Sebastian Maurer-Stroh

Summary

Country: Singapore

Publications

  1. ncbi Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins
    Wing Cheong Wong
    Bioinformatics Institute, Agency for Science, Technology and Research, Matrix, Singapore
    Biol Direct 6:57. 2011
  2. ncbi Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2
    Vachiranee Limviphuvadh
    Bioinformatics Institute, Agency for Science, Technology and Research, 30 Biopolis Street, 07 01 Matrix, 138671 Singapore
    BMC Biochem 11:39. 2010
  3. ncbi Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites
    Sebastian Maurer-Stroh
    Biomolecular Function Discovery Division, Bioinformatics Institute BII, Agency for Science Technology and Research A STAR, Singapore
    Biol Direct 4:18; discussion 18. 2009
  4. ncbi The Janus-faced E-values of HMMER2: extreme value distribution or logistic function?
    Wing Cheong Wong
    Bioinformatics Institute BII, Agency for Science, Technology and Research A STAR, 30 Biopolis Street 07 01, Matrix, Singapore 138671, Singapore
    J Bioinform Comput Biol 9:179-206. 2011
  5. ncbi More than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology
    Wing Cheong Wong
    Bioinformatics Institute BII, Agency for Science, Technology and Research A STAR, Singapore
    PLoS Comput Biol 6:e1000867. 2010
  6. ncbi All that glitters is not gold--founder effects complicate associations of flu mutations to disease severity
    Raphael T C Lee
    Bioinformatics Institute BII, Agency for Science Technology and Research A STAR, 30 Biopolis Street, 07 01, Matrix 138671, Singapore
    Virol J 7:297. 2010
  7. ncbi A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus
    Sebastian Maurer-Stroh
    Bioinformatics Institute BII, ASTAR Singapore Bioinformatics Institute BII, A STAR Bioinformatics Institute BII A STAR Singapore and National Public Health Laboratory, Ministry of Health, Singapore
    PLoS Curr 2:RRN1162. 2010
  8. ncbi Structural insight into the glycosylphosphatidylinositol transamidase subunits PIG-K and PIG-S from yeast
    Yew Kwang Toh
    Bioinformatics Institute, BII, Agency for Science, Technology and Research A STAR, Singapore, Singapore
    J Struct Biol 173:271-81. 2011
  9. ncbi Is LGI2 the candidate gene for partial epilepsy with pericentral spikes?
    Vachiranee Limviphuvadh
    Bioinformatics Institute BII, Agency for Science, Technology and Research A STAR, 30 Biopolis Street, Singapore 138671, Singapore
    J Bioinform Comput Biol 8:117-27. 2010
  10. ncbi Parameterization of disorder predictors for large-scale applications requiring high specificity by using an extended benchmark dataset
    Fernanda L Sirota
    Biomolecular Function Discovery Division, Bioinformatics Institute BII, Agency for Science Technology and Research A STAR, Matrix, Singapore
    BMC Genomics 11:S15. 2010

Collaborators

Detail Information

Publications10

  1. ncbi Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins
    Wing Cheong Wong
    Bioinformatics Institute, Agency for Science, Technology and Research, Matrix, Singapore
    Biol Direct 6:57. 2011
    ..Simple, quantitative criteria are desirable for identifying transmembrane helices (TMs) that must be included into or should be excluded from start sequence segments in similarity searches aimed at finding distant homologues...
  2. ncbi Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2
    Vachiranee Limviphuvadh
    Bioinformatics Institute, Agency for Science, Technology and Research, 30 Biopolis Street, 07 01 Matrix, 138671 Singapore
    BMC Biochem 11:39. 2010
    ....
  3. ncbi Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites
    Sebastian Maurer-Stroh
    Biomolecular Function Discovery Division, Bioinformatics Institute BII, Agency for Science Technology and Research A STAR, Singapore
    Biol Direct 4:18; discussion 18. 2009
    ..REVIEWERS: This article was reviewed by Sandor Pongor and L. Aravind...
  4. ncbi The Janus-faced E-values of HMMER2: extreme value distribution or logistic function?
    Wing Cheong Wong
    Bioinformatics Institute BII, Agency for Science, Technology and Research A STAR, 30 Biopolis Street 07 01, Matrix, Singapore 138671, Singapore
    J Bioinform Comput Biol 9:179-206. 2011
    ..1 when the EVD provides an E-value > 0.1. We provide examples of false annotations and critically discuss the appropriateness of a logistic function as alternative to the EVD...
  5. ncbi More than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology
    Wing Cheong Wong
    Bioinformatics Institute BII, Agency for Science, Technology and Research A STAR, Singapore
    PLoS Comput Biol 6:e1000867. 2010
    ..We suggest a workflow of flagging problematic hits arising from SP/TM-containing models for critical reconsideration by annotation users...
  6. ncbi All that glitters is not gold--founder effects complicate associations of flu mutations to disease severity
    Raphael T C Lee
    Bioinformatics Institute BII, Agency for Science Technology and Research A STAR, 30 Biopolis Street, 07 01, Matrix 138671, Singapore
    Virol J 7:297. 2010
    ..quot; give the impression that HA-Q310 H would be highly dangerous or important, while careful consideration of all available data suggests that this is unlikely to be the case...
  7. ncbi A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus
    Sebastian Maurer-Stroh
    Bioinformatics Institute BII, ASTAR Singapore Bioinformatics Institute BII, A STAR Bioinformatics Institute BII A STAR Singapore and National Public Health Laboratory, Ministry of Health, Singapore
    PLoS Curr 2:RRN1162. 2010
    ..More clinical and experimental data are needed to determine if this mutation could alter the biology and fitness of the virus or if its increased occurrence is due to founder effects...
  8. ncbi Structural insight into the glycosylphosphatidylinositol transamidase subunits PIG-K and PIG-S from yeast
    Yew Kwang Toh
    Bioinformatics Institute, BII, Agency for Science, Technology and Research A STAR, Singapore, Singapore
    J Struct Biol 173:271-81. 2011
    ..7 nm in length and 3.4 nm in width. The two domains of yPIG-S(38-467) are tilted relative to each other. Finally, the arrangements of PIG-K and PIG-S inside the ensemble of the transamidase complex are discussed...
  9. ncbi Is LGI2 the candidate gene for partial epilepsy with pericentral spikes?
    Vachiranee Limviphuvadh
    Bioinformatics Institute BII, Agency for Science, Technology and Research A STAR, 30 Biopolis Street, Singapore 138671, Singapore
    J Bioinform Comput Biol 8:117-27. 2010
    ..Supplementary Table is available at http://www.worldscinet.com/jbcb/...
  10. ncbi Parameterization of disorder predictors for large-scale applications requiring high specificity by using an extended benchmark dataset
    Fernanda L Sirota
    Biomolecular Function Discovery Division, Bioinformatics Institute BII, Agency for Science Technology and Research A STAR, Matrix, Singapore
    BMC Genomics 11:S15. 2010
    ..For assessing their usability in automated workflows, we are interested in identifying parameter settings and threshold selections, under which the performance of these predictors becomes directly comparable...