E Roemer

Summary

Affiliation: Philip Morris Research Laboratories

Publications

  1. ncbi Chemical composition, cytotoxicity and mutagenicity of smoke from US commercial and reference cigarettes smoked under two sets of machine smoking conditions
    E Roemer
    PHILIP MORRIS Research Laboratories GmbH formerly INBIFO Institut fuer biologische Forschung, Fuggerstrasse 3, D 51149 Cologne, Germany
    Toxicology 195:31-52. 2004
  2. ncbi SKH-1 mouse skin painting: a short-term assay to evaluate the tumorigenic activity of cigarette smoke condensate
    E Roemer
    Philip Morris International R and D, Philip Morris Products SA, Neuchatel, Switzerland
    Toxicol Lett 192:155-61. 2010
  3. ncbi Scientific assessment of the use of sugars as cigarette tobacco ingredients: a review of published and other publicly available studies
    Ewald Roemer
    Philip Morris International Management S A, Operations Technical Services, Neuchatel, Switzerland
    Crit Rev Toxicol 42:244-78. 2012
  4. ncbi Limitations of cigarette machine smoking regimens
    E Roemer
    Philip Morris International, OTS, Rue des Usines 90, 2000 Neuchatel, Switzerland
    Toxicol Lett 203:20-7. 2011
  5. ncbi Cytotoxicity, mutagenicity, and tumorigenicity of mainstream smoke from three reference cigarettes machine-smoked to the same yields of total particulate matter per cigarette
    E Roemer
    Philip Morris International R and D, Quai Jeanrenaud 5, 2000 Neuchatel, Switzerland
    Food Chem Toxicol 47:1810-8. 2009
  6. ncbi Reduced toxicological activity of cigarette smoke by the addition of ammonium magnesium phosphate to the paper of an electrically heated cigarette: smoke chemistry and in vitro cytotoxicity and genotoxicity
    E Roemer
    Philip Morris Products S A, PMI Research and Development, 2000 Neuchatel, Switzerland
    Toxicol In Vitro 22:671-81. 2008
  7. ncbi Toxicological evaluation of an electrically heated cigarette. Part 3: Genotoxicity and cytotoxicity of mainstream smoke
    F J Tewes
    Philip Morris Research Laboratories, Fuggerstrasse 3, D 51149 Köln, Germany
    J Appl Toxicol 23:341-8. 2003
  8. ncbi The mouse lymphoma thymidine kinase assay for the assessment and comparison of the mutagenic activity of cigarette mainstream smoke particulate phase
    H Schramke
    Philip Morris Research Laboratories, Fuggerstrasse 3, D 51149 Cologne, Germany
    Toxicology 227:193-210. 2006
  9. ncbi Toxicological evaluation of an electrically heated cigarette. Part 2: Chemical composition of mainstream smoke
    R Stabbert
    Philip Morris Research Laboratories, Fuggerstrasse 3, D 51149 Köln, Germany
    J Appl Toxicol 23:329-39. 2003
  10. ncbi Evaluation of the potential effects of ingredients added to cigarettes. Part 3: in vitro genotoxicity and cytotoxicity
    E Roemer
    INBIFO Institut für biologische Forschung, 3, D 51149 Köln, Fuggerstr, Germany
    Food Chem Toxicol 40:105-11. 2002

