulin resistance in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital and Milpark Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Thyroid 14:443-6. 2004
  5. ncbi High sensitivity C-reactive protein as a disease activity marker in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 31:1095-7. 2004
  6. ncbi Glucocorticoids and insulin sensitivity in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 31:867-74. 2004
  7. ncbi Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis: a pilot study
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, University of the Witwatersrand, South Africa
    Arthritis Res 4:R12. 2002
  8. ncbi Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, University of the Witwatersrand, South Africa
    Arthritis Res 4:R5. 2002
  9. ncbi Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital and Milpark Hospital, Parktown, South Africa
    Arthritis Res Ther 7:R634-43. 2005
  10. ncbi Risk factor profiles for atherosclerotic cardiovascular disease in black and other Africans with established rheumatoid arthritis
    Ahmed Solomon
    Department of Rheumatology, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa
    J Rheumatol 37:953-60. 2010

Collaborators

Detail Information

Publications21

  1. ncbi The acute phase response does not fully predict the presence of insulin resistance and dyslipidemia in inflammatory arthritis
    Patrick H Dessein
    Department of Rheumatology, University of Witwatersrand, Johannesburg, South Africa
    J Rheumatol 29:462-6. 2002
    ..The acute phase response and excess weight could fully explain the insulin resistance but only partially explain the dyslipidemia. These findings have important implications for the management of inflammatory arthritis...
  2. ncbi The need for tighter rheumatoid arthritis control in a South African public health care center
    Ahmed Solomon
    Department of Rheumatology, Johannesburg Hospital, University of the Witwatersrand, South Africa
    Semin Arthritis Rheum 35:122-31. 2005
    ..Facilities that allow for tighter disease activity control of RA are needed in South African public care centers...
  3. ncbi Traditional and nontraditional cardiovascular risk factors are associated with atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 32:435-42. 2005
    ..To determine the association between cardiovascular (CV) risk factors and atherosclerosis in patients with rheumatoid arthritis (RA)...
  4. ncbi Subclinical hypothyroidism is associated with insulin resistance in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital and Milpark Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Thyroid 14:443-6. 2004
    ..2). Subclinical hypothyroidism was commonly encountered and associated with insulin resistance and its related dyslipidemia in RA. Evaluation of thyroid function should be considered in future studies aimed at delineating CV risk in RA...
  5. ncbi High sensitivity C-reactive protein as a disease activity marker in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 31:1095-7. 2004
    ..To elucidate the potential contribution of high sensitivity C-reactive protein (hs-CRP) testing in the assessment of disease activity in rheumatoid arthritis (RA)...
  6. ncbi Glucocorticoids and insulin sensitivity in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 31:867-74. 2004
    ..To evaluate the effects of glucocorticoids on cardiovascular (CV) risk in rheumatoid arthritis (RA)...
  7. ncbi Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis: a pilot study
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, University of the Witwatersrand, South Africa
    Arthritis Res 4:R12. 2002
    ..Methotrexate use in RA may improve CVD risk through a marked suppression of the acute phase response. Dietary intervention prevented the increase in total and low-density lipoprotein cholesterol upon acute phase response suppression...
  8. ncbi Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, University of the Witwatersrand, South Africa
    Arthritis Res 4:R5. 2002
    ..The latter is only partially attributable to the acute phase response. The CRP, IS, HDL cholesterol, triglycerides and hypertension are inter-related in RA patients, whereas none of these relationships were found in OA patients...
  9. ncbi Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital and Milpark Hospital, Parktown, South Africa
    Arthritis Res Ther 7:R634-43. 2005
    ..Disease-modifying agents that effectively suppress both cytokine and rheumatoid factor production, and interventions aimed at preserving renal function may attenuate cardiovascular risk in RA...
  10. ncbi Risk factor profiles for atherosclerotic cardiovascular disease in black and other Africans with established rheumatoid arthritis
    Ahmed Solomon
    Department of Rheumatology, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa
    J Rheumatol 37:953-60. 2010
    ..Black Africans reportedly experience a distinctly low risk for atherosclerotic cardiovascular disease (CVD). We investigated whether this protection was present among Africans with established rheumatoid arthritis (RA)...
  11. ncbi Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital and Milpark Hospital, Parktown, University of Witwatersrand, Johannesburg, South Africa
    J Rheumatol 34:943-51. 2007
    ..To determine whether nontraditional risk factors increase the accuracy of predicting the presence of carotid artery plaque based on traditional cardiovascular risk factors only in patients with rheumatoid arthritis (RA)...
  12. ncbi Aminotransferases are associated with insulin resistance and atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    BMC Cardiovasc Disord 7:31. 2007
    ..We therefore explored the possibility that serum aminotransferase concentrations are as closely related to large artery disease as insulin resistance in rheumatoid arthritis (RA)...
  13. ncbi Independent role of conventional cardiovascular risk factors as predictors of C-reactive protein concentrations in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Parktown
    J Rheumatol 34:681-8. 2007
    ..We elucidated whether factors that determine systemic inflammation in the general population independently contribute to C-reactive protein (CRP) concentrations in rheumatoid arthritis (RA)...
  14. ncbi Impact of age on the independent association of adiposity with pulse-wave velocity in a population sample of African ancestry
    Olebogeng H I Majane
    Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Am J Hypertens 21:936-42. 2008
    ..We aimed to clarify whether age influences the independent relationship between adiposity and pulse-wave velocity (PWV)...
  15. ncbi Metabolic syndrome and subclinical atherosclerosis in rheumatoid arthritis
    Patrick H Dessein
    Department of Rheumatology, Johannesburg Hospital, Johannesburg, South Africa
    J Rheumatol 33:2425-32. 2006
    ..We further evaluated the clinical utility of currently recommended MetSyn definitions in the identification of RA patients with subclinical atherosclerosis...
  16. ncbi Insulin resistance and impaired beta cell function in rheumatoid arthritis
    Patrick H Dessein
    Johannesburg Hospital and Milpark Hospital, University of the Witwatersrand, Johannesburg, South Africa
    Arthritis Rheum 54:2765-75. 2006
    ..To identify factors that regulate glucose metabolism in rheumatoid arthritis (RA)...
  17. ncbi Public healthcare attendance associates with enhanced conventional and non-conventional atherosclerotic cardiovascular disease risk burdens in established rheumatoid arthritis
    P H Dessein
    Department of Rheumatology, University of the Witwatersrand and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa
    Clin Exp Rheumatol 28:230-7. 2010
    ..To assess whether public healthcare attendance associates with altered atherosclerotic cardiovascular disease risk in established rheumatoid arthritis (RA)...
  18. ncbi When is a patient with rheumatoid arthritis at risk for cardiovascular disease?
    Patrick H Dessein
    J Rheumatol 33:201-3. 2006
  19. ncbi Inflammation, insulin resistance, and aberrant lipid metabolism as cardiovascular risk factors in rheumatoid arthritis
    Patrick H Dessein
    J Rheumatol 30:1403-5. 2003
  20. ncbi Editorial: should we evaluate insulin sensitivity in rheumatoid arthritis?
    Patrick H Dessein
    Semin Arthritis Rheum 35:5-7. 2005
  21. ncbi Rational, cost effective use of investigations. Article gave unbalanced view of overuse of diagnostic tests
    Patrick H Dessein
    BMJ 325:222. 2002