Research Topics
| Lucyna KepkaSummaryAffiliation: M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology Country: Poland Publications
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Detail Information
Publications
Chemoradiotherapy for rectal cancerKrzysztof Bujko
N Engl J Med 352:509-11; author reply 509-11. 2005
Results of the whole-brain radiotherapy for patients with brain metastases from lung cancer: the RTOG RPA intra-classes analysisLucyna Kepka
Department of Radiation Oncology, Memorial M Sklodowska Curie Cancer Center and Institute, Warsaw, Poland
Acta Oncol 44:389-98. 2005..RTOG RPA classes maintain their prognostic significance for patients with BM from lung cancer not participating in clinical trials...
Cardiopulmonary morbidity and quality of life in non-small cell lung cancer patients treated with or without postoperative radiotherapyLucyna Kepka
Department of Radiotherapy, The Maria Sklodowska Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland
Radiother Oncol 98:238-43. 2011..To prospectively assess the cardiopulmonary morbidity and quality of life in patients with non-small cell lung cancer (NSCLC) treated with postoperative radiotherapy (PORT) in comparison to those not receiving PORT...
Incidental irradiation of mediastinal and hilar lymph node stations during 3D-conformal radiotherapy for non-small cell lung cancerLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Acta Oncol 47:954-61. 2008..Minimum doses and volumes of LNS receiving 40 Gy or more (V40) were compared for omitted vs. limited+ extended ENI and limited vs. extended ENI...
[Postoperative radiotherapy for non-small cell lung cancer: evidence based data and clinical practice]Lucyna Kepka
Zaklad Teleradioterapii Centrum Onkologii Instytut im M Sklodowskiej Curie, Warszawa, Poland
Pneumonol Alergol Pol 75:256-61. 2007..The reasons of the common use of PORT, also for early stages of the disease, as shown by patterns of care surveys are presented in the light of the quality of surgery issues...
Delineation variation of lymph node stations for treatment planning in lung cancer radiotherapyLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, ul Roentgena 5, Warsaw, Poland
Radiother Oncol 85:450-5. 2007..To assess the variability among clinicians in the delineation of mediastinal and hilar lymph node stations (LNS) according to the published recommendations in the treatment planning of elective nodal irradiation for lung cancer...
Radiochemotherapy for lung cancer in developing countriesL Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, ul Roentgena 5, Warsaw, Poland
Clin Oncol (R Coll Radiol) 21:536-42. 2009..The availability of radiotherapy equipment is of major importance, as radiotherapy has a pivotal role in non-surgical treatment of lung cancer, especially in the developing world...
[Dilemmas in the curative treatment of lung cancer in elderly patients]Lucyna Kepka
Zakład Teleradioterapii Centrum Onkologii Instytutu im Marii Skłodowskiej Curie w Warszawie, 02 781 Warszawa
Pneumonol Alergol Pol 77:166-72. 2009..Some treatment options and modifications of standard strategies which are particularly promising in elderly patients, as VADS surgery, stereotactic radiotherapy or abbreviated treatment for SCLC, are presented...
Dose-per-fraction escalation of accelerated hypofractionated three-dimensional conformal radiotherapy in locally advanced non-small cell lung cancerLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
J Thorac Oncol 4:853-61. 2009..To determine the efficacy of accelerated hypofractionated three-dimensional conformal radiotherapy (3D-CRT) with dose-per-fraction escalation for treatment of stage III non-small cell lung cancer (NSCLC)...
Radiochemotherapy in small-cell lung cancerLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, ul Roentgena 5, 02 781 Warsaw, Poland
Expert Rev Anticancer Ther 9:1379-87. 2009..There is evidence that consolidation thoracic radiotherapy may be of value in extensive-disease SCLC. The recently initiated prospective trials may answer this question...
Combination of radiotherapy and chemotherapy in locally advanced NSCLCLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, ul Roentgena 5, 02 781 Warsaw, Poland
Expert Rev Anticancer Ther 9:1389-403. 2009..The new methods to improve treatment results, such as selection of proper strategies, incorporation of molecular agents into combined treatment and radiotherapy technique modifications are discussed...