Detail Information

Publications11

  1. ncbi Chemical composition, cytotoxicity and mutagenicity of smoke from US commercial and reference cigarettes smoked under two sets of machine smoking conditions
    E Roemer
    PHILIP MORRIS Research Laboratories GmbH formerly INBIFO Institut fuer biologische Forschung, Fuggerstrasse 3, D 51149 Cologne, Germany
    Toxicology 195:31-52. 2004
    ..At the same TPM yield, the smoke constituent concentrations and in vitro toxicity were similar for low- and high-yield cigarettes...
  2. ncbi SKH-1 mouse skin painting: a short-term assay to evaluate the tumorigenic activity of cigarette smoke condensate
    E Roemer
    Philip Morris International R and D, Philip Morris Products SA, Neuchatel, Switzerland
    Toxicol Lett 192:155-61. 2010
    ..The results obtained with the SKH-1 mouse strain suggest its usefulness in the short-term skin painting assay for the comparative investigation of the tumorigenic activity of different CSCs...
  3. ncbi Scientific assessment of the use of sugars as cigarette tobacco ingredients: a review of published and other publicly available studies
    Ewald Roemer
    Philip Morris International Management S A, Operations Technical Services, Neuchatel, Switzerland
    Crit Rev Toxicol 42:244-78. 2012
    ..In conclusion, thorough examination of the data available suggests that the use of sugars as ingredients in cigarette tobacco does not increase the inherent risk and harm of cigarette smoking...
  4. ncbi Limitations of cigarette machine smoking regimens
    E Roemer
    Philip Morris International, OTS, Rue des Usines 90, 2000 Neuchatel, Switzerland
    Toxicol Lett 203:20-7. 2011
    ..The type of smoking regimen has to be carefully considered and aligned to the underlying question. Depending on the question a combination of the reviewed regimens or even other approaches might be appropriate...
  5. ncbi Cytotoxicity, mutagenicity, and tumorigenicity of mainstream smoke from three reference cigarettes machine-smoked to the same yields of total particulate matter per cigarette
    E Roemer
    Philip Morris International R and D, Quai Jeanrenaud 5, 2000 Neuchatel, Switzerland
    Food Chem Toxicol 47:1810-8. 2009
    ..More intensive smoking conditions were associated with lower in vitro and in vivo activity per gram of TPM. The strongest decrease, and the tightest correlation, in this regard was observed for dermal tumorigenicity (tumor incidence)...
  6. ncbi Reduced toxicological activity of cigarette smoke by the addition of ammonium magnesium phosphate to the paper of an electrically heated cigarette: smoke chemistry and in vitro cytotoxicity and genotoxicity
    E Roemer
    Philip Morris Products S A, PMI Research and Development, 2000 Neuchatel, Switzerland
    Toxicol In Vitro 22:671-81. 2008
    ..In the study presented here, in vitro assays were used as quantitative tools to investigate toxicity-related mechanisms...
  7. ncbi Toxicological evaluation of an electrically heated cigarette. Part 3: Genotoxicity and cytotoxicity of mainstream smoke
    F J Tewes
    Philip Morris Research Laboratories, Fuggerstrasse 3, D 51149 Köln, Germany
    J Appl Toxicol 23:341-8. 2003
    ..When calculated on a per cigarette basis, the cytotoxicity of both the TPM fraction and the water-solubles in the gas/vapor phase of smoke from the EHC was ca. 80% lower relative to the 1R4F...
  8. ncbi The mouse lymphoma thymidine kinase assay for the assessment and comparison of the mutagenic activity of cigarette mainstream smoke particulate phase
    H Schramke
    Philip Morris Research Laboratories, Fuggerstrasse 3, D 51149 Cologne, Germany
    Toxicology 227:193-210. 2006
    ..These results show that the MLA can be used to assess and compare the mutagenic activity of cigarette mainstream smoke particulate phase in the comprehensive toxicological assessment of cigarette smoke...
  9. ncbi Toxicological evaluation of an electrically heated cigarette. Part 2: Chemical composition of mainstream smoke
    R Stabbert
    Philip Morris Research Laboratories, Fuggerstrasse 3, D 51149 Köln, Germany
    J Appl Toxicol 23:329-39. 2003
    ....
  10. ncbi Evaluation of the potential effects of ingredients added to cigarettes. Part 3: in vitro genotoxicity and cytotoxicity
    E Roemer
    INBIFO Institut für biologische Forschung, 3, D 51149 Köln, Fuggerstr, Germany
    Food Chem Toxicol 40:105-11. 2002
    ..Within the sensitivity and specificity of the test systems, the in vitro mutagenicity and cytotoxicity of the cigarette smoke were not increased by the addition of the ingredients...
  11. ncbi Evaluation of the potential effects of ingredients added to cigarettes. Part 2: chemical composition of mainstream smoke
    K Rustemeier
    INBIFO Institut für biologische Forschung, Fuggerstr 3, D 51149, Koln, Germany
    Food Chem Toxicol 40:93-104. 2002
    ..An overall assessment of our data suggests that these ingredients, when added to the tobacco, do not add to the toxicity of smoke, even at the elevated levels tested in this series of studies...