Research Topics
Species | Victor P ShcherbakovSummaryAffiliation: Institute of Problems of Chemical Physics Country: Russia Publications
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Detail Information
Publications
Biological species is the only possible form of existence for higher organisms: the evolutionary meaning of sexual reproductionVictor P Shcherbakov
Institute of Problems of Chemical Physics RAS, Chernogolovka, Moscow Region, Russia
Biol Direct 5:14. 2010..Instead, after mating with "ordinary" individuals, these genotypes scatter and rearrange in new gene combinations, thus preventing the winner from exploiting the success...
Focused genetic recombination of bacteriophage t4 initiated by double-strand breaksVictor Shcherbakov
Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region, 142432 Russia
Genetics 162:543-56. 2002..The advantages of this localized or focused recombination over that distributed along the chromosome, as a model for studying the recombination-replication pathway in T4 in vivo, are discussed...
Double-strand break repair in bacteriophage T4: coordination of DNA ends and effects of mutations in recombinational genesVictor P Shcherbakov
Institute of Problems of Chemical Physics RAS, Chernogolovka, Moscow Region 142432, Russia
DNA Repair (Amst) 5:773-87. 2006..Phage topoisomerase II (gp39-52-60) is indispensable for growth in the DNA arrest mutants: the doubles 47(-)39(-), uvsX 39(-) and 59(-)39(-) are lethal...
Double-strand break repair in bacteriophage T4: recombination effects of 3'-5' exonuclease mutationsVictor P Shcherbakov
Institute of Problems of Chemical Physics RAS, Chernogolovka, Moscow Region 142432, Russia
Genetics 174:1729-36. 2006..The role of the proofreading exonuclease in the formation of a robust replicative fork is discussed...
Genetic recombination induced by DNA double-strand break in bacteriophage T4: nature of the left/right biasVictor P Shcherbakov
Institute of Problems of Chemical Physics, RAS, Chernogolovka, Moscow Region 142432, Russia
DNA Repair (Amst) 7:890-901. 2008..The idea is substantiated that the double-stranded to single-stranded DNA transition edge (not ss-DNA tip) serves as an actual recombinogenic element...
On the mutagenicity of homologous recombination and double-strand break repair in bacteriophageVictor P Shcherbakov
Institute of Problems of Chemical Physics RAS, Chernogolovka, Moscow Region, Russia
DNA Repair (Amst) 10:16-23. 2011..e., preferential replication of the sequences already involved in replication. We discuss the DSB repair pathway in the absence of UvsX recombinase...
Endonuclease VII is a key component of the mismatch repair mechanism in bacteriophage T4Victor P Shcherbakov
Institute of Problems of Chemical Physics RAS, Chernogolovka, Moscow Region 142432, Russia
DNA Repair (Amst) 10:356-62. 2011..This role for endo VII was suggested previously from biochemical studies, but this is its first in vivo demonstration...
