Research Topics
| Louis TongSummaryGrants: Publications
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Detail Information
Publications
Aspirin and dry eye?Louis Tong
Ophthalmology 116:167-167.e1. 2009
Red-green colour blindness in Singaporean childrenAudrey Chia
Singapore Eye Research Institute, Singapore
Clin Experiment Ophthalmol 36:464-7. 2008..Various studies suggest that, worldwide, 2-8% of men are afflicted with this condition. The purpose of this study is to determine the prevalence of red-green colour blindness in Singaporean schoolchildren...
Calcium-binding S100 protein expression in pterygiumAndri K Riau
Singapore Eye Research Institute, Singapore
Mol Vis 15:335-42. 2009..The aim of this study was to investigate the presence of various S100 proteins in pterygium compared to normal conjunctiva...
Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay eye studyLaurence Shen Lim
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
Invest Ophthalmol Vis Sci 51:103-9. 2010..To examine the distribution and systemic determinants of ocular biometry as measured using partial laser interferometry in an adult Asian population...
Direct costs of myopia in SingaporeM C C Lim
Department of Ophthalmology, Singapore National Eye Centre, Singapore, Singapore
Eye (Lond) 23:1086-9. 2009..To estimate the direct costs of myopia in Singapore children...
Corneal biomechanics, thickness and optic disc morphology in children with optic disc tiltL Lim
Singapore Eye Research Institute, Singapore
Br J Ophthalmol 92:1461-6. 2008....
Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression dataLouis Tong
Singapore Eye Research Institute SERI, Singapore National Eye Center, Singapore
BMC Med Genomics 2:14. 2009..For patients demonstrating a profile of 'recurrence', it may be necessary to manage as a poorer prognostic case and perhaps, more adjunctive treatment after resection of the primary lesion...
Refractive error and monochromatic aberrations in Singaporean childrenAndrew Carkeet
Singapore National Eye Centre, Singapore Eye Research Institute, Level 6, 11 Third Hospital Avenue, 168751 Singapore
Vision Res 42:1809-24. 2002..e. of posterior cornea and crystalline lens) did vary significantly with refractive error and race. Our results do not provide any evidence for aberration-driven form-deprivation as a major mechanism of myopia development...
Heidelberg retinal tomography of optic disc and nerve fiber layer in singapore children: variations with disc tilt and refractive errorLouis Tong
Singapore National Eye Center, Singapore
Invest Ophthalmol Vis Sci 48:4939-44. 2007....
Corneal thickness determination and correlates in Singaporean schoolchildrenLouis Tong
Singapore National Eye Center, Singapore
Invest Ophthalmol Vis Sci 45:4004-9. 2004..To determine the central cornea thickness (CCT) in Singaporean children and to examine the possible relationship between intraocular pressure (IOP) and other biometric factors and CCT...
Screening for myopia and refractive errors using LogMAR visual acuity by optometrists and a simplified visual acuity chart by nursesLouis Tong
Singapore National Eye Center, Singapore
Optom Vis Sci 81:684-91. 2004..A secondary aim is to estimate the best cutoff values for the detection of refractive errors using these two methods...
A questionnaire-based assessment of symptoms associated with tear film dysfunction and lid margin disease in an Asian populationLouis Tong
Singapore National Eye Center, Singapore
Ophthalmic Epidemiol 16:31-7. 2009..To study the prevalence, associated factors and impact of symptomatic dry eye in an Asian population...
Anisometropia in Singapore school childrenLouis Tong
Singapore National Eye Center, Singapore, Singapore
Am J Ophthalmol 137:474-9. 2004..To report the prevalence rates of anisometropia in a school population and determine the relative contribution of refractive power and axial length to the measured anisometropia...
Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomicsLei Zhou
Singapore Eye Research Institute, Singapore, Singapore
J Proteome Res 8:4889-905. 2009..This study demonstrated that iTRAQ technology combined with 2D-nanoLC-nanoESI-MS/MS quantitative proteomics is a powerful tool for biomarker discovery...
Phospholipase D in the human ocular surface and in pterygiumLouis Tong
Singapore National Eye Center, Third Hospital Avenue, Singapore
Cornea 27:693-8. 2008..We aimed to study the presence of PLD subtypes in native ocular surface tissue and pterygium...
Impact of symptomatic dry eye on vision-related daily activities: the Singapore Malay Eye StudyL Tong
Department of Ophthalmology, Singapore National Eye Center, Singapore, Singapore
Eye (Lond) 24:1486-91. 2010..To examine the impact of symptomatic dry eye on vision-related daily activities...
