Research Topics
| Zhaoqing ChuSummaryCountry: Singapore Publications
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Detail Information
Publications
Adaptive expression responses in the Pol-gamma null strain of S. pombe depleted of mitochondrial genomeZhaoqing Chu
Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore
BMC Genomics 8:323. 2007..Petite strains fail to grow on non-fermentable carbon sources. However, it is not clear whether the Pol-gamma is required for mtDNA maintenance in the petite-negative fission yeast Schizosaccharomyces pombe...- Deconvolution of chromatin immunoprecipitation-microarray (ChIP-chip) analysis of MBF occupancies reveals the temporal recruitment of Rep2 at the MBF target genesMajid Eshaghi
Laboratory of Systems Biology, Genome Institute of Singapore, Singapore, Republic of Singapore
Eukaryot Cell 10:130-41. 2011..We propose that the MBF activator Rep2 plays a role in mediating the cell cycle-specific transcription through the recruitment of RNAP-II to the MBF-bound G(1)/S-phase genes... - Genomic binding profiling of the fission yeast stress-activated MAPK Sty1 and the bZIP transcriptional activator Atf1 in response to H2O2Majid Eshaghi
Systems Biology, Genome Institute of Singapore, Singapore, Republic of Singapore
PLoS ONE 5:e11620. 2010..pombe. However, it is unclear whether all of the H(2)O(2)-induced genes are directly regulated by the Sty1-Atf1 pathway and involved in growth fitness under H(2)O(2)-induced stress conditions... - Global profiling of DNA replication timing and efficiency reveals that efficient replication/firing occurs late during S-phase in S. pombeMajid Eshaghi
Systems Biology, Genome Institute of Singapore, Singapore, Singapore
PLoS ONE 2:e722. 2007..Current studies of genome-wide DNA replication profiles have focused on the DNA replication timing and origin location. However, the replication and/or firing efficiency of the individual origins on the genomic scale remain unclear... - A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeastZhaoqing Chu
Systems Biology, Genome Institute of Singapore, A STAR, Biopolis, Singapore, Singapore
Mol Cell Biol 29:4959-70. 2009..We propose that oscillation of Rep2 plays a role in regulation of periodic transcription of the MBF-dependent genes during cell cycle progression... - Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeastZhaoqing Chu
Biological Investigations and Computational and Mathematical Biology, Genome Institute of Singapore, Singapore 118672
Mol Biol Cell 18:1756-67. 2007..Together, our results demonstrate that Rad3p and Cds1p modulate transcriptional response during the onset of S phase arrest... - Knockout of the AtCESA2 gene affects microtubule orientation and causes abnormal cell expansion in ArabidopsisZhaoqing Chu
Temasek Life Sciences Laboratory, National University of Singapore, Singapore 117604
Plant Physiol 143:213-24. 2007..We also demonstrated that the zinc finger-like domain of AtCESA2 could homodimerize, possibly contributing to rosette assemblies of cellulose synthase A within plasma membranes...