Palliative thoracic radiotherapy for lung cancerLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, ul Roentgena 5, 02 781 Warsaw, Poland
Expert Rev Anticancer Ther 10:559-69. 2010....
Risk of isolated nodal failure for non-small cell lung cancer (NSCLC) treated with the elective nodal irradiation (ENI) using 3D-conformal radiotherapy (3D-CRT) techniques--a retrospective analysisLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Acta Oncol 47:95-103. 2008..To estimate retrospectively the rate of isolated nodal failures (INF) in NSCLC patients treated with the elective nodal irradiation (ENI) using 3D-conformal radiotherapy (3D-CRT)...
Resources and management strategies for the use of radiotherapy in the treatment of lung cancer in Central and Eastern European countries: results of an International Atomic Energy Agency (IAEA) surveyLucyna Kepka
Department of Radiotherapy, Maria Sklodowska Curie Memorial Cancer Centre and Institute of Oncology, ul Roentgena 5, 02 781 Warsaw, Poland
Lung Cancer 56:235-45. 2007..To assess resources and management strategies for the use of radiotherapy (RT) in the treatment of lung cancer in developing Central and Eastern European countries...
Prediction of mesorectal nodal metastases after chemoradiation for rectal cancer: results of a randomised trial: implication for subsequent local excisionKrzysztof Bujko
Department of Radiotherapy, Maria Skłodowska Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland
Radiother Oncol 76:234-40. 2005..For patients with rectal cancer treated with full thickness local excision the risk of mesorectal nodal metastases has to be very low. The aim was to assess this risk after preoperative radiotherapy in relation to pathological T-category...
Prospective evaluation of the palliative effect of whole-brain radiotherapy in patients with brain metastases and poor performance statusKatarzyna Komosinska
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Acta Oncol 49:382-8. 2010..The aim of this study was to determine whether WBRT has any benefit in terms of symptoms palliation in such patients. Evaluation of patients' preferences for WBRT, changes in performance and neurological status were secondary aims...
Association between pathologic response in metastatic lymph nodes after preoperative chemoradiotherapy and risk of distant metastases in rectal cancer: An analysis of outcomes in a randomized trialKrzysztof Bujko
Department of Radiotherapy, Maria Sklodowska Curie Memorial Cancer Center, Warsaw, Poland
Int J Radiat Oncol Biol Phys 67:369-77. 2007..4 Gy, 5-fluorouracil, leucovorin) with delayed surgery in a randomized trial for cT3-T4 low-lying rectal cancer. Despite the downstaging effect of chemoradiotherapy, similar long-term outcomes were observed in both groups...
Impact of [18F]fluorodeoxyglucose PET-CT staging on treatment planning in radiotherapy incorporating elective nodal irradiation for non-small-cell lung cancer: a prospective studyMilena Kolodziejczyk
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Int J Radiat Oncol Biol Phys 80:1008-14. 2011..To evaluate prospectively how positron emission tomography (PET) information changes treatment plans for non-small-cell lung cancer (NSCLC) patients receiving or not receiving elective nodal irradiation (ENI)...
Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: report of a randomised trialLucyna Pietrzak
Department of Radiotherapy, Maria Sklodowska Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland
Radiother Oncol 84:217-25. 2007..The aim of this report is to find out whether large doses per fraction of short-course schedule result in more severe anorectal and sexual dysfunction and quality of life (QoL) impairment...
Does incidental irradiation with doses below 50 gy effectively reduce isolated nodal failures in non-small-cell lung cancer: dose-response relationshipLucyna Kepka
Department of Radiotherapy, Cancer Center, Maria Sklodowska Curie Memorial Institute, Warsaw, Poland
Int J Radiat Oncol Biol Phys 73:1391-6. 2009..The endpoint was isolated nodal recurrence (INR) in stations that were initially negative...
