Research Topics
Genomes and GenesSpecies | M OweckiSummaryAffiliation: University of Medical Sciences Country: Poland Publications
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Publications
Serum resistin concentrations are associated with HbA1c in obese non-diabetics, but not in obese diabetics: a cross-sectional human studyMaciej Owecki
Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Neuro Endocrinol Lett 32:349-53. 2011..Glycosylated hemoglobin (HbA1c) and resistin may be influenced by diabetes, but their associations remain unclear. We hypothesized that serum resistin might be parallel to Hb1c...
Serum adiponectin concentrations and their relationship with plasma lipids in obese diabetic and non-diabetic CaucasiansMaciej Owecki
Department of Endocrinology Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Neuro Endocrinol Lett 28:901-7. 2007..Despite early data, its relationship with obesity and diabetes has been recently questioned. Since plasma lipids influence diabetes and obesity, of concern is whether any associations between plasma lipids and adiponectin exist...
Serum adiponectin concentrations are not related to glycosylated hemoglobin levels (HbA1c) in obese diabetic and non-diabetic caucasiansM Owecki
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Exp Clin Endocrinol Diabetes 116:173-7. 2008..CONCLUSION: Concentrations of adiponectin were not correlated with levels of glycosylated hemoglobin in the diabetic and non-diabetic subjects examined...
Serum insulin levels and the degree of thyroid dysfunction in hypothyroid womenMaciej Owecki
Department of Endocrinology and Metabolism, University of Medical Sciences in Poznan, Poznan, Poland
Neuro Endocrinol Lett 29:137-40. 2008..In this study, we investigated serum serum insulin levels and their correlations with thyroid-stimulating hormone (TSH), free thyroxine (FT4) and free triiodothyronine (FT3) in hypothyroid women...
Circulating resistin levels are lower in hypothyroid women but independent from thyroid hormones concentrationsMaciej Owecki
Department of Endocrinology and Metabolism, University of Medical Sciences in Poznan, Poznan, Poland
Neuro Endocrinol Lett 29:131-6. 2008....
Fat tissue and adiponectin: new players in critical care?Maciej Owecki
Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences in Poznan, ul, Przybyszewskiego 49, 60 355 Poznan, Poland
Crit Care 13:174. 2009....
Leptin, soluble leptin receptors, free leptin index, and their relationship with insulin resistance and BMI: high normal BMI is the threshold for serum leptin increase in humansM Owecki
Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences in Poznan, Poznan, Poland
Horm Metab Res 42:585-9. 2010..Moreover, BMI threshold where leptin starts to increase is 24.6 kg/m (2), which is lower than the cutoff for overweight. Under the conditions, metabolic abnormalities may occur in parallel to much lower BMI levels as expected so far...
Serum resistin concentrations are higher in human obesity but independent from insulin resistanceM Owecki
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Exp Clin Endocrinol Diabetes 119:117-21. 2011..Correlations between resistin and BMI are present only in a mixed population but disappear in non obese and obese subjects when analyzed separately...
Serum resistin is related to plasma HDL cholesterol and inversely correlated with LDL cholesterol in diabetic and obese humansMaciej Owecki
Department of Endocrinology and Metabolism, University of Medical Sciences in Poznan, Poznan, Poland
Neuro Endocrinol Lett 31:673-8. 2010..Therefore, we put forward a hypothesis that serum lipids might be parallel to resistin, as they all reflect the metabolic status of obese humans...
Free leptin index as a marker for leptin action in diabetes and obesity: leptin and soluble leptin receptors relationship with HbA1cMaciej Owecki
Department of Endocrinology and Metabolism, University of Medical Sciences in Poznan, Poznan, Poland
Neuro Endocrinol Lett 31:679-83. 2010..Therefore, we put forward a hypothesis that serum leptin, sOBR and FLI might be parallel to Hb1c, as they all reflect the metabolic status...
The Y111 H (T415C) polymorphism in exon 3 of the gene encoding adiponectin is uncommon in Polish obese patientsM Owecki
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Horm Metab Res 39:797-800. 2007..The Y111 H adiponectin gene variant is uncommon in Polish obese subjects. Although we observed low adiponectin concentrations in Y111 H SNP heterozygote carriers, this finding was not confirmed by statistics...
Circulating leptin levels are not influenced by thyroid status in hypothyroid and euthyroid womenMaciej Owecki
Department of Endocrinology, Metabolism and Internal Diseases, University of Medical Sciences in Poznan, Ul Przybyszewskiego 49, 60 355 Poznan, Poland
Neuro Endocrinol Lett 28:417-21. 2007..Alterations in thyroid hormone levels are also associated with changes in body weight but the effect of thyroid hormone deficiency on serum leptin in humans is unclear...
