Gunnar R Mair

Summary

Affiliation: Faculdade de Medicina
Country: Portugal

Publications

  1. ncbi Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development
    Gunnar R Mair
    Leiden Malaria Research Group, Department of Parasitology, Centre for Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
    PLoS Pathog 6:e1000767. 2010
  2. ncbi A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes
    Joanna A M Braks
    Department of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre LUMC, Leiden, The Netherlands
    Nucleic Acids Res 36:1176-86. 2008
  3. ncbi Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology
    Shahid M Khan
    Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands
    Cell 121:675-87. 2005
  4. ncbi High efficiency transfection of Plasmodium berghei facilitates novel selection procedures
    Chris J Janse
    Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands
    Mol Biochem Parasitol 145:60-70. 2006
  5. ncbi Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility
    Eliane C Laurentino
    Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Cell Microbiol 13:1956-74. 2011

Collaborators

Detail Information

Publications5

  1. ncbi Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development
    Gunnar R Mair
    Leiden Malaria Research Group, Department of Parasitology, Centre for Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
    PLoS Pathog 6:e1000767. 2010
    ..Therefore, translational repression may offer avenues as a target for the generation of transmission blocking strategies and contribute to limiting the spread of malaria...
  2. ncbi A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes
    Joanna A M Braks
    Department of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre LUMC, Leiden, The Netherlands
    Nucleic Acids Res 36:1176-86. 2008
    ..These results demonstrate for the first time in a unicellular organism that the 5' or the 3'-UTR of TR-associated transcripts play an important and conserved role in mediating TR in female gametocytes...
  3. ncbi Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology
    Shahid M Khan
    Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands
    Cell 121:675-87. 2005
    ..By identification of gender-specific protein kinases and phosphatases and using targeted gene disruption of two kinases, new sex-specific regulatory pathways were defined...
  4. ncbi High efficiency transfection of Plasmodium berghei facilitates novel selection procedures
    Chris J Janse
    Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands
    Mol Biochem Parasitol 145:60-70. 2006
    ..The combination of enhanced transfection efficiency and a versatile rodent model provides a basis for the further development of novel tools for high throughput genome manipulation...
  5. ncbi Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility
    Eliane C Laurentino
    Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Cell Microbiol 13:1956-74. 2011
    ..Promoter swapping' is a powerful approach for the functional analysis of proteins in gametocytes (and beyond) that are essential during asexual blood-stage development...