Research Topics
| Anil KishenSummaryAffiliation: National University of Singapore Country: Singapore Publications
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Detail Information
Publications
Investigations on the dynamics of water in the macrostructural dentineAnil Kishen
Biophotonics Laboratory, Faculty of Dentistry, National University of Singapore, Singapore 119074, Republic of Singapore
J Biomed Opt 11:054018. 2006..These experiments highlighted that the free water in the dentine surface, porosities and tubules are lost rapidly and constitute the major water lost when dehydrated at 21 degrees C...- Enterococcus faecalis-mediated biomineralized biofilm formation on root canal dentine in vitroA Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
J Biomed Mater Res A 77:406-15. 2006..This ability of E. faecalis to form such calcified biofilm on root canal dentine may be a factor that contributes to their persistence after endodontic treatment... - Influence of irrigation regimens on the adherence of Enterococcus faecalis to root canal dentinAnil Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
J Endod 34:850-4. 2008..faecalis cells. This study highlighted that chemicals that alter the physicochemical properties of dentin will influence the nature of adherence, adhesion force, and subsequent biofilm formation of E. faecalis to dentin... - Photomechanical investigations on the stress-strain relationship in dentine macrostructureA Kishen
National University of Singapore, Department of Restorative Dentistry, Faculty of Dentistry, Singapore 119704, Republic of Singapore
J Biomed Opt 10:034010. 2005..It is apparent from these observations that complex organization of material properties facilitated distinct strain gradients in dentine structure during mechanical functions... - Periapical biomechanics and the role of cyclic biting force in apical retrograde fluid movementA Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
Int Endod J 38:597-603. 2005..To investigate the stress distribution pattern in the periapical region caused by biting forces and to study the role of cyclic biting loads on periapical fluid movement... - Digital moiré interferometric investigations on the deformation gradients of enamel and dentine: an insight into non-carious cervical lesionsA Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore, Singapore 119074
J Dent 34:12-8. 2006..The objective of this study was to evaluate the biomechanical basis of non-carious cervical lesions by examining the patterns of deformation (strain) in the enamel and dentine... - Experimental investigation on the role of water in the mechanical behavior of structural dentineA Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119704
J Biomed Mater Res A 73:192-200. 2005..This experiment highlights hydration-induced, distinct in-plane strain gradients in the directions perpendicular and parallel to the dentinal tubules in the dentine structure... - Chairside sensor for rapid monitoring of Enterococcus faecalis activityA Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore
J Endod 30:872-5. 2004..9387) with the formation of colony-forming units. Optical spectroscopy-based sensing systems can pave the way for rapid, nonlaboratory-based approaches to monitor microbial status quantitatively and qualitatively from clinical samples... - Stress-strain response in human dentine: rethinking fracture predilection in postcore restored teethAnil Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore 119074
Dent Traumatol 20:90-100. 2004..During post-endodontic restoration with increase in loss of inner dentine, the fracture resistance factor contributed by the inner dentine is compromised, and this in turn predisposes the tooth to catastrophic fracture... - An investigation on the antibacterial and antibiofilm efficacy of cationic nanoparticulates for root canal disinfectionAnil Kishen
Department of Restorative Dentistry, National University of Singapore, Singapore
J Endod 34:1515-20. 2008..There was a significant reduction in the adherence of Enterococcus faecalis to nanoparticulates-treated dentin (p < 0.05). These experiments highlighted the potential advantage of nanoparticulates in root canal disinfection... - Hydromechanics in dentine: role of dentinal tubules and hydrostatic pressure on mechanical stress-strain distributionA Kishen
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Republic of Singapore
Dent Mater 23:1296-306. 2007..This investigation is to understand the role of free water in the dentinal tubules on the mechanical integrity of bulk dentine... - Monitoring bacterial-demineralization of human dentine by electrochemical impedance spectroscopyZhang Xu
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, 5 Lower Kent Ridge Road, 119074 Singapore, Singapore
J Dent 38:138-48. 2010.... - Augmenting the antibiofilm efficacy of advanced noninvasive light activated disinfection with emulsified oxidizer and oxygen carrierSaji George
Department of Restorative Dentistry, National University of Singapore, National University Hospital, Republic of Singapore
J Endod 34:1119-23. 2008..This modified photosensitizer formulation will have potential advantages in endodontic disinfection... - Role of efflux pump inhibitors on the antibiofilm efficacy of calcium hydroxide, chitosan nanoparticles, and light-activated disinfectionMegha Upadya
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
J Endod 37:1422-6. 2011..The purpose of this study was to evaluate the role of efflux pumps in altering the susceptibility of Enterococcus faecalis biofilms to calcium hydroxide (Ca(OH)(2)), chitosan nanoparticles, and light-activated disinfection (LAD)... - Effect of tissue fluids on hydrophobicity and adherence of Enterococcus faecalis to dentinSaji George
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore, Republic of Singapore
