Guo Jun Zhang

Summary

Country: Singapore

Publications

  1. ncbi Label-free direct detection of MiRNAs with silicon nanowire biosensors
    Guo Jun Zhang
    Institute of Microelectronics, Agency for Science, Technology and Research, 11 Science Park Road, 117685 Singapore, Singapore
    Biosens Bioelectron 24:2504-8. 2009
  2. ncbi Morpholino-functionalized silicon nanowire biosensor for sequence-specific label-free detection of DNA
    Guo Jun Zhang
    Institute of Microelectronics, Agency for Science, Technology and Research, 11 Science Park Road, Singapore
    Biosens Bioelectron 25:2447-53. 2010
  3. ncbi Highly sensitive measurements of PNA-DNA hybridization using oxide-etched silicon nanowire biosensors
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, Singapore 117685, Singapore
    Biosens Bioelectron 23:1701-7. 2008
  4. ncbi A novel approach to Au nanoparticle-based identification of DNA nanoarrays
    Guo Jun Zhang
    Institute of Biomedical Engineering and Nanotechnology Research Center, Waseda University, Waseda Tsurumaki cho, Shinjuku ku, Tokyo, Japan
    Front Biosci 12:4773-8. 2007
  5. ncbi Self-assembled monolayer-assisted silicon nanowire biosensor for detection of protein-DNA interactions in nuclear extracts from breast cancer cell
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, Singapore Science Park II, Singapore, Singapore
    Biosens Bioelectron 26:3233-9. 2011
  6. ncbi Highly sensitive and reversible silicon nanowire biosensor to study nuclear hormone receptor protein and response element DNA interactions
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, 11 Science Park Road, Singapore Science Park II, Singapore 117685, Singapore
    Biosens Bioelectron 26:365-70. 2010
  7. ncbi An integrated chip for rapid, sensitive, and multiplexed detection of cardiac biomarkers from fingerprick blood
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, 11 Science Park Road, Singapore 117685, Singapore
    Biosens Bioelectron 28:459-63. 2011
  8. ncbi DNA micropatterning on polycrystalline diamond via one-step direct amination
    Guo Jun Zhang
    Nanotechnology Research Center and Institute of Biomedical Engineering, Waseda University, Waseda Tsurumaki cho 513, Shinjuku ku, Tokyo 162 0041, Japan
    Langmuir 22:3728-34. 2006
  9. ncbi Label-free electrical detection of cardiac biomarker with complementary metal-oxide semiconductor-compatible silicon nanowire sensor arrays
    Jay Huiyi Chua
    Institute of Microelectronics, Agency for Science, Technology and Research, 11 Science Park Road, Singapore 117685
    Anal Chem 81:6266-71. 2009
  10. ncbi A 64-channel readout ASIC for nanowire biosensor array with electrical calibration scheme
    Kevin T C Chai
    Integrated Circuits and Systems Laboratory, Institute of Microelectronics, A STAR Agency of Science, Technology and Research, Singapore
    Conf Proc IEEE Eng Med Biol Soc 2010:3491-4. 2010

