Association between serum testosterone concentration and collagen degradation fragments in men with type 2 diabetes mellitusMichiaki Fukui
Department of Endocrinology and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
Metabolism 56:1228-32. 2007
..In conclusion, serum free testosterone concentration correlated inversely with urinary NTx concentration, which may partly account for an observed link between osteoporosis and cardiovascular disease in men with type 2 diabetes mellitus...
High plasma 5-hydroxyindole-3-acetic acid concentrations in subjects with metabolic syndromeMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto
Diabetes Care 35:163-7. 2012
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Association between serum bioavailable testosterone concentration and the ratio of glycated albumin to glycated hemoglobin in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Diabetes Care 31:397-401. 2008
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Role of endogenous androgen against insulin resistance and athero- sclerosis in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Curr Diabetes Rev 3:25-31. 2007
..Because men with type 2 diabetes have relative hypogonadism, testosterone supplementation could decrease both insulin resistance and atherosclerosis...
Serum prostate-specific antigen levels in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Diabetes Care 31:930-1. 2008
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Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitusMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto 602 8566, Japan
Metabolism 57:625-9. 2008
..275, P=.0013) were independent determinants of logarithm of urinary albumin excretion. In conclusion, serum uric acid concentration is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitus...
Relationship between serum bilirubin and albuminuria in patients with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
Kidney Int 74:1197-201. 2008
..Our study shows that the serum bilirubin level is associated with microalbuminuria and subclinical atherosclerosis in patients with type 2 diabetes...
Plasma serotonin is a predictor for deterioration of urinary albumin excretion in men with type 2 diabetes mellitusMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kamigyo ku, Kyoto 602 8566, Japan
Metabolism 58:1076-9. 2009
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Eosinophil count is positively correlated with albumin excretion rate in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Clin J Am Soc Nephrol 4:1761-5. 2009
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Risk factors for development of diabetes mellitus, hypertension and dyslipidemiaMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Diabetes Res Clin Pract 94:e15-8. 2011
..When hypertension or dyslipidemia was present at baseline, hazard ratio (95% CI) of developing diabetes mellitus at year 5 is 3.014 (2.131-4.264) or 2.112 (1.520-2.936), respectively...
Relationship between low serum endogenous androgen concentrations and arterial stiffness in men with type 2 diabetes mellitusMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi Hirokoji, Kyoto, Japan
Metabolism 56:1167-73. 2007
..In conclusion, serum endogenous androgen concentrations are inversely associated with arterial stiffness determined by PWV in men with type 2 diabetes mellitus, which is true for men in general based on other works...
Association between urinary albumin excretion and plasma 5-hydroxyindole-3-acetic acid concentration in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
Diabetes Care 30:2649-51. 2007
Metabolic syndrome is not associated with markers of subclinical atherosclerosis, serum adiponectin and endogenous androgen concentrations in Japanese men with Type 2 diabetesM Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Diabet Med 24:864-71. 2007
..The aim of this study was to investigate the relationships between metabolic syndrome and markers of subclinical atherosclerosis, serum adiponectin and endogenous androgen concentrations in Japanese men with Type 2 diabetes...
Augmentation of central arterial pressure as a marker of atherosclerosis in patients with type 2 diabetesMichiaki Fukui
The Department of Endocrinology and Hematology, Osaka General Hospital of West Japan Railway Company, 1 2 22 Matsuzaki cho, Abeno Ku, Japan
Diabetes Res Clin Pract 59:153-61. 2003
..This simple, noninvasive determination would permit large-scale, early screening for atherosclerosis in patients with type 2 diabetes, who are at increased risk for cardiovascular disease...
Association between serum testosterone concentration and carotid atherosclerosis in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Hematology, Osaka General Hospital of West Japan Railway Company, Osaka, Japan
Diabetes Care 26:1869-73. 2003
..The aim of this study was to evaluate the relationship between serum testosterone concentration and carotid atherosclerosis as well as major cardiovascular risk factors in men with type 2 diabetes...
Idiopathic sudden hearing loss in patients with type 2 diabetesMichiaki Fukui
The Department of Endocrinology and Hematology, Osaka General Hospital of West Japan Railway Company, 1 2 22 Matsuzaki cho, Abeno Ku, 545 0053 Osaka, Japan
Diabetes Res Clin Pract 63:205-11. 2004
..Further studies are needed to determine which subgroups of diabetic patients are most likely to develop ISHL, which patients are predisposed to more severe hearing loss, and how various factors and treatments influence outcome...
Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentration in male patients with type 2 diabetes: a possible link between urinary albumin excretion and cardiovascular diseaseMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Diabetes Care 27:2893-7. 2004
..This raises the possibility of DHEA as a causal intermediate linking urinary albumin excretion to CVD...
Serum dehydroepiandrosterone sulfate concentration and carotid atherosclerosis in men with type 2 diabetesMichiaki Fukui
The Department of Endocrinology and Hematology, Osaka General Hospital of West Japan Railway Company, 1 2 22 Matsuzaki cho, Osaka 545 0053, Japan
Atherosclerosis 181:339-44. 2005
..0001) and of PS (beta = -0.301, P < 0.0001). In conclusion, serum DHEA-S concentration is negatively associated with carotid atherosclerosis determined by ultrasonographically evaluated IMT and PS in men with type 2 diabetes...
Association between alcohol consumption and serum dehydroepiandrosterone sulphate concentration in men with Type 2 diabetes: a link to decreased cardiovascular riskM Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Diabet Med 22:1446-50. 2005
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Low serum dehydroepiandrosterone sulfate concentration is a predictor for deterioration of urinary albumin excretion in male patients with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
Diabetes Res Clin Pract 73:47-50. 2006
..In conclusion, serum DHEA-S concentration was inversely correlated with changes in urinary albumin excretion, which may indicate causality in the increased CVD mortality in male patients with type 2 diabetes and low DHEA-S concentration...
Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentrations in women with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
Diabetes Care 30:1886-8. 2007
Five-item version of the international index of erectile function correlated with albuminuria and subclinical atherosclerosis in men with type 2 diabetesMichiaki Fukui
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
J Atheroscler Thromb 18:991-7. 2011
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Efficacy of glimepiride in patients with poorly controlled insulin-treated type 2 diabetes mellitusHiroyuki Ose
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Japan
Endocr J 52:563-9. 2005
..65 ng/ml, P = 0.0367). The number of hypoglycemic events did not differ between groups. Adding glimepiride to insulin therapy resulted in sustained improvement of glycemic control in patients with poorly controlled type 2 diabetes...
Direct and efficient production of ethanol from cellulosic material with a yeast strain displaying cellulolytic enzymesYasuya Fujita
Division of Molecular Science, Graduate School of Science and Technology of Kobe University, Japan
Appl Environ Microbiol 68:5136-41. 2002
..3% of the theoretical yield. This result indicates that efficient simultaneous saccharification and fermentation of cellulose to ethanol are carried out by a recombinant yeast cells displaying cellulolytic enzymes...