Comparison of gene expression profiles of conjunctival cell lines with primary cultured conjunctival epithelial cells and human conjunctival tissueLouis Tong
Singapore National Eye Center, Singapore
Gene Expr 14:265-78. 2009....
Screening for meibomian gland disease: its relation to dry eye subtypes and symptoms in a tertiary referral clinic in singaporeLouis Tong
Singapore National Eye Center, Singapore
Invest Ophthalmol Vis Sci 51:3449-54. 2010..These findings facilitate better understanding of the meibomian gland's contribution to multifactorial dry eye syndrome, apart from routine conventional tests performed in clinics...
Atropine for the treatment of childhood myopia: effect on myopia progression after cessation of atropineLouis Tong
Singapore National Eye Center, Singapore
Ophthalmology 116:572-9. 2009..The aim of this study was to assess the effect on myopia progression after cessation of topical atropine treatment...
Prevalence and risk factors of undercorrected refractive errors among Singaporean Malay adults: the Singapore Malay Eye StudyMohamad Rosman
Singapore National Eye Center, Singapore
Invest Ophthalmol Vis Sci 50:3621-8. 2009..To describe the prevalence and the risk factors of undercorrected refractive error in an adult urban Malay population...
Longitudinal study of anisometropia in Singaporean school childrenLouis Tong
Singapore National Eye Center, National University of Singapore, Singapore
Invest Ophthalmol Vis Sci 47:3247-52. 2006....
Cornea biomechanical characteristics and their correlates with refractive error in Singaporean childrenLaurence Lim
Singapore Eye Research Institute, Singapore
Invest Ophthalmol Vis Sci 49:3852-7. 2008..To determine corneal biomechanical parameters measured with the Reichert Ocular Response Analyser (ORA) in Singaporean children, and to assess their possible correlations with refractive error and biometry...
Sensitivity and specificity of visual acuity screening for refractive errors in school childrenLouis Tong
Singapore National Eye Centre, Singapore
Optom Vis Sci 79:650-7. 2002..To examine the optimal cutoff point for the use of the visual acuity test to screen for refractive errors in schoolchildren...
Agreement between Scheimpflug photography and A-scan ultrasonography in anterior segment ocular measurements in childrenLouis Tong
Singapore National Eye Centre, Singapore
Optom Vis Sci 80:529-34. 2003..The purpose of this study was to examine the agreement in anterior chamber length and lens thickness measurements between A-scan ultrasonography and Scheimpflug photography...
Optic disk and retinal characteristics in myopic childrenLouis Tong
Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751
Am J Ophthalmol 138:160-2. 2004..To examine the baseline retina and optic disk characteristics in children...
Incidence and progression of myopia in Singaporean school childrenSeang Mei Saw
Department of Community, Occupational and Family Medicine, National University of Singapore
Invest Ophthalmol Vis Sci 46:51-7. 2005..To determine the incidence and progression rates of myopia in young Singaporean children...
Expression and regulation of cornified envelope proteins in human corneal epitheliumLouis Tong
Ocular Surface Center, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas 77030, USA
Invest Ophthalmol Vis Sci 47:1938-46. 2006....
Atropine for the treatment of childhood myopiaWei Han Chua
Singapore National Eye Centre, Singapore
Ophthalmology 113:2285-91. 2006..To evaluate the efficacy and safety of topical atropine, a nonselective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in Asian children...
Transglutaminase participates in UVB-induced cell death pathways in human corneal epithelial cellsLouis Tong
Ocular Surface Center, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas 77030, USA
Invest Ophthalmol Vis Sci 47:4295-301. 2006..CONCLUSIONS: Transglutaminase enzymatic activity is involved in corneal epithelial cell death after UVB and appears to participate in two steps regulating this process, clustering of TNF receptor-I and caspase-3 activation...
Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPKZhuo Chen
Department of Ophthalmology, The Ocular Surface Center, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA
Invest Ophthalmol Vis Sci 49:539-49. 2008....
A multiple regression approach to study optical components of myopia in Singapore school childrenLouis Tong
Singapore Eye Research Institute and Singapore National Eye Centre
Ophthalmic Physiol Opt 22:32-7. 2002..We perform a study to assess the association of the optical components of the eye contributing to the degree of myopia by building a statistical model which can better assess the individual effects of each optical component...