J Endod 33:1421-5. 2007..faecalis to dentin. The findings from this study indicated that the coronal leakage of saliva and the physiologic state of microbes might play an important role in the adherence and biofilm formation of bacteria to root canal dentin... - Influence of photosensitizer solvent on the mechanisms of photoactivated killing of Enterococcus faecalisSaji George
Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
Photochem Photobiol 84:734-40. 2008..The findings from our study showed that PDT destroyed the functional integrity of cell wall, DNA and membrane proteins of E. faecalis. The degrees of damage on these targets were influenced by the photosensitizer solvent used during PDT... - Biomimetic deposition of calcium phosphate minerals on the surface of partially demineralized dentine modified with phosphorylated chitosanZhang Xu
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore 119074, Singapore
J Biomed Mater Res B Appl Biomater 98:150-9. 2011..Thus, P-chi can facilitate surface remineralization of dentine and thereby could find application in the minimally invasive management of dentine caries and dentine hypersensitivity... - Influence of endodontic chemical treatment on Enterococcus faecalis adherence to collagen studied with laser scanning confocal microscopy and optical tweezers: a preliminary studyCheePeng Sum
National University of Singapore, Department of Restorative Dentistry, Faculty of Dentistry, 5 Lower Kent Ridge Rd, Singapore 119074
J Biomed Opt 13:044017. 2008..The findings from the present study suggests that the presence of calcium hydroxide increased the adhesion force and adherence of E. faecalis to type-I collagen... - Immunogenic potential of Enterococcus faecalis biofilm under simulated growth conditionsShibi Mathew
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
J Endod 36:832-6. 2010.... - What we leave behind in root canals after endodontic treatment: some issues and concernsChee Peng Sum
Department of Restorative Dentistry, National University of Singapore
Aust Endod J 31:94-100. 2005..This information will enable clinicians to use the beneficial effects of these chemicals, while necessary steps are considered to reduce their harmful effects on dentine substrate... - Delivery of antibacterial nanoparticles into dentinal tubules using high-intensity focused ultrasoundAnnie Shrestha
Department of Restorative Dentistry, National University of Singapore, Singapore
J Endod 35:1028-33. 2009..This study aims to investigate the efficacy of collapsing cavitation bubbles to deliver antibacterial nanoparticles into dentinal tubules to improve root canal disinfection... - Monitoring acid-demineralization of human dentine by electrochemical impedance spectroscopy (EIS)Zhang Xu
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore
J Dent 36:1005-12. 2008.... - Comparison of the response of human embryonic stem cells and their differentiated progenies to oxidative stressSaji George
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
Photomed Laser Surg 27:669-74. 2009..To investigate effects of oxidative stress on human embryonic stem cells (hESC) and their spontaneously differentiated fibroblastic progenies (at passage 5)... - Uptake pathways of anionic and cationic photosensitizers into bacteriaSaji George
Faculty of Dentistry, National University of Singapore, Republic of Singapore
Photochem Photobiol Sci 8:788-95. 2009.... - Photophysical, photochemical, and photobiological characterization of methylene blue formulations for light-activated root canal disinfectionSaji George
National University of Singapore, Faculty of Dentistry, Biophotonics Microbiology Laboratory, Singapore, Singapore 119074
J Biomed Opt 12:034029. 2007..The MIX-based photosensitization medium in combination with dual-stage approach demonstrates thorough disinfection of the root canal with bacterial biofilms. This method will have potential application for root canal disinfection... - Light activated disinfection: an alternative endodontic disinfection strategyZ Lim
Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
Aust Dent J 54:108-14. 2009..This study tested the efficacy of this improved light activated disinfection on ex vivo biofilms of Enterococcus faecalis at two different stages of maturation... - The role of environmental changes on monospecies biofilm formation on root canal wall by Enterococcus faecalisS George
Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore
J Endod 31:867-72. 2005..001). This study demonstrated distinct ultrastructural and physiochemical properties of the biofilms formed and dentinal tubular penetration of E. faecalis under different conditions... - Advanced noninvasive light-activated disinfection: assessment of cytotoxicity on fibroblast versus antimicrobial activity against Enterococcus faecalisSaji George
Department of Restorative Dentistry, National University of Singapore, Singapore, Republic of Singapore
J Endod 33:599-602. 2007..An irradiation dose producing 97.7% bacterial killing showed only 30% fibroblast dysfunction. This study indicated that ANILAD produced an insignificant effect on mammalian cells... - Mechanism of strength increase for a hydrothermal porcelainJason A Griggs
Department of Biomaterials Science, Baylor College of Dentistry, TAMUS HSC, 3302 Gaston Avenue, Dallas, TX 75246, USA
Dent Mater 19:625-31. 2003.... - Effect of hydrolyzed surface layer on the cytotoxicity and chemical resistance of a low fusing porcelainJason A Griggs
Department of Biomaterials Science, Baylor College of Dentistry, TAMUS HSC, 3302 Gaston Avenue, Dallas, TX 75246, USA
Dent Mater 19:353-8. 2003.... - Determination of bacterial activity by use of an evanescent-wave fiber-optic sensorM Shelly John
School of Mechanical and Production Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798
Appl Opt 41:7334-8. 2002..The acidogenic profile of Streptococcus mutans is estimated by use of evanescent-waveabsorption spectra at various levels of bacterial activity...