Fatima Martel

Summary

Affiliation: University of Porto
Country: Portugal

Publications

  1. ncbi A simple method for elimination of false positive results in RT-PCR
    Fatima Martel
    Department of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany
    J Biochem Mol Biol 35:248-50. 2002
  2. ncbi Recent advances on the importance of the serotonin transporter SERT in the rat intestine
    F Martel
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Pharmacol Res 54:73-6. 2006
  3. ncbi In vitro and in vivo effect of fluoxetine on the permeability of 3H-serotonin across rat intestine
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine, University of Porto, Portugal
    Can J Physiol Pharmacol 82:940-50. 2004
  4. ncbi An update on the extraneuronal monoamine transporter (EMT): characteristics, distribution and regulation
    F Martel
    Institute of Pharmacology and Therapeutics, Faculty of Medicine, 4200 319 Porto, Portugal
    Curr Drug Metab 4:313-8. 2003
  5. ncbi The effect of high glucose on SERT, the human plasmalemmal serotonin transporter
    Pedro Goncalves
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Nutr Neurosci 11:244-50. 2008
  6. ncbi Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT)
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    J Pharmacol Exp Ther 306:355-62. 2003
  7. ncbi Absorption of folate by Caco-2 cells is not affected by high glucose concentration
    Fatima Martel
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    Eur J Pharmacol 551:19-26. 2006
  8. ncbi Uptake of (3)H-1-methyl-4-phenylpyridinium ((3)H-MPP(+)) by human intestinal Caco-2 cells is regulated by phosphorylation/dephosphorylation mechanisms
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine, 4200 319 Porto, Portugal
    Biochem Pharmacol 63:1565-73. 2002
  9. ncbi Effect of polyphenols on the intestinal and placental transport of some bioactive compounds
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine U 38, FCT, 4200 319 Porto, Portugal
    Nutr Res Rev 23:47-64. 2010
  10. ncbi Regulation of human extraneuronal monoamine transporter (hEMT) expressed in HEK293 cells by intracellular second messenger systems
    F Martel
    Department of Biochemistry, Faculty of Medicine, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 364:487-95. 2001

Collaborators

Detail Information

Publications54

  1. ncbi A simple method for elimination of false positive results in RT-PCR
    Fatima Martel
    Department of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany
    J Biochem Mol Biol 35:248-50. 2002
    ..Moreover, we describe here a simple and rapid method to overcome the false positive results that originate by this activity of Taq polymerase...
  2. ncbi Recent advances on the importance of the serotonin transporter SERT in the rat intestine
    F Martel
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Pharmacol Res 54:73-6. 2006
    ..Consequently, SERT inhibition will be able to cause an increase in the physiological responses of the tissue to this amine. The repercussions of this phenomenon are discussed...
  3. ncbi In vitro and in vivo effect of fluoxetine on the permeability of 3H-serotonin across rat intestine
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine, University of Porto, Portugal
    Can J Physiol Pharmacol 82:940-50. 2004
    ..In conclusion, the increase in the Papp of 3H-5-HT after chronic administration of fluoxetine suggests that this treatment is able to increase the extracellular concentration of 3H-5-HT at the intestinal level...
  4. ncbi An update on the extraneuronal monoamine transporter (EMT): characteristics, distribution and regulation
    F Martel
    Institute of Pharmacology and Therapeutics, Faculty of Medicine, 4200 319 Porto, Portugal
    Curr Drug Metab 4:313-8. 2003
    ....
  5. ncbi The effect of high glucose on SERT, the human plasmalemmal serotonin transporter
    Pedro Goncalves
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Nutr Neurosci 11:244-50. 2008
    ....
  6. ncbi Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT)
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    J Pharmacol Exp Ther 306:355-62. 2003
    ..In conclusion, these results suggest that human intestinal epithelial Caco-2 cells functionally express SERT, both at their apical and basolateral cell membranes...
  7. ncbi Absorption of folate by Caco-2 cells is not affected by high glucose concentration
    Fatima Martel
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    Eur J Pharmacol 551:19-26. 2006
    ....
