Phillippe Taupin

Summary

Affiliation: National University of Singapore
Country: Singapore

Publications

  1. ncbi Stroke-induced neurogenesis: physiopathology and mechanisms
    Philippe Taupin
    National Neuroscience Institute, Singapore, National University of Singapore, Nanyang Technological University, Singapore
    Curr Neurovasc Res 3:67-72. 2006
  2. ncbi Protocols for studying adult neurogenesis: insights and recent developments
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore and Nanyang Technological University, Singapore
    Regen Med 2:51-62. 2007
  3. ncbi Processing scarce biological samples for light and transmission electron microscopy
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Eur J Histochem 52:135-9. 2008
  4. ncbi BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Brain Res Rev 53:198-214. 2007
  5. ncbi Neural progenitor and stem cells in the adult central nervous system
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore
    Ann Acad Med Singapore 35:814-20. 2006
  6. ncbi Autologous transplantation in the central nervous system
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore and Nanyang Technological University, Singapore
    Indian J Med Res 124:613-8. 2006
  7. ncbi Adult neural stem cells, neurogenic niches, and cellular therapy
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Stem Cell Rev 2:213-9. 2006
  8. ncbi Stem cells engineering for cell-based therapy
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    J Neural Eng 4:R59-63. 2007
  9. ncbi Therapeutic potential of adult neural stem cells
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Recent Pat CNS Drug Discov 1:299-303. 2006
  10. ncbi Adult neurogenesis pharmacology in neurological diseases and disorders
    Philippe Taupin
    National Neuroscience Institute National University of Singapore Nanyang Technological University, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    Expert Rev Neurother 8:311-20. 2008

Detail Information

Publications20

  1. ncbi Stroke-induced neurogenesis: physiopathology and mechanisms
    Philippe Taupin
    National Neuroscience Institute, Singapore, National University of Singapore, Nanyang Technological University, Singapore
    Curr Neurovasc Res 3:67-72. 2006
    ..In this manuscript, we will review the studies on adult neurogenesis in cerebral strokes, discuss the contribution of adult neurogenesis to the physiopathology of strokes, and its underlying mechanisms...
  2. ncbi Protocols for studying adult neurogenesis: insights and recent developments
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore and Nanyang Technological University, Singapore
    Regen Med 2:51-62. 2007
    ..I will review these techniques, and discuss their implications for the field of adult neurogenesis...
  3. ncbi Processing scarce biological samples for light and transmission electron microscopy
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Eur J Histochem 52:135-9. 2008
    ..This preparation provides a simple and reproducible technique to process biological materials, present in limited quantities that can not be amplified, for light and transmission electron microscopy...
  4. ncbi BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Brain Res Rev 53:198-214. 2007
    ....
  5. ncbi Neural progenitor and stem cells in the adult central nervous system
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore
    Ann Acad Med Singapore 35:814-20. 2006
    ..We will discuss their contribution and significance to CNS pathophysiology, and for cellular therapy...
  6. ncbi Autologous transplantation in the central nervous system
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore and Nanyang Technological University, Singapore
    Indian J Med Res 124:613-8. 2006
    ....
  7. ncbi Adult neural stem cells, neurogenic niches, and cellular therapy
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Stem Cell Rev 2:213-9. 2006
    ..Hence, neurogenic niches may not only hold the key to our understanding of neurogenesis in the adult brain, but also of the developmental potential of adult NSCs, and their potential for cellular therapy...
  8. ncbi Stem cells engineering for cell-based therapy
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    J Neural Eng 4:R59-63. 2007
    ..In this review, I will review, in two examples, how investigators are applying cell engineering to stem cell biology to circumvent stem cells' ethical and political constraints and bolster stem cell research and therapy...
  9. ncbi Therapeutic potential of adult neural stem cells
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Recent Pat CNS Drug Discov 1:299-303. 2006
    ..In this manuscript, we will review the recent developments in adult neurogenesis and NSCs, and patent applications filed in relation to discoveries made in this new field of research...
  10. ncbi Adult neurogenesis pharmacology in neurological diseases and disorders
    Philippe Taupin
    National Neuroscience Institute National University of Singapore Nanyang Technological University, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    Expert Rev Neurother 8:311-20. 2008
    ..This shows that adult neurogenesis is not only important for our understanding of development and therapy, but also for the physiopathology of the CNS and its pharmacology...
  11. ncbi Adult neurogenesis in mammals
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore, 11 Jalan Tan Tock Seng, Singapore
    Curr Opin Mol Ther 8:345-51. 2006
    ..Taken together, these findings suggest that new neuronal cells may be involved in processes such as homeostasis of brain tissue, regeneration, plasticity, and neuroadaptation...
  12. ncbi Neurogenesis in the adult central nervous system
    Philippe Taupin
    National Neuroscience Institute, Singapore, 11 Jalan Tan Tock Seng, Singapore 308433
    C R Biol 329:465-75. 2006
    ..Thus, not only neurogenesis contributes to reshaping the adult brain, it will ultimately lead us to redefine our knowledge and understanding of the nervous system...
  13. ncbi Derivation of embryonic stem cells for cellular therapy: challenges and new strategies
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Med Sci Monit 12:RA75-8. 2006
    ..In this manuscript, we will review and discuss these developments that may unlock ES cell research and therapy...
  14. ncbi HuCNS-SC (StemCells)
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore, 11 Jalan Tan Tock Seng, Singapore
    Curr Opin Mol Ther 8:156-63. 2006
    ..A phase I trial of HuCNS-SC for infantile and late-infantile NCL has been initiated, following the March 2006 U.S. Food and Drug Administration approval of StemCells' investigational new drug application...
  15. ncbi OTI-010 Osiris Therapeutics/JCR Pharmaceuticals
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore, Singapore
    Curr Opin Investig Drugs 7:473-81. 2006
    ..Phase II clinical trials in acute gastrointestinal GVHD and in adult and pediatric patients with treatment-refractory severe GVHD are currently underway...
  16. ncbi Drug evaluation: ADA-transduced hematopoietic stem cell therapy for ADA-SCID
    Phillippe Taupin
    National Neuroscience Institute, National University of Singapore, Nanyang Technological University, 11 Jalan Tan Tock Seng, 308433 Singapore
    IDrugs 9:423-30. 2006
    ....
  17. ncbi The therapeutic potential of adult neural stem cells
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore, 11 Jalan Tan Tock Seng, 308433 Singapore
    Curr Opin Mol Ther 8:225-31. 2006
    ....
  18. ncbi Adult neurogenesis and neuroplasticity
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Restor Neurol Neurosci 24:9-15. 2006
    ..Thus, injury-induced neurogenesis may contribute to the recovery and plasticity of the CNS...
  19. ncbi [Neurogenesis in the pathologies of the nervous system]
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, National University of Singapore, Nanyang Technological University, 308433 Singapore
    Med Sci (Paris) 21:711-4. 2005
    ..In this manuscript, we will review the studies on neurogenesis in the pathologies of the nervous system...
  20. ncbi Adult neurogenesis in the mammalian central nervous system: functionality and potential clinical interest
    Philippe Taupin
    National Neuroscience Institute, Singapore, Singapore
    Med Sci Monit 11:RA247-252. 2005
    ..Neural stem cells also hold the promise to cure a broad range of neurological diseases and injuries. Cell therapeutic interventions may involve both cell transplantation and the stimulation of endogenous neural progenitor cells...