Ravi Rajagopalan

Summary

Publications

  1. ncbi Inhibition and binding kinetics of the hepatitis C virus NS3 protease inhibitor ITMN-191 reveals tight binding and slow dissociative behavior
    Ravi Rajagopalan
    InterMune Inc, 3280 Bayshore Boulevard, Brisbane, California 94005, USA
    Biochemistry 48:2559-68. 2009
  2. ncbi Optimization of the multiple enzymatic activities of the hepatitis C virus NS3 protein
    Shawn Misialek
    InterMune, Brisbane, CA 94005, USA
    Anal Biochem 394:138-40. 2009

Collaborators

Detail Information

Publications2

  1. ncbi Inhibition and binding kinetics of the hepatitis C virus NS3 protease inhibitor ITMN-191 reveals tight binding and slow dissociative behavior
    Ravi Rajagopalan
    InterMune Inc, 3280 Bayshore Boulevard, Brisbane, California 94005, USA
    Biochemistry 48:2559-68. 2009
    ..Slow dissociation is not observed with closely related macrocyclic inhibitors of NS3, suggesting that members of this class may display distinct binding kinetics...
  2. ncbi Optimization of the multiple enzymatic activities of the hepatitis C virus NS3 protein
    Shawn Misialek
    InterMune, Brisbane, CA 94005, USA
    Anal Biochem 394:138-40. 2009
    ..These conditions enable a particularly sensitive protease assay that uses picomolar concentrations of NS3...