  8. ncbi Uptake of (3)H-1-methyl-4-phenylpyridinium ((3)H-MPP(+)) by human intestinal Caco-2 cells is regulated by phosphorylation/dephosphorylation mechanisms
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine, 4200 319 Porto, Portugal
    Biochem Pharmacol 63:1565-73. 2002
    ..Moreover, uptake of (3)H-MPP(+) by Caco-2 cells and by the extraneuronal monoamine transporter (EMT) are regulated in a very similar manner, suggesting an important participation of EMT in the intestinal uptake of this compound...
  9. ncbi Effect of polyphenols on the intestinal and placental transport of some bioactive compounds
    Fatima Martel
    Department of Biochemistry, Faculty of Medicine U 38, FCT, 4200 319 Porto, Portugal
    Nutr Res Rev 23:47-64. 2010
    ....
  10. ncbi Regulation of human extraneuronal monoamine transporter (hEMT) expressed in HEK293 cells by intracellular second messenger systems
    F Martel
    Department of Biochemistry, Faculty of Medicine, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 364:487-95. 2001
    ..showed an increase in the presence of exogenous alkaline phosphatase. In conclusion, these results suggest that hEMT is regulated by phosphorylation/dephosphorylation mechanisms, being active in the dephosphorylated state...
  11. ncbi Effect of P-glycoprotein modulators on the human extraneuronal monoamine transporter
    F Martel
    Department of Biochemistry, Faculty of Medicine, 4200 319 Porto, Portugal
    Eur J Pharmacol 422:31-7. 2001
    ..As a consequence, the interaction of P-glycoprotein modulators with EMT must be taken into account, and the consequences of this interaction must not be forgotten when using such drugs in vivo...
  12. ncbi Folic acid uptake by the human syncytiotrophoblast: interference by pharmacotherapy, drugs of abuse and pathological conditions
    Elisa Keating
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Al Prof Hernani Monteiro, 4200 319 Porto, Portugal
    Reprod Toxicol 28:511-20. 2009
    ..Our results suggest that inhibition of FA placental uptake may constitute one of the mechanisms involved in the fetotoxicity of many of the compounds tested...
  13. ncbi Effect of cannabinoids upon the uptake of folic acid by BeWo cells
    Joao R Araujo
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Pharmacology 83:170-6. 2009
    ..The acute effects of cannabinoid receptor agonists do not seem to be mediated by the cannabinoid receptor, and with a few exceptions the chronic effects do not seem to be related to changes in the expression levels of FA transporters...
  14. ncbi Comparison of the transport characteristics of bioactive substances in IUGR and normal placentas
    Elisa Keating
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Pediatr Res 66:495-500. 2009
    ..These results point to an effect of "compensation for the weakness" of the IUGR placenta and pose the placenta as an active mediator of the communication between maternal and fetal environments...
  15. ncbi Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines
    Joao R Araujo
    Department of Biochemistry U38 FCT, Faculty of Medicine of Porto, University of Porto, 4200 319 Porto, Portugal
    Nutr Res 31:77-87. 2011
    ..Thus, caution is mandatory when attempting to extrapolate the observations obtained in CRC cell line studies to humans...
  16. ncbi Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters
    F Martel
    Department of Biochemistry, Faculty of Medicine, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 363:40-9. 2001
    ..In conclusion, our results suggest that uptake of organic cations at the brush-border membrane of Caco-2 cells may occur through two distinct Na+-independent transporters belonging to the ASF family: hEMT and hOCT1...
  17. ncbi Modulation of butyrate transport in Caco-2 cells
    Pedro Goncalves
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 379:325-36. 2009
    ....
  18. ncbi The effect of folate status on the uptake of physiologically relevant compounds by Caco-2 cells
    Sandra Tavares
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Eur J Pharmacol 640:29-37. 2010
    ..Moreover, these changes are associated with alterations in the mRNA levels of specific transporters for these compounds...
  19. ncbi Characterization of butyrate uptake by nontransformed intestinal epithelial cell lines
    Pedro Goncalves
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    J Membr Biol 240:35-46. 2011
    ..In conclusion, uptake characteristics of ¹?C-BT differ between IEC-6 and FHC cells. IEC-6 cells demonstrate MCT1- and SMCT1-mediated transport, while FHC cells do not...
  20. ncbi Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse
    Joao R Araujo
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Al Prof Hernani Monteiro, 4200 319 Porto, Portugal
    J Biochem 144:177-86. 2008
    ..25-1 microM) and Delta9-tetrahydrocannabinol (1 nM) decreased it. In conclusion, 3H-DG apical uptake by BeWo cells is differentially modulated by different compounds present in drinks and by drugs of abuse...
