Natalia V Kovaleva

Summary

Country: Russia

Publications

  1. ncbi Parental mosaicism for trisomy 21: problems with its detection and an approach to determining its population rate
    Natalia V Kovaleva
    St. Petersburg Medical Academy of Postgraduate Studies under the Federal Agency of Health Care and Social Development, St. Petersburg, Russian Federation
    Genet Test 11:341-4. 2007
  2. ncbi Under-ascertainment of mosaic carriers of balanced homologous acrocentric translocations and isochromosomes
    Natalia V Kovaleva
    Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 121:180-7. 2003
  3. ncbi Epidemiology of double aneuploidies involving chromosome 21 and the sex chromosomes
    Natalia V Kovaleva
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 134:24-32. 2005
  4. ncbi Sex-specific chromosome instability in early human development
    Natalia V Kovaleva
    St Petersburg Centre for Medical Genetics, St Petersburg, Russian Federation
    Am J Med Genet A 136:401-13. 2005
  5. ncbi Nonmosaic balanced homologous translocations of major clinical significance: some may be mosaic
    Natalia V Kovaleva
    St Petersburg Center for Medical Genetics, St Petersburg, Russian Federation
    Am J Med Genet A 143:2843-50. 2007
  6. ncbi Germ-line transmission of trisomy 21: Data from 80 families suggest an implication of grandmaternal age and a high frequency of female-specific trisomy rescue
    Natalia V Kovaleva
    Scientific Research Centre at Saint Petersburg State Pediatric Medical Academy under the Federal Agency of Health Care and Social Development, St Petersburg, Russian Federation
    Mol Cytogenet 3:7. 2010

Collaborators

Detail Information

Publications6

  1. ncbi Parental mosaicism for trisomy 21: problems with its detection and an approach to determining its population rate
    Natalia V Kovaleva
    St. Petersburg Medical Academy of Postgraduate Studies under the Federal Agency of Health Care and Social Development, St. Petersburg, Russian Federation
    Genet Test 11:341-4. 2007
  2. ncbi Under-ascertainment of mosaic carriers of balanced homologous acrocentric translocations and isochromosomes
    Natalia V Kovaleva
    Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 121:180-7. 2003
    ..However, given that mosaicism may be restricted to the gonads, prenatal testing is likely to be desired by the family whether or not mosaicism is found...
  3. ncbi Epidemiology of double aneuploidies involving chromosome 21 and the sex chromosomes
    Natalia V Kovaleva
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 134:24-32. 2005
    ..9 in 48,XXY,+21 cases and a mean age of 27.9 in 48,XYY,+21 cases (P < 0.01). Maternal age-related factors, rather than genetic predisposition, may play a more important role in the etiology of the most common DA, 48,XXY,+21...
  4. ncbi Sex-specific chromosome instability in early human development
    Natalia V Kovaleva
    St Petersburg Centre for Medical Genetics, St Petersburg, Russian Federation
    Am J Med Genet A 136:401-13. 2005
    ..The data obtained suggest that females may have gonadal mosaicism for aneuploidies and structural rearrangements more often than males. This may lead to the maternal origin bias in offspring with trisomies or structural rearrangements...
  5. ncbi Nonmosaic balanced homologous translocations of major clinical significance: some may be mosaic
    Natalia V Kovaleva
    St Petersburg Center for Medical Genetics, St Petersburg, Russian Federation
    Am J Med Genet A 143:2843-50. 2007
    ..However, additional studies of healthy carriers of homologous REA of chromosome 14 or 15 should not be done. (c) 2007 Wiley-Liss, Inc...
  6. ncbi Germ-line transmission of trisomy 21: Data from 80 families suggest an implication of grandmaternal age and a high frequency of female-specific trisomy rescue
    Natalia V Kovaleva
    Scientific Research Centre at Saint Petersburg State Pediatric Medical Academy under the Federal Agency of Health Care and Social Development, St Petersburg, Russian Federation
    Mol Cytogenet 3:7. 2010
    ..Studies in families of gonadal mosaicism (GM) carriers might help resolving some of these problems...