Collaborators

Detail Information

Publications17

  1. ncbi Label-free direct detection of MiRNAs with silicon nanowire biosensors
    Guo Jun Zhang
    Institute of Microelectronics, Agency for Science, Technology and Research, 11 Science Park Road, 117685 Singapore, Singapore
    Biosens Bioelectron 24:2504-8. 2009
    ..This approach paves a way for label-free, early detection of miRNA as a biomarker in cancer diagnostics with very high sensitivity and good specificity...
  2. ncbi Morpholino-functionalized silicon nanowire biosensor for sequence-specific label-free detection of DNA
    Guo Jun Zhang
    Institute of Microelectronics, Agency for Science, Technology and Research, 11 Science Park Road, Singapore
    Biosens Bioelectron 25:2447-53. 2010
    ..The Morpholino-functionalized SiNWs show a novel biosensor for label-free and direct detection of DNA with good selectivity, and a promising application in gene expression...
  3. ncbi Highly sensitive measurements of PNA-DNA hybridization using oxide-etched silicon nanowire biosensors
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, Singapore 117685, Singapore
    Biosens Bioelectron 23:1701-7. 2008
    ..Among several efforts being made to improve detection sensitivity, this work addresses one significant issue regarding surface functionalization which enables highly sensitive biomolecular sensing with SiNWs...
  4. ncbi A novel approach to Au nanoparticle-based identification of DNA nanoarrays
    Guo Jun Zhang
    Institute of Biomedical Engineering and Nanotechnology Research Center, Waseda University, Waseda Tsurumaki cho, Shinjuku ku, Tokyo, Japan
    Front Biosci 12:4773-8. 2007
    ..On the basis of fluorescent detection, an alternative method has been developed for detection of DNA nanostructures, which will benefit the development of DNA chips...
  5. ncbi Self-assembled monolayer-assisted silicon nanowire biosensor for detection of protein-DNA interactions in nuclear extracts from breast cancer cell
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, Singapore Science Park II, Singapore, Singapore
    Biosens Bioelectron 26:3233-9. 2011
    ..The SAM-assisted SiNW biosensor, as a label-free and highly sensitive tool, shows a potential in studying protein-DNA interactions...
  6. ncbi Highly sensitive and reversible silicon nanowire biosensor to study nuclear hormone receptor protein and response element DNA interactions
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, 11 Science Park Road, Singapore Science Park II, Singapore 117685, Singapore
    Biosens Bioelectron 26:365-70. 2010
    ..Through the study, we have established the SiNW biosensor as a promising method in providing comprehensive study for hormone receptor-response element interactions...
  7. ncbi An integrated chip for rapid, sensitive, and multiplexed detection of cardiac biomarkers from fingerprick blood
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, 11 Science Park Road, Singapore 117685, Singapore
    Biosens Bioelectron 28:459-63. 2011
    ..The integrated chip is able to attain a low detection limit of 1 pg/ml for the three cardiac biomarkers from 2 ?l blood in 45 min...
  8. ncbi DNA micropatterning on polycrystalline diamond via one-step direct amination
    Guo Jun Zhang
    Nanotechnology Research Center and Institute of Biomedical Engineering, Waseda University, Waseda Tsurumaki cho 513, Shinjuku ku, Tokyo 162 0041, Japan
    Langmuir 22:3728-34. 2006
    ..The influence of a different amination time on fluorescence intensity was compared. Different terminations as passivated layers were investigated, and as a result, fluorine termination points to the greatest signal-to-noise ratio...
  9. ncbi Label-free electrical detection of cardiac biomarker with complementary metal-oxide semiconductor-compatible silicon nanowire sensor arrays
    Jay Huiyi Chua
    Institute of Microelectronics, Agency for Science, Technology and Research, 11 Science Park Road, Singapore 117685
    Anal Chem 81:6266-71. 2009
    ....
  10. ncbi A 64-channel readout ASIC for nanowire biosensor array with electrical calibration scheme
    Kevin T C Chai
    Integrated Circuits and Systems Laboratory, Institute of Microelectronics, A STAR Agency of Science, Technology and Research, Singapore
    Conf Proc IEEE Eng Med Biol Soc 2010:3491-4. 2010
    ..The experimental results show that the proposed calibration technique improved the sensitivity by 2 to 10 times and reduced the variation between dataset by 9 times...
  11. ncbi Production of nanopatterns by a combination of electron beam lithography and a self-assembled monolayer for an antibody nanoarray
    Guo Jun Zhang
    Institute of Biomedical Engineering and Nanotechnology Research Center, Waseda University, Waseda Tsurumaki cho 513, Shinjuku ku, Tokyo 162 0041, Japan
    J Nanosci Nanotechnol 7:410-7. 2007
    ..The technique enables the realization of high-throughput protein nanoscale arrays with high specificity...
  12. ncbi Silicon nanowire biosensor for ultrasensitive and label-free direct detection of miRNAs
    Guo Jun Zhang
    A STAR Agency for Science, Technology and Research, Institute of Microelectronics, Singapore, Singapore
    Methods Mol Biol 676:111-21. 2011
    ..The developed detection method shows potential applications in label-free, early detection of miRNA as a biomarker in cancer diagnostics with very high sensitivity and good specificity...
  13. ncbi Multiplexed detection of cardiac biomarkers in serum with nanowire arrays using readout ASIC
    Guo Jun Zhang
    Institute of Microelectronics, A STAR Agency for Science, Technology and Research, 11 Science Park Road, Singapore 117685, Singapore School of Laboratory Medicine, Hubei University of Chinese Medicine, 1 Huangjia Lake West Road, Wuhan 430065, China
    Biosens Bioelectron 35:218-23. 2012
    ....
  14. ncbi Characterization of DNA hybridization on partially aminated diamond by aromatic compounds
    Jung-Hoon Yang
    School of Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan
    Langmuir 22:11245-50. 2006
    ..The hybridization intensities determined by epifluorescence microscopy were compared and analyzed...
  15. ncbi Nanoscale patterning of protein using electron beam lithography of organosilane self-assembled monolayers
    Guo-Jun Zhang
    Nanotechnology Research Center and Institute of Biomedical Engineering, Waseda University, Waseda Tsurumaki-cho 513, Shinjuku-ku, Tokyo 162-0041, Japan
    Small 1:833-7. 2005
  16. ncbi Microstructured arrays with pre-synthesized capture probes for DNA detection based on metal nanoparticles and silver enhancement
    Guo-Jun Zhang
    Institute for Physical High Technology, PO Box 100239, 07702 Jena, Germany
    J Fluoresc 14:369-75. 2004
    ..The optical absorption signal is improved by a silver enhancement step. Experiments demonstrated the specificity and the concentration-dependency of the signal...
  17. ncbi [Development and clinical application of the tractor for the fracture reduction]
    Guo-Jun Zhang
    The People's Hospital, Tai Gu County, Shan Xi Province
    Zhongguo Yi Liao Qi Xie Za Zhi 26:275-6, 278. 2002
    ..This paper expounds how the tractor for the fracture reduction works. The clinical results show that the traction apparatus is a labour-saving and time-saving orthopedic device with simple operation and few suffering to patients...