  21. ncbi Progesterone inhibits folic acid transport in human trophoblasts
    Elisa Keating
    Department of Biochemistry U38 FCT, Faculty of Medicine of Porto, University of Porto, Porto 4200 319, Portugal
    J Membr Biol 216:143-52. 2007
    ..These results suggest that progesterone inhibits RFC. In conclusion, our results show that progesterone, a sterol produced by the placenta, inhibits both FA uptake and efflux in BeWo cells and primary cultured human trophoblasts...
  22. ncbi Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo
    Elisa Keating
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    J Nutr Biochem 19:91-100. 2008
    ..01%). This reduction seems to be, at least in part, due to a reduction in FRalpha expression. These results are compatible with an association between a deficient FA supply to the placenta/fetus and ethanol toxicity in pregnancy...
  23. ncbi Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds
    Clara Lemos
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    Eur J Nutr 46:329-36. 2007
    ..In conclusion, dietary constituents may impact on intestinal folate uptake, as here shown for phenolic compounds...
  24. ncbi Intestinal permeability to glucose after experimental traumatic brain injury: effect of gadopentetate dimeglumine administration
    Alejandro Santos
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Basic Clin Pharmacol Toxicol 103:247-54. 2008
    ..Moreover, gadopentetate dimeglumine prevented these changes associated with TBI...
  25. ncbi Characterization of the transport of the organic cation [3H]MPP+ in human intestinal epithelial (Caco-2) cells
    F Martel
    Department of Biochemistry, Faculty of Medicine, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 361:505-13. 2000
    ..Absorption of [3H]MPP+ at the apical membrane seems to occur through a carrier-mediated mechanism belonging to the Amphiphilic Solute Facilitator (ASF) family of transporters, but distinct from the known members of this family...
  26. ncbi In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds
    Pedro Goncalves
    Department of Biochemistry, Faculty of Medicine, University of Porto, Porto, Portugal
    Nutr Cancer 63:282-94. 2011
    ..In conclusion, changes in uptake of BT induced by polyphenols do not correlate with changes on the effect of BT upon cell viability, cell proliferation, differentiation, and apoptosis...
  27. ncbi Lack of a significant effect of cannabinoids upon the uptake of 2-deoxy-D-glucose by Caco-2 cells
    Pedro Goncalves
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Pharmacology 82:30-7. 2008
    ..From these results, we may hypothesize that cannabinoids do not interfere with the intestinal GLUT2-mediated apical uptake of glucose...
  28. ncbi Effect of thiamine on 3H-MPP+ uptake by Caco-2 cells
    Conceição Calhau
    Department of Biochemistry, University of Porto, 4200 319, Porto, Portugal
    Pharmacol Res 48:579-84. 2003
    ..Another important conclusion is that the intestinal absorption of T+ may occur through hEMT, in Caco-2 cells...
  29. ncbi Transport of [3H]MPP+ in an immortalized rat brain microvessel endothelial cell line (RBE 4)
    F Martel
    Department of Biochemistry, Faculty of Medicine, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 363:1-10. 2001
    ..Absorption of [3H]MPP+ seems to occur through a carrier-mediated mechanism belonging to the amphiphilic solute facilitator (ASF) family of transporters, but distinct from the known members of this family...
  30. ncbi Characterization of uptake of folates by rat and human blood-brain barrier endothelial cells
    Joao R Araujo
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
    Biofactors 36:201-9. 2010
    ..In conclusion, both human and rat BBB endothelial cells show little capacity for (3)H-FA and (14)C-MTHF apical uptake. Hence, these cell lines do not appear to be a good model to study the transport of folates at the BBB...
  31. ncbi Absorption of anthocyanins through intestinal epithelial cells - Putative involvement of GLUT2
    Ana Faria
    Department of Chemistry, Chemistry Investigation Centre, University of Porto, Portugal
    Mol Nutr Food Res 53:1430-7. 2009
    ..However, the malvidin aglycone was tested and had no effect. In conclusion, anthocyanins could be absorbed through Caco-2 cells, and can interfere with their own transport and also with glucose intestinal uptake...
