Research Topics
| R JambouSummaryAffiliation: Institut Pasteur Country: Senegal Publications
| Collaborators
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Detail Information
Publications
Invasion of Africa by a single pfcrt allele of South East Asian typeFrederic Ariey
Institut Pasteur du Cambodge, Phnom Penh, Cambodia
Malar J 5:34. 2006..Many questions remain about the actual selection and spreading process of CQR parasites, and about the evolution of the ancestral mutant gene(s) during spreading...
World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibilityDavid J Bacon
Parasitology Program, Naval Medical Research Center Detachment, Lima, Peru
Malar J 6:120. 2007..Such a network would facilitate the rapid detection of strains with novel antimalarial resistance profiles and investigate suitable alternative treatments with retained efficacy...
Malaria in the highlands of Madagascar after five years of indoor house spraying of DDTR Jambou
Pasteur Institute of Madagascar, Madagascar
Trans R Soc Trop Med Hyg 95:14-8. 2001..Our study suggests that this strategy should be reinforced by the spraying of DDT in the marginal zones in order to consolidate the results obtained at higher altitudes...
Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6Ronan Jambou
Unite d immunologie, Institut Pasteur de Dakar, BP 220, Dakar, Senegal
Lancet 366:1960-3. 2005..0001, Mann-Whitney). All resistant isolates came from areas with uncontrolled use of artemisinin derivatives. This rise in resistance indicates the need for increased vigilance and a coordinated and rapid deployment of drug combinations...
South-East Asian ovalocytosis among the population of the Highlands of Madagascar: a vestigé of the island's settlementT Rabe
Pasteur Institute of Madagascar, P.O. Box 1274, Antananarivo Zip 101, Madagascar
Trans R Soc Trop Med Hyg 96:143-4. 2002..Most harboured the deletion in the band 3 gene characteristic of South-East Asian ovalocytosis. This genetic trait supports the Indonesian origin of the Madagascar settlement...
Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversityRonan Jambou
Institut Pasteur de Dakar, BP 220, Dakar, Senegal
PLoS ONE 5:e9424. 2010..One possible contributor could be the frequency of haemoglobinopathies that are associated with calcium dysregulation in the erythrocyte...
Differential antibody responses to Plasmodium falciparum glycosylphosphatidylinositol anchors in patients with cerebral and mild malariaRonald Perraut
Unite d immunologie, Institut Pasteur de Dakar, 36 Av Pasteur, BP 220, Dakar, Senegal
Microbes Infect 7:682-7. 2005..These results are consistent with a potential anti-toxin role for anti-GPI antibodies associated with protection against cerebral malaria...
Malaria transmission in Southern Madagascar: influence of the environment and hydro-agricultural works in sub-arid and humid regions. Part 1. Entomological investigationsL Marrama
Unité d Epidémiologie de l Institut Pasteur de Dakar, 36 Avenue Pasteur, BP 220, Dakar, Senegal
Acta Trop 89:193-203. 2004..mascarensis, despite the presence of A. gambiae s.s. and A. funestus. These results are discussed with reference to the impact of irrigation on malaria in Africa ("the paddies paradox")...
Accumulation of CVIET Pfcrt allele of Plasmodium falciparum in placenta of pregnant women living in an urban area of Dakar, SenegalMakhtar Niang
Unite d immunologie, Institut Pasteur de Dakar, Senegal
J Antimicrob Chemother 62:921-8. 2008..The objective of this study was to analyse the selection of drug-resistant parasites in the placenta in an area where chloroquine was still recommended as prophylaxis...
Chronic infection during placental malaria is associated with up-regulation of cycloxygenase-2Demba Sarr
Institut Pasteur de Dakar, Dakar, Senegal
Malar J 9:45. 2010..The role of COX during PM was questioned by quantifying at delivery COX-1, COX-2, 15-LOX, and IL-10 expression in two groups of malaria infected and uninfected placenta...
Performance evaluation of automated depolarization analysis for detecting clinically unsuspected malaria in endemic countriesJacques-Albert Dromigny
Laboratoire de Biologie, Institut Pasteur de Dakar, 36 Avenue Pasteur, B.P. 220, Dakar, Senegal
Trans R Soc Trop Med Hyg 99:430-9. 2005..2%) of these had atypical PCM. The detection of clinically unrecognized malaria infection as part of a routine FBC procedure is a potentially useful extended application for laboratories in countries with endemic malaria...
Countrywide survey shows very high prevalence of Plasmodium falciparum multilocus resistance genotypes in CambodiaNimol Khim
Faculte de Pharmacie, UFR Sciences Pharmaceutiques, UMR INRA Université d Immunologie Parasitaire et de Vaccinologie, 31, avenue Monge Parc Grandmont, 37200 Tours, France
Antimicrob Agents Chemother 49:3147-52. 2005..Our findings show an alarming rate of multilocus resistance genotypes in Cambodia, requiring diligent surveillance and imposing limitations on possible future drug combinations...
Current absence of pyrimethamine resistance of Plasmodium falciparum in MadagascarMilijaona Randrianarivelojosia
Groupe de Recherche sur le Paludisme, Institut Pasteur de Madagascar, B P 1274, Antananarivo 101, Madagascar
Trans R Soc Trop Med Hyg 96:557-9. 2002..The results indicate the absence of the dhfr encoding Asn108 and Thr108 among tested clinical isolates. The sensitivity of P. falciparum to pyrimethamine-based antimalarial drugs in Madagascar is discussed...
Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sitesMarie Therese Ekala
Immunologie Moléculaire des Parasites, CNRS URA 2581, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, Paris, France
Malar J 6:164. 2007..To this end, a large molecular survey was conducted in several malaria endemic areas where atovaquone was not yet in regular use...
