Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia?Michael P Murphy
Division of Vascular Surgery, Indiana University School of Medicine, Indiana, USA
J Transl Med 6:45. 2008
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- Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions
Wan Zhang Yang
Nanshan Affiliated Hospital of Guangdong Medical College, Shenzhen, China
J Transl Med 8:75. 2010
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- Stem cell therapy for autism
Thomas E Ichim
Medistem Laboratories Inc, Tempe, Arizona, USA
J Transl Med 5:30. 2007
..Additionally, anecdotal clinical cases have reported responses in autistic children receiving cord blood CD34+ cells. We propose the combined use of MSC and cord blood CD34+cells may be useful in the treatment of autism...
- Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis
Neil H Riordan
Medistem Inc, San Diego, CA, USA
J Transl Med 7:29. 2009
..Based on this rationale and initial experiences, we propose controlled trials of autologous SVF in various inflammatory conditions...
- Autologous stromal vascular fraction cells: a tool for facilitating tolerance in rheumatic disease
Thomas E Ichim
Medistem Inc, San Diego, CA, USA
Cell Immunol 264:7-17. 2010
..We discuss the application of this autologous cell source in the context of rheumatoid arthritis, concluding with some practical examples of its applications...
- Tumor vaccines in 2010: need for integration
David Koos
Entest BioMedical, San Diego, CA, USA
Cell Immunol 263:138-47. 2010
..In this review we describe major advances in our understanding of tumor escape from immunological pressure and provide some possible therapeutic scenarios for enhancement of efficacy in future cancer vaccine trials...
- Combination stem cell therapy for heart failure
Thomas E Ichim
Medistem Inc, San Diego, USA
Int Arch Med 3:5. 2010
..We conclude by describing a case report of a heart failure patient treated with a combination stem cell protocol in an attempt to augment beneficial aspects of cord blood CD34 cells and mesenchymal-like stem cells...
- Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report
Thomas E Ichim
Medistem Inc, San Diego, USA
Int Arch Med 3:30. 2010
..Recovery of muscle, bowel and sexual function was noted, along with a decrease in ASIA score to "D". This case supports further investigation into allogeneic-based stem cell therapies for SCI...
- Mesenchymal stem cells as anti-inflammatories: implications for treatment of Duchenne muscular dystrophy
Thomas E Ichim
Medistem Inc, San Diego, CA 92122, USA
Cell Immunol 260:75-82. 2010
..We conclude by describing one practical scenario of stem cell therapy for DMD...
- Feasibility investigation of allogeneic endometrial regenerative cells
Zhaohui Zhong
Medistem Inc, San Diego, USA
J Transl Med 7:15. 2009
..These preliminary data suggest feasibility of clinical ERC administration and support further studies with this novel stem cell type...
- Immunotherapy for melanoma: current status and perspectives
Doru T Alexandrescu
Division of Dermatology, University of California at San Diego, San Diego, CA, USA
J Immunother 33:570-90. 2010
..The need to engineer better immune interactions and to boost positive feedback loops appear crucial for the future of melanoma therapy, which ultimately resides in our understanding of the complexity of immune responses in this disease...
- Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
Nina A Mikirova
Medistem Inc, San Diego, California, USA
J Transl Med 8:34. 2010
..These data suggest Stem-Kine supplementation may be useful as a stimulator of reparative processes associated with mobilization of hematopoietic and endothelial progenitors...