Tumour regression grading in patients with residual rectal cancer after preoperative chemoradiationKrzysztof Bujko
Department of Radiotherapy, The Maria Sklodowska Curie Memorial Cancer Centre, 02 781 Warsaw, Poland
Radiother Oncol 95:298-302. 2010..To explore the utility of tumour regression grading (TRG, the amount of residual tumour cells in relation to extension of fibrosis) after chemoradiation of rectal cancer...
Designing targets for elective nodal irradiation in lung cancer radiotherapy: a planning studyLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Int J Radiat Oncol Biol Phys 73:1397-403. 2009....
Results of radiation therapy for unresected soft-tissue sarcomasLucyna Kepka
Department of Radiation Oncology, M Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
Int J Radiat Oncol Biol Phys 63:852-9. 2005..Definitive radiotherapy is uncommonly used in the management of soft-tissue sarcoma (STS). The purpose of the study was to evaluate the results of radiotherapy for unresected STSs treated in a single institution...
Does rectal cancer shrinkage induced by preoperative radio(chemo)therapy increase the likelihood of anterior resection? A systematic review of randomised trialsKrzysztof Bujko
Department of Radiotherapy, Maria Sklodowska Cuie Memorial Cancer Centre, Warsaw, Poland
Radiother Oncol 80:4-12. 2006..According to common conviction rectal tumour shrinkage after preoperative radio(chemo)therapy increases the likelihood of anterior resection (AR). In order to verify this belief, we performed a systematic review of randomised trials...
The potential impact of the tension of the pelvic muscles on set-up errors in radiotherapy for pelvic malignanciesKrzysztof Bujko
Department of Radiotherapy, Maria Sklodowska Curie Memorial Cancer Centre, Warsaw, Poland
Acta Oncol 43:740-3. 2004..This results in set-up inaccuracy, especially in the anterior-posterior direction, shielding block mispositioning and anal verge displacement...
Results of radiation therapy performed after unplanned surgery (without re-excision) for soft tissue sarcomasLucyna Kepka
Department of Radiation Oncology, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
J Surg Oncol 92:39-45. 2005..The risk for potential radiation therapy complications, however, must also be considered in the treatment decision...
Report from the International Atomic Energy Agency (IAEA) consultants' meeting on elective nodal irradiation in lung cancer: small-cell lung cancer (SCLC)Gregory M M Videtic
Department of Radiation Oncology, The Cleveland Clinic, Cleveland, OH 44195, USA
Int J Radiat Oncol Biol Phys 72:327-34. 2008....
Report from the International Atomic Energy Agency (IAEA) consultants' meeting on elective nodal irradiation in lung cancer: non-small-Cell lung cancer (NSCLC)Jose S A Belderbos
Department of Radiation Oncology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 72:335-42. 2008..The purpose of this report is to analyze the current status of ENI and to provide comprehensive in-depth analysis and guidance on how to generally approach this issue in NSCLC...
Chemoradiotherapy alone for rectal cancer: a word of cautionKrzysztof Bujko
Lancet Oncol 8:860-2; author reply 862-3. 2007
Distal intramural spread of rectal cancer after preoperative radiotherapy: the results of a multicenter randomized clinical studyEwa Chmielik
Department of Pathology, Maria Sklodowska-Curie Memorial Cancer Center, Gliwice, Poland
Int J Radiat Oncol Biol Phys 65:182-8. 2006..001). CONCLUSIONS: Approximately 1 out of 10 advanced rectal cancers after preoperative radiotherapy or radiochemotherapy was characterized by DIS of over 5 mm. No significant difference was seen in the length of DIS between the 2 groups...
[New radiotherapy techniques in the treatment of patients with craniopharyngioma: a report of two cases]Lucyna Kepka
, , , Centrum Onkologii-Instytut, Warszawa
Neurol Neurochir Pol 37:729-37; discussion 737-8. 2003..Two months after the treatment his complete recovery was confirmed by MRI. Benefits resulting from the use of more recent radiotherapy techniques in the management of craniopharyngioma are discussed...