Hypothyroidism has no impact on insulin sensitivity assessed with HOMA-IR in totally thyroidectomized patientsM Owecki
Katedra i Klinika Endokrynologii, Przemiany Materii i ChoróbWewnetrznych Akademii Medycznej w Poznaniu, Poznan, Poland
Acta Clin Belg 61:69-73. 2006..5426 and p=0.8175 in the examined group, and p=0.172 and p=0.4509 in the controls. CONCLUSION: Hypothyroidism has no impact on insulin sensitivity in the examined group...
Circulating serum adiponectin concentrations do not differ between obese and non-obese caucasians and are unrelated to insulin sensitivityM Owecki
Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences in Poznan, Poland
Horm Metab Res 39:25-30. 2007..These results lead to the conclusion that neither the concentrations of adiponectin differ between obese and non-obese humans, nor does any relationship between adiponectin concentration and insulin sensitivity exist...
Prolonged ventricular repolarization measured by corrected QT interval (QTc) in subclinical hyperthyroidismM Owecki
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
Horm Metab Res 38:44-7. 2006..001). QTc did not correlate with free thyroxin concentrations (p = 0.5084). Conclusion: Corrected QT intervals were significantly longer in patients with subclinical hyperthyroidism...
High prevalence of obesity in patients with non-functioning adrenal incidentalomasKamila Kolańska
Department of Endocrinology, Metabolism and Internal Diseases, University of Medical Sciences in Poznan, Poland
Neuro Endocrinol Lett 31:418-22. 2010..In contrast, the association between obesity and non-secreting adrenal incidentaloma has never been proven. Therefore, the aim of this study was to investigate this relationship in a large sample of patients...
[Insulin resistance assessed with HOMA-IR in hyperthyroid patients]Maciej Owecki
Katedra i Klinika Endokrynologii,
Pol Merkur Lekarski 19:617-20. 2005..5100 and p=0.5601 in the study group, and p=0.172 and p=0.4509 in the controls, respectively. CONCLUSION: Hyperthyroidism did not influence insulin resistance assessed with HOMA-IR model in vivo...
[Polymorphism of the sulfonylurea receptor gene in type 2 diabetes mellitus]Maciej Owecki
Katedra i Klinika Endokrynologii, Przemiany Materii i Chorób Wewnetrznych AM w Poznaniu
Pol Arch Med Wewn 109:143-8. 2003..Polymorphism of exon 22 of SUR1 gene appeared more frequent in diabetic than in non-diabetic subjects but this was statistically not significant...
[Molecular basis of oral hypoglycemic sulfonylurea action]Maciej Owecki
Katedra i Klinika Endokrynologii,
Pol Merkur Lekarski 15:445-8. 2003..The work discusses up to date views on the structure and function of sulfonylurea receptors and potassium channels as well as clinical implications of their disturbances...
[The mechanisms of inheritance of diabetes mellitus]Maciej Owecki
Kliniki Endokrynologii, , Akademii Medycznej w Poznaniu
Wiad Lek 57:682-5. 2004..The work presents contemporary views on genetic background of this disease. HLA phenotypes associated with type 1 diabetes as well as polygenic background of type 2 diabetes are discussed...
[Prolonged ventricular repolarization measured by QTc interval in hyperthyroidism]Maciej Owecki
Akademia Medyczna w Poznaniu, Katedra i Klinika Endokrynologii, Przemiany Materii i Chorbb Wewnetrznych
Pol Merkur Lekarski 19:24-7. 2005..Prolonged QTc is associated with increased risk for heart rythm disturbances and mortality. The aim of this study was to assess the effect of hyperthyroidism on heart repolarization, measured with QT corrected by Bazett's formula...
[Adiponectin and its role in the pathogenesis of obesity, diabetes mellitus and insulin resistance]Maciej Owecki
Akademia Medyczna w Poznaniu, Katedra i Klinika Endokrynologii, Przemiany Materii i Chorób Wewnetrznych
Pol Merkur Lekarski 20:355-7. 2006..Most importantly, the role of adiponectin in the body and the results of animal model experiments suggest the possible future use of adiponectin in the treatment of diabetes, atherosclerosis and obesity...
[Subclinical hypothyroidism influences ventricular repolarization measured by QTc interval]Maciej Owecki
Katedra i Klinika Endokrynologii, Przemiany Materii i Chorób Wewnetrznych, Akademii Medycznej w Poznaniu
Przegl Lek 63:185-7. 2006..3 vs. 73.7, SD +/- 13.58, NS). CONCLUSION: Corrected QT intervals were significantly prolonged in patients with subclinical hypothyroidism...
[Insulinoma of the pancreas--difficulties with imaging]Maciej Owecki
Katedra i Klinika Endokrynologii i Przemiany Materii AM w Poznaniu
Pol Arch Med Wewn 108:983-6. 2002..After surgery the symptoms alleviated completely. The patient with proper glucose levels was discharged in good health. The case supports high usefulness of intraoperative ultrasonography and surgeon's palpation...
