The use of oral glucose tolerance tests to risk stratify for new-onset diabetes after transplantation: An underdiagnosed phenomenonAdnan Sharif
Nephrology and Transplant Directorate, University Hospital of Wales, Heath Park, Cardiff, UK
Transplantation 82:1667-72. 2006
..The aim of this study was to use an oral glucose tolerance test (OGTT) to risk stratify for NODAT and IGT in renal transplant recipients and to relate cardiovascular and phenotypic risk with glycemic dysregulation...
- Cyclophosphamide exposure pretransplant is associated with complications in the first year after kidney transplant
Adnan Sharif
Department of Nephrology and Transplantation, Renal Institute of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK
Exp Clin Transplant 9:236-40. 2011
..Long-term bone marrow damage associated with cyclophosphamide could manifest with myelotoxic complications after transplant in the context of the immunosuppressant, but evidence for this has not been published...
- Should metformin be our antiglycemic agent of choice post-transplantation?
A Sharif
Renal Institute of Birmingham, Queen Elizabeth Hospital, Birmingham, UK
Am J Transplant 11:1376-81. 2011
....
- Current and emerging antiglycaemic pharmacological therapies: the renal perspective
Adnan Sharif
Renal Institute of Birmingham, Queen Elizabeth Hospital, Birmingham, UK
Nephrology (Carlton) 16:468-75. 2011
..A tailored and individualized approach to treatment of diabetes mellitus in the context of renal disease is essential to maintain optimum care and this article should act as a supplement to existing guidelines and treatment algorithms...
- Update on dialysis economics in the UK
Adnan Sharif
Renal Institute of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK
Perit Dial Int 31:S58-62. 2011
..This article explores the role of dialysis economics and implications for UK renal replacement therapy programs...
- Risk factors for new-onset diabetes after kidney transplantation
Adnan Sharif
Department of Nephrology and Transplantation, Renal Institute of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK
Nat Rev Nephrol 6:415-23. 2010
....
- Impending hyperglycemia in normoglycemic renal transplant recipients--an experimental predictive surrogate
Adnan Sharif
Department of Nephrology and Transplantation, Renal Institute of Birmingham, University Hospital Birmingham, Edgbaston, Birmingham, United Kingdom
Transplantation 89:1341-6. 2010
..The aim of this study was to derive a simple surrogate for the DI to expose predysglycemic abnormalities posttransplantation...
- Comparison of rival metabolic syndrome classifications against pathophysiological markers in renal transplant recipients
Adnan Sharif
Nephrology and Transplantation Department, University Hospital Birmingham, Edgbaston, Birmingham, United Kingdom
Transplantation 89:347-52. 2010
..We compared the two classifications against insulin resistance, subclinical inflammation, and central obesity in renal transplant recipients...
- Insulin resistance indexes in renal transplant recipients maintained on tacrolimus immunosuppression
Adnan Sharif
University Hospital Birmingham, Edgbaston, Birmingham, United Kingdom
Transplantation 89:327-33. 2010
..We aimed to assess these indexes in renal transplant recipients on tacrolimus as primary immunosuppressant...
- Metabolic syndrome and solid-organ transplantation
A Sharif
Renal Institute of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK
Am J Transplant 10:12-7. 2010
..The purpose of this review is to update transplant clinicians with our current understanding of the metabolic syndrome, review the transplantation literature and examine the controversies surrounding the concept...
- The effect of rosuvastatin on insulin sensitivity and pancreatic beta-cell function in nondiabetic renal transplant recipients
A Sharif
University Hospital Birmingham, Edgbaston, Birmingham, United Kingdom
Am J Transplant 9:1439-45. 2009
..106, p = 0.049) and insulin sensitivity (R(2)= 0.136, p = 0.029). Rosuvastatin fails to modify glucose metabolism in low-risk patients posttransplantation but HbA1c is a useful surrogate for declining glycemic control...
- Influence of lifestyle modification in renal transplant recipients with postprandial hyperglycemia
Adnan Sharif
Nephrology and Transplant Directorate, University Hospital Wales, Cardiff, CF, United Kingdom
Transplantation 85:353-8. 2008
..This study aimed to assess the benefit of intensive lifestyle modification in this high-risk group and to contrast this with the natural evolution of glucose metabolism after transplantation...
- Complications associated with new-onset diabetes after kidney transplantation
Adnan Sharif
Department of Nephrology and Transplantation, Renal Institute of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK
Nat Rev Nephrol 8:34-42. 2012
....
- Meta-analysis of calcineurin-inhibitor-sparing regimens in kidney transplantation
Adnan Sharif
Renal Institute of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom
J Am Soc Nephrol 22:2107-18. 2011
..In conclusion, this meta-analysis suggests that reducing exposure to calcineurin inhibitors immediately after kidney transplantation may improve clinical outcomes...
- Assessing and comparing rival definitions of delayed renal allograft function for predicting subsequent graft failure
Jason Moore
Department of Nephrology and Transplantation, Renal Institute of Birmingham, University Hospital Birmingham, Birmingham, United Kingdom
Transplantation 90:1113-6. 2010
..However, an association between fDGF and long-term graft failure has not been fully established, and it is unknown whether fDGF is a better marker of subsequent outcomes than dDGF...
