Katarzyna Tomala

Summary

Affiliation: Jagiellonian University
Country: Poland

Publications

  1. ncbi Molecular chaperones and selection against mutations
    Katarzyna Tomala
    Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30 387 Krakow, Poland
    Biol Direct 3:5. 2008
  2. ncbi Alleviation of deleterious effects of protein mutation through inactivation of molecular chaperones
    Katarzyna Tomala
    Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30 387, Krakow, Poland
    Mol Genet Genomics 280:409-17. 2008
  3. ncbi Interactions between stressful environment and gene deletions alleviate the expected average loss of fitness in yeast
    Lukasz Jasnos
    Institute of Environmental Sciences, Jagiellonian University, 30387 Krakow, Poland
    Genetics 178:2105-11. 2008
  4. ncbi Why molecular chaperones buffer mutational damage: a case study with a yeast Hsp40/70 system
    Joanna Bobula
    Institute of Environmental Sciences, Jagiellonian University, Poland
    Genetics 174:937-44. 2006

Collaborators

  • Ryszard Korona
  • Lukasz Jasnos
  • Joanna Bobula
  • Dorota Paczesniak
  • Elzbieta Jez
  • Dominika M Wloch
  • Rhona H Borts

Detail Information

Publications4

  1. ncbi Molecular chaperones and selection against mutations
    Katarzyna Tomala
    Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30 387 Krakow, Poland
    Biol Direct 3:5. 2008
    ..This would allow for the accumulation of genetic variation which could then be exposed during environmental perturbation and facilitate rapid adaptation...
  2. ncbi Alleviation of deleterious effects of protein mutation through inactivation of molecular chaperones
    Katarzyna Tomala
    Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30 387, Krakow, Poland
    Mol Genet Genomics 280:409-17. 2008
    ..We suggest that under non-stressful conditions, molecular chaperones are tuned to support folding of native proteins, but not that of mutated ones...
  3. ncbi Interactions between stressful environment and gene deletions alleviate the expected average loss of fitness in yeast
    Lukasz Jasnos
    Institute of Environmental Sciences, Jagiellonian University, 30387 Krakow, Poland
    Genetics 178:2105-11. 2008
    ..The effect of further damages tends to be weaker. This results in an average alleviating effect of interactions between stressful environment and gene deletions and among gene deletions...
  4. ncbi Why molecular chaperones buffer mutational damage: a case study with a yeast Hsp40/70 system
    Joanna Bobula
    Institute of Environmental Sciences, Jagiellonian University, Poland
    Genetics 174:937-44. 2006
    ..A plausible role of chaperones is to stabilize genetic networks, thus making them more tolerant to malfunctioning of their constituents...