C J Timmer

Summary

Affiliation: Organon Laboratories Ltd

Publications

  1. ncbi Clinical pharmacokinetics of mirtazapine
    C J Timmer
    Department of Drug Metabolism and Kinetics, N V Organon, Oss, The Netherlands
    Clin Pharmacokinet 38:461-74. 2000
  2. ncbi Pharmacokinetics of etonogestrel and ethinylestradiol released from a combined contraceptive vaginal ring
    C J Timmer
    Department of Drug Metabolism and Kinetics, NV Organon, Oss, The Netherlands
    Clin Pharmacokinet 39:233-42. 2000
  3. ncbi Pharmacokinetics of mirtazapine and lithium in healthy male subjects
    J M Sitsen
    Clinical Development Department, NV Organon, Oss, The Netherlands
    J Psychopharmacol 14:172-6. 2000
  4. ncbi Concomitant use of mirtazapine and cimetidine: a drug-drug interaction study in healthy male subjects
    J M Sitsen
    N V Organon, Oss, The Netherlands
    Eur J Clin Pharmacol 56:389-94. 2000
  5. ncbi Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part II. Dose-proportionality and gonadotropin suppression after multiple doses of ganirelix in healthy female volunteers
    J J Oberyé
    Research and Development, NV Organon, Oss, The Netherlands
    Fertil Steril 72:1006-12. 1999
  6. ncbi Mirtazapine in combination with amitriptyline: a drug-drug interaction study in healthy subjects
    C Sennef
    NV Organon, PO Box 20, 5340 BH Oss, The Netherlands
    Hum Psychopharmacol 18:91-101. 2003
  7. ncbi Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part I. Absolute bioavailability of 0.25 mg of ganirelix after a single subcutaneous injection in healthy female volunteers
    J J Oberyé
    Research and Development, NV Organon, Oss, The Netherlands
    Fertil Steril 72:1001-5. 1999
  8. ncbi Pharmacokinetic evaluation of gepirone immediate-release capsules and gepirone extended-release tablets in healthy volunteers
    C J Timmer
    Department of Drug Metabolism and Kinetics, NV Organon, Molenstraat 110, P O Box 20, 5340 BH Oss, The Netherlands
    J Pharm Sci 92:1773-8. 2003

Detail Information

Publications8

  1. ncbi Clinical pharmacokinetics of mirtazapine
    C J Timmer
    Department of Drug Metabolism and Kinetics, N V Organon, Oss, The Netherlands
    Clin Pharmacokinet 38:461-74. 2000
    ..Although no concentration-effect relationship could be established, it was found that with therapeutic dosages of mirtazapine (15 to 45 mg/day), plasma concentrations range on average from 5 to 100 microg/L...
  2. ncbi Pharmacokinetics of etonogestrel and ethinylestradiol released from a combined contraceptive vaginal ring
    C J Timmer
    Department of Drug Metabolism and Kinetics, NV Organon, Oss, The Netherlands
    Clin Pharmacokinet 39:233-42. 2000
    ....
  3. ncbi Pharmacokinetics of mirtazapine and lithium in healthy male subjects
    J M Sitsen
    Clinical Development Department, NV Organon, Oss, The Netherlands
    J Psychopharmacol 14:172-6. 2000
    ..Extensive psychometric testing after the administration of mirtazapine did not reveal any differences on any tests in subjects on lithium and placebo, respectively...
  4. ncbi Concomitant use of mirtazapine and cimetidine: a drug-drug interaction study in healthy male subjects
    J M Sitsen
    N V Organon, Oss, The Netherlands
    Eur J Clin Pharmacol 56:389-94. 2000
    ..The objective of this study was to examine the pharmacokinetics and the tolerability/safety of mirtazapine and cimetidine separately and in combination following oral administration of multiple doses...
  5. ncbi Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part II. Dose-proportionality and gonadotropin suppression after multiple doses of ganirelix in healthy female volunteers
    J J Oberyé
    Research and Development, NV Organon, Oss, The Netherlands
    Fertil Steril 72:1006-12. 1999
    ..To assess the dose-proportionality and pharmacodynamic properties of multiple doses of ganirelix (Antagon/Orgalutran; NV Organon, Oss, the Netherlands)...
  6. ncbi Mirtazapine in combination with amitriptyline: a drug-drug interaction study in healthy subjects
    C Sennef
    NV Organon, PO Box 20, 5340 BH Oss, The Netherlands
    Hum Psychopharmacol 18:91-101. 2003
    ..Adding one drug to the other and substituting one drug by the other had no major effects on tolerability. Nevertheless, caution is warranted when combining amitriptyline and mirtazapine...
  7. ncbi Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part I. Absolute bioavailability of 0.25 mg of ganirelix after a single subcutaneous injection in healthy female volunteers
    J J Oberyé
    Research and Development, NV Organon, Oss, The Netherlands
    Fertil Steril 72:1001-5. 1999
    ..To assess the absolute bioavailability of ganirelix (Antagon/Orgalutran; NV Organon, Oss, the Netherlands) after a single SC injection...
  8. ncbi Pharmacokinetic evaluation of gepirone immediate-release capsules and gepirone extended-release tablets in healthy volunteers
    C J Timmer
    Department of Drug Metabolism and Kinetics, NV Organon, Molenstraat 110, P O Box 20, 5340 BH Oss, The Netherlands
    J