Research Topics
Genomes and Genes | Ana C GomesSummaryAffiliation: University of Aveiro Country: Portugal Publications
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Detail Information
Publications
A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicansAna C Gomes
CESAM and Department of Biology, University of Aveiro, 3810 193 Aveiro, Portugal
Genome Biol 8:R206. 2007..Genetic code alterations have been reported in mitochondrial, prokaryotic, and eukaryotic cytoplasmic translation systems, but their evolution and how organisms cope and survive such dramatic genetic events are not understood...
Comparative genomics of wild type yeast strains unveils important genome diversityLaura Carreto
Departamento de Biologia and CESAM, Universidade de Aveiro, 3810 193 Aveiro, Portugal
BMC Genomics 9:524. 2008..This suggests that genome plasticity provides important genetic diversity upon which natural selection mechanisms can operate...
The yeast PNC1 longevity gene is up-regulated by mRNA mistranslationRaquel M Silva
Department of Biology and CESAM, University of Aveiro, Aveiro, Portugal
PLoS ONE 4:e5212. 2009....
The genetic code of the fungal CTG cladeManuel A S Santos
RNA Biology Laboratory, Department of Biology and CESAM, University of Aveiro, Campus de Santiago, 3810 193 Aveiro, Portugal
C R Biol 334:607-11. 2011..Here, we review the most recent results and concepts arising from the study of this codon reassignment and we highlight how its study is changing our views of the evolution of the genetic code...
Critical roles for a genetic code alteration in the evolution of the genus CandidaRaquel M Silva
Department of Biology and CESAM, University of Aveiro, Aveiro, Portugal
EMBO J 26:4555-65. 2007..This study highlights unanticipated roles for codon identity redefinition during the evolution of the genus Candida, and strongly suggests that genetic code alterations create genetic barriers that speed up speciation...
Parallel DNA pyrosequencing unveils new zebrafish microRNAsAna R Soares
RNA Biology Laboratory, Department of Biology and CESAM, University of Aveiro, Aveiro 3810 193, Portugal
BMC Genomics 10:195. 2009....
[The molecular mechanism of evolution of changes in the genetic code]Ana C Gomes
Mol Biol (Mosk) 40:634-9. 2006..Here, we review the molecular mechanism of CUG reassignment focusing on the structural change of the translational machinery and on the impact that such alteration had on the evolution of the Candida albicans genome...
