Paolo G V Martini

Summary

Affiliation: Shire BioChem Inc

Publications

  1. ncbi Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts
    Sarah M Peterson
    Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA
    BMC Cancer 10:427. 2010
  2. ncbi Comparative expression analysis of four breast cancer subtypes versus matched normal tissue from the same patients
    Paolo G V Martini
    Serono Research Institute, Systems Biology, 1 Technology Place, Rockland, MA, USA
    J Steroid Biochem Mol Biol 109:207-11. 2008
  3. ncbi Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases
    Paolo G V Martini
    Department of Protein Expression and Purification Research, Shire Human Genetic Therapies Inc, 700 Main Street, Cambridge, MA 02139, USA
    BMC Immunol 11:43. 2010
  4. ncbi Modulation of estrogen receptor activity by selective coregulators
    Paolo G V Martini
    Department of Molecular and Integrative Physiology, College of Medicine, University of Illinois, 524 Burrill Hall, 407 South Goodwin Avenue, Urbana, IL 61801, USA
    J Steroid Biochem Mol Biol 85:117-22. 2003
  5. ncbi Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97)
    Ramji R Rajendran
    Department of Cell and Structural Biology, University of Illinois, Urbana, Illinois 61801, USA
    J Biol Chem 278:4628-38. 2003
  6. ncbi Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species
    Raegan O'Lone
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    Mol Endocrinol 21:1281-96. 2007

Collaborators

  • Christian Lood
  • Goran Jonsson
  • Benita S Katzenellenbogen
  • Sarah M Peterson
  • Raegan O'Lone
  • Ramji R Rajendran
  • Kristen Tobin
  • Alicia Gomez-Yafal
  • Lucy Liaw
  • Alla Romashko
  • ANGELA NORTON
  • Michael F Concino
  • Andrea Iskenderian
  • Lynette Cook
  • Michael Jones
  • Michael W Heartlein
  • Michael E Mendelsohn
  • Iris Z Jaffe
  • Jadwiga Bienkowska
  • Katrin Knorr
  • Michael E Schaffer
  • Richard H Karas
  • Ulla Hansen
  • Jonna Frasor
  • Rashna D Balsara
  • Anne C Nye

Detail Information

Publications6

  1. ncbi Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts
    Sarah M Peterson
    Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA
    BMC Cancer 10:427. 2010
    ..We hypothesized that sulfatase activity in the tumor microenvironment would regulate tumor growth in vivo...
  2. ncbi Comparative expression analysis of four breast cancer subtypes versus matched normal tissue from the same patients
    Paolo G V Martini
    Serono Research Institute, Systems Biology, 1 Technology Place, Rockland, MA, USA
    J Steroid Biochem Mol Biol 109:207-11. 2008
    ....
  3. ncbi Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases
    Paolo G V Martini
    Department of Protein Expression and Purification Research, Shire Human Genetic Therapies Inc, 700 Main Street, Cambridge, MA 02139, USA
    BMC Immunol 11:43. 2010
    ..Infusions with normal fresh frozen plasma for the treatment of associated disease have demonstrated therapeutic effects but so far protein replacement therapy has not been evaluated...
  4. ncbi Modulation of estrogen receptor activity by selective coregulators
    Paolo G V Martini
    Department of Molecular and Integrative Physiology, College of Medicine, University of Illinois, 524 Burrill Hall, 407 South Goodwin Avenue, Urbana, IL 61801, USA
    J Steroid Biochem Mol Biol 85:117-22. 2003
    ..Analysis of the mechanisms underlying the activities of these two proteins highlights a new role for REA and PTalpha as activity-modulating proteins that confer receptor specificity...
  5. ncbi Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97)
    Ramji R Rajendran
    Department of Cell and Structural Biology, University of Illinois, Urbana, Illinois 61801, USA
    J Biol Chem 278:4628-38. 2003
    ..Our findings add to the growing evidence that RNA helicases can associate with nuclear receptors and function as coregulators to modulate receptor transcriptional activity...
  6. ncbi Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species
    Raegan O'Lone
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    Mol Endocrinol 21:1281-96. 2007
    ..Overall, these findings provide a foundation for understanding the molecular basis for estrogen effects on vasculature gene expression...