Detail Information
Publications
Challenges in the development of hydrate phases as active pharmaceutical ingredients--an exampleMartin P Feth
Sanofi Aventis Deutschland GmbH, Chemical Development, Industriepark Hochst, Frankfurt am Main, Germany
Eur J Pharm Sci 42:116-29. 2011..g. particle size d 90 value<20 ?m, water content and crystallographic phase corresponding to desired form 1 of SAR474832)...
New technology for the investigation of water vapor sorption-induced crystallographic form transformations of chemical compounds: a water vapor sorption gravimetry-dispersive Raman spectroscopy couplingMartin Philipp Feth
Sanofi Aventis Deutschland GmbH, Research and Development, LGCR, Chemical Development, Process and Particle Development Group, 65926 Frankfurt, Germany
J Pharm Sci 100:1080-92. 2011..This is especially interesting for physically and chemically labile hydrate phases...
