Anti-atherogenic effects of the acyl-CoA:cholesterol acyltransferase inhibitor, avasimibe (CI-1011), in cultured primary human macrophagesAnnabelle Rodriguez
Departments of Medicine, Sinai Hospital of Baltimore, The Johns Hopkins University School of Medicine, Schapiro Research Building, Room 200, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA
Atherosclerosis 161:45-54. 2002
..Thus, CI-1011 exerted anti-atherogenic effects by reducing TC accumulation, inhibiting acLDL binding, and by limiting lipid storage in HMMs...
- Clinical impact of scavenger receptor class B type I gene polymorphisms on human female fertility
Melissa Yates
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Hum Reprod 26:1910-6. 2011
..The goal of this study was to evaluate the association of SCARB1 single nucleotide polymorphisms (SNPs) and fertility outcomes in women undergoing IVF...
- Deficiency of scavenger receptor class B type I negatively affects progesterone secretion in human granulosa cells
Antonina Kolmakova
Department of Medicine, Division of Endocrinology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21215, USA
Endocrinology 151:5519-27. 2010
..In conclusion, SR-BI protein deficiency, in part, might explain progesterone deficiency in some infertile women...
- Chronic intermittent hypoxia induces atherosclerosis
Vladimir Savransky
Division of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Am J Respir Crit Care Med 175:1290-7. 2007
..A causal link between obstructive sleep apnea and atherosclerosis has not been established...
- A synonymous variant in scavenger receptor, class B, type I gene is associated with lower SR-BI protein expression and function
Jason Constantineau
Department of Medicine, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, United States
Atherosclerosis 210:177-82. 2010
..The objective was to determine if rs5888 decreased SR-BI protein expression and function in vitro...
- The impact of luteal phase support on gene expression of extracellular matrix protein and adhesion molecules in the human endometrium during the window of implantation following controlled ovarian stimulation with a GnRH antagonist protocol
Yulian Zhao
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Fertil Steril 94:2264-71. 2010
..To evaluate the impact of two different luteal phase support protocols on gene expression of extracellular matrix (ECM) proteins and adhesion molecules in the human endometrium...
- Association of scavenger receptor class B type I polymorphisms with subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis
Adam C Naj
Department of Medicine, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD, USA
Circ Cardiovasc Genet 3:47-52. 2010
..We examined this relationship in the Multi-Ethnic Study of Atherosclerosis...
- Expression of scavenger receptor-BI and low-density lipoprotein receptor and differential use of lipoproteins to support early steroidogenesis in luteinizing macaque granulosa cells
Mary Cherian-Shaw
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Endocrinology 150:957-65. 2009
....
- ACAT1 deletion in murine macrophages associated with cytotoxicity and decreased expression of collagen type 3A1
Annabelle Rodriguez
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
Biochem Biophys Res Commun 331:61-8. 2005
..02). Thus, ACAT1 KO macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1...
- Scavenger receptor class B type I protein as an independent predictor of high-density lipoprotein cholesterol levels in subjects with hyperalphalipoproteinemia
Michael West
Department of Medicine, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
J Clin Endocrinol Metab 94:1451-7. 2009
..In mice, scavenger receptor class B, type I (SR-BI) receptor protein deficiency is associated with elevated high-density lipoprotein (HDL)-cholesterol (HDL-C) levels...
- Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation
Christopher W Lipari
Department of Gynecology and Obstetrics, Division of Reproductive Endocrinology and Infertility, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Fertil Steril 91:1316-8. 2009
....
- Intermittent hypoxia induces hyperlipidemia in lean mice
Jianguo Li
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
Circ Res 97:698-706. 2005
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- Association of cholesterol subfractions and carotid lipid core measured by MRI
Milind Y Desai
Arterioscler Thromb Vasc Biol 25:e110-1. 2005