  32. ncbi Short-term exposure to somatostatin or muscarinic agonists reduce acetylcholine-induced 3H-MPP+ release from bovine adrenal medullary cells
    Laura Ribeiro
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319, Porto, Portugal
    J Biomed Sci 14:347-55. 2007
    ....
  33. ncbi Impact of culture media glucose levels on the intestinal uptake of organic cations
    Ana Faria
    Department of Biochemistry, Faculty of Medicine, University of Porto, Alameda Prof Hernani Monteiro, 4200 319, Porto, Portugal
    Cytotechnology 62:23-9. 2010
    ..Hence, results obtained in these conditions must be analysed with great care, since extracellular glucose levels may originate changes in organic cation nutrient and drug bioavailability...
  34. ncbi The effect of a series of organic cations upon the plasmalemmal serotonin transporter, SERT
    E Keating
    Department of Biochemistry (U38-FCT, Faculty of Medicine, 4200-319 Porto, Portugal
    Life Sci 76:103-19. 2004
    ..Knowledge on which organic cations interfere with SERT-mediated transport of 5HT will have major implications in tissues where 5HT plays important physiological roles (eg. central nervous system, intestine and placenta)...
  35. ncbi The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein
    Pedro Goncalves
    Department of Biochemistry, Faculty of Medicine, University of Porto, Porto, Portugal
    Am J Physiol Cell Physiol 301:C984-94. 2011
    ..So, interaction of BT with BCRP and with other BCRP substrates/inhibitors is clearly of major importance...
  36. ncbi Effect of some natural mineral waters in nutrient uptake by Caco-2 cells
    Pedro Goncalves
    Department of Biochemistry, Faculty of Medicine, University of Porto, Porto, Portugal
    Int J Vitam Nutr Res 80:131-43. 2010
    ..Finally, uptake of (3)H-OMG decreased after a 20-minute exposure to MgSO(4) or NaF. In conclusion, uptake of (14)C-BT and (3)H-OMG by Caco-2 cells is differently modulated by distinct mineral waters...
  37. ncbi Primary structure and functional expression of the apical organic cation transporter from kidney epithelial LLC-PK1 cells
    D Gründemann
    Department of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany
    J Biol Chem 272:10408-13. 1997
    ....
  38. ncbi Thiamine is a substrate of organic cation transporters in Caco-2 cells
    Clara Lemos
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
    Eur J Pharmacol 682:37-42. 2012
    ....
  39. ncbi Modulation of uptake of organic cationic drugs in cultured human colon adenocarcinoma Caco-2 cells by an ecto-alkaline phosphatase activity
    C Calhau
    Department of Biochemistry, Faculty of Medicine U38 FCT, University of Porto, Porto, Portugal
    J Cell Biochem 87:408-16. 2002
    ..9; P = 0.0014). We suggest that apical uptake of organic cations in Caco-2 cells is affected by phosphorylation/dephosphorylation mechanisms, and that ecto-ALP activity may be involved in this process...
  40. ncbi Differences between duodenal and jejunal rat alkaline phosphatase
    C Calhau
    Institute of Pharmacology and Therapeutics, Faculty of Medicine, Porto, Portugal
    Clin Biochem 33:571-7. 2000
    ....
  41. ncbi Modulation of insulin transport in rat brain microvessel endothelial cells by an ecto-phosphatase activity
    C Calhau
    Department of Biochemistry, Faculty of Medicine U38 FCT, 4200 319 Porto, Portugal
    J Cell Biochem 84:389-400. 2002
    ..82; P < 0.0001) in cultured rat brain endothelial cells, suggesting that insulin entry into the blood-brain barrier may be modulated through ALP...
  42. ncbi Estimation of the human intestinal permeability of butyltin species using the Caco-2 cell line model
    M A Azenha
    CIQ and Department of Chemistry, Faculty of Science, University of Porto, Rua do Campo Alegre, 687, 4169 007 Porto, Portugal
    Food Chem Toxicol 42:1431-42. 2004
    ....
  43. ncbi Intestinal uptake of MPP+ is differently affected by red and white wine
    R Monteiro
    Department of Biochemistry, Faculty of Medicine U 38, FCT, 4200 319 Porto, Portugal
    Life Sci 76:2483-96. 2005
    ....
