Research Topics
Genomes and GenesSpecies | Alex T H SiaSummaryAffiliation: KK Women's and Children's Hospital Country: Singapore Publications
| Collaborators
|
Detail Information
Publications
Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative painEne Choo Tan
KK Research Centre, KK Women s and Children s Hospital, Singapore
Mol Pain 5:32. 2009....- The ongoing challenges of regional and general anaesthesia in obstetricsAlex T H Sia
Department of Anaesthesia, KK Women s and Children s Hospital, Singapore
Best Pract Res Clin Obstet Gynaecol 24:303-12. 2010..The need for involvement of a multidisciplinary team, good communication and challenges surrounding the provision of anaesthesia to such patients are discussed... - The influence of ATP-binding cassette sub-family B member -1 (ABCB1) genetic polymorphisms on acute and chronic pain after intrathecal morphine for caesarean section: a prospective cohort studyA T Sia
KK Research Centre, Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
Int J Obstet Anesth 19:254-60. 2010..We investigated the effect of ABCB1 gene polymorphisms on analgesia and the development of persistent pain in post caesarean patients... - A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesiaAlex T Sia
Department of Women s Anaesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore
Anesthesiology 109:520-6. 2008..The purpose of this study was to investigate whether this polymorphism contributes to the variability in response to morphine for postcesarean analgesia... - A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean deliverySerene Leo
Department of Women s Anaesthesia, Kandang Kerbau Women s and Children s Hospital, Singapore
Anesth Analg 109:1600-5. 2009.... - 0.2% Ropivacaine and levobupivacaine provide equally effective epidural labour analgesiaMia Supandji
Department of Anesthesia O and G, KK Women and Children Hospital, 100 Bukit Timah Road, Singapore
Can J Anaesth 51:918-22. 2004..To compare the duration of epidural analgesia induced by levobupivacaine and ropivacaine at clinically relevant doses... - Automated intermittent epidural boluses improve analgesia induced by intrathecal fentanyl during labourSebastian M H Chua
Department of Anaesthesia, Singapore General Hospital, Singapore
Can J Anaesth 51:581-5. 2004..We compared the efficacy of epidural continual intermittent boluses (CIB) with a continuous epidural infusion (CEI) in prolonging labour analgesia induced by the combined spinal epidural (CSE) technique... - Hyperbaric bupivacaine 2.5 mg prolongs analgesia compared with plain bupivacaine when added to intrathecal fentanyl 25 microg in advanced laborWendy H L Teoh
Department of Anesthesia, KK Women s and Children s Hospital, Singapore
Anesth Analg 97:873-7. 2003..05). The side-effect profile was similar. Under these circumstances, hyperbaric bupivacaine conferred an increased duration of IT analgesia compared with plain bupivacaine... - Failure of augmentation of labor epidural analgesia for intrapartum cesarean delivery: a retrospective reviewShuying Lee
Department of Women s Anesthesia, KK Women s and Children s Hospital, Singapore, Republic of Singapore
Anesth Analg 108:252-4. 2009..001), >or=2 episodes of breakthrough pain during labor (P < 0.001) and prolonged duration of neuraxial labor analgesia (P = 0.02)... - Ethnic differences in pain perception and patient-controlled analgesia usage for postoperative painEne Choo Tan
KK Research Centre, KK Women s and Children s Hospital, and the Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
J Pain 9:849-55. 2008..Inadequate management of pain after cesarian deliveries might affect the emotional well-being and physical recovery of patients and affect mother-child bonding... - Combined spinal epidural analgesia for labor with and without 3 ml of 1.5% epidural lidocaineYvonne Lim
Department of Anesthesia, KK Women s and Children s Hospital, Singapore, Singapore
Med Sci Monit 13:CR9-13. 2007..5% lidocaine injected immediately after the initiation of combined spinal epidural analgesia and followed by a continuous epidural infusion would prolong the duration of analgesia and decrease the incidence of breakthrough pain... - Comparison of intrathecal levobupivacaine with and without fentanyl in combined spinal epidural for labor analgesiaYvonne Lim
Department of Anesthesia O and G, KK Women s and Children s Hospital, Singapore, Singapore
Med Sci Monit 10:PI87-91. 2004..This may decrease the need for supplemental labor pain relief and the anesthetists' workload in the delivery suite... - Colloid preload versus coload for spinal anesthesia for cesarean delivery: the effects on maternal cardiac outputWendy H L Teoh
Department of Women s Anesthesia, KK Women s and Children s Hospital, Singapore
Anesth Analg 108:1592-8. 2009..4 [Voluven 6%]) and an identical coload on maternal CO and the incidence of hypotension after spinal anesthesia for cesarean delivery. Secondary outcomes studied were neonatal acid- base status and predelivery vasopressor requirements... - A comparison of median effective doses of intrathecal levobupivacaine and ropivacaine for labor analgesiaAlex T Sia
Department of Anesthesia, KK Women s and Children s Hospital, Singapore
Anesthesiology 102:651-6. 2005..The study was designed to determine and compare the median effective doses (MEDs) of intrathecal ropivacaine with levobupivacaine for labor analgesia... - A comparison of a basal infusion with automated mandatory boluses in parturient-controlled epidural analgesia during laborAlex T Sia
Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
Anesth Analg 104:673-8. 2007..We hypothesized that epidural local anesthetic consumption would be lower if basal intermittent boluses were used instead of a basal infusion... - Addition of bupivacaine 1.25 mg to fentanyl confers no advantage over fentanyl alone for intrathecal analgesia in early labourEvangeline H L Lim
Department of Anaesthesia, KK Women's and Children's Hospital, Singapore
Can J Anaesth 49:57-61. 2002..CONCLUSION: We found no advantage of adding 1.25 mg bupivacaine to fentanyl 25 microg. At this dose, the baricity of bupivacaine has no effect on the duration of analgesia... - A randomised trial of the analgesic efficacy of ultrasound-guided transversus abdominis plane block after caesarean delivery under general anaesthesiaTerry T Tan
Coombe Women and Infants University Hospital, Dublin, Ireland
Eur J Anaesthesiol 29:88-94. 2012..Previous studies examining the efficacy of transversus abdominis plane block after caesarean section have mostly been in parturients under spinal anaesthesia... - Combined spinal epidural does not cause a higher sensory block than single shot spinal technique for cesarean delivery in laboring womenYvonne Lim
Department of Women s Anesthesia, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore 229899
Anesth Analg 103:1540-2. 2006..We tested whether this is true also in laboring women who may have variable epidural pressures... - Combined spinal epidural causes higher level of block than equivalent single-shot spinal anesthesia in elective cesarean patientsFarida Ithnin
Department of Women's Anesthesia, KK Women's and Children's Hospital, Singapore
Anesth Analg 102:577-80. 2006.... - A comparison of duration of analgesia of intrathecal 2.5 mg of bupivacaine, ropivacaine, and levobupivacaine in combined spinal epidural analgesia for patients in laborYvonne Lim
Department of Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Republic of Singapore
Anesth Analg 98:235-9, table of contents. 2004..5 mg bupivacaine significantly prolongs the duration of analgesia in laboring patients compared with ropivacaine or levobupivacaine. This suggests that, at clinically relevant doses, bupivacaine may have greater potency...