  44. ncbi Effect of P-glycoprotein modulators on alkaline phosphatase activity in cultured rat hepatocytes
    C Calhau
    Department of Biochemistry, Faculty of Medicine, 4200 Porto, Portugal
    Cell Physiol Biochem 10:195-202. 2000
    ..The results show that all P-glycoprotein modulators tested were able to significantly affect the activity of hepatic-ALP. These effects on ALP activity may contribute to the modulation of P-glycoprotein activity by these drugs...
  45. ncbi Regulation of [(3)H]MPP(+) transport by phosphorylation/dephosphorylation pathways in RBE4 cells: role of ecto-alkaline phosphatase
    C Calhau
    Departamento de Bioquimica, Faculdade de Medicina 4200 319 Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 365:349-56. 2002
    ..A physiological role for ALP in the modulation of organic cation transport in the BBB is suggested...
  46. ncbi Modulation of MPP+ uptake by tea and some of its components in Caco-2 cells
    R Monteiro
    Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319, Porto, Portugal
    Naunyn Schmiedebergs Arch Pharmacol 372:147-52. 2005
    ..Although this constitutes only preliminary work and further studies are needed, tea should be included in the growing list of foodstuffs that have the potential to be involved in food-drug interactions...
  47. ncbi The effect of clotrimazole on energy substrate uptake and carcinogenesis in intestinal epithelial cells
    Pedro Goncalves
    Department of Biochemistry U38 FCT, University of Porto, Porto, Portugal
    Anticancer Drugs 23:220-9. 2012
    ..Moreover, stimulation of glucose uptake might be a compensation mechanism in response to the glycolysis inhibition caused by clotrimazole...
  48. ncbi Characterization of rat heart alkaline phosphatase isoenzymes and modulation of activity
    A Mota
    Departamento de Bioquímica U38 FCT, Faculdade de Medicina, Universidade do Porto, Porto, Portugal
    Braz J Med Biol Res 41:600-9. 2008
    ..ALP activity was inhibited by compounds used in the prevention of cardiovascular pathology. ALP manipulation in vivo may constitute an additional target for intervention in cardiovascular diseases...
  49. ncbi The release of 3H-1-methyl-4-phenylpyridinium from bovine adrenal chromaffin cells is modulated by somatostatin
    Laura Ribeiro
    Department of Biochemistry U38 FCT, Faculty of Medicine, 4200 319 Porto, Portugal
    Regul Pept 137:107-13. 2006
    ..These results, showing that somatostatin potentiates acetylcholine-induced [3H]MPP+ release, support the hypothesis that somatostatin may increase the release of catecholamines from adrenal medullary cells...
  50. ncbi Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine
    F Martel
    Department of Biochemistry (U38-FCT, Faculty of Medicine, 4200-319, Porto, Portugal
    Placenta 24:361-9. 2003
    ....
  51. ncbi Estimate of the digestibility, assimilability and intestinal permeability of butyltins occurring in wine
    M A Azenha
    CIQ UP and Department of Chemistry, Faculty of Science, University of Porto, Rua do Campo Alegre, 687, 4169 007 Porto, Portugal
    Food Chem Toxicol 46:767-73. 2008
    ..Additionally, the intestinal permeability of the three butyltins was also very low, the wine matrix possibly having a hindrance effect in a few cases...
  52. ncbi Molecular cloning and characterization of two novel transport proteins from rat kidney
    E Schomig
    Department of Pharmacology, University of Heidelberg, Germany
    FEBS Lett 425:79-86. 1998
    ..Characteristic signatures for the ASF family were identified...
  53. ncbi Comparison of the effect of cyclic AMP on the content and release of dopamine and 1-methyl-4-phenylpyridinium (Mpp+) in PC12 cells
    L Ribeiro
    Department of Biochemistry, and Institute of Pharmacology and Therapeutics (U38-FCT, Faculty of Medicine, 4200-319 Porto, Portugal
    Auton Autacoid Pharmacol 22:277-89. 2002
    ..8 In conclusion, cAMP, similarly to reserpine, increases the spontaneous release and decreases the KCl-induced release of [3H]-MPP+ and dopamine. This suggests that cAMP impairs the vesicular monoamine transporter...
  54. ncbi Large neutral amino acids supplementation in phenylketonuric patients
    J C Rocha
    Center of Medical Genetics Jacinto Magalhães INSA, Porto, Portugal
    J Inherit Metab Dis 32:472-80. 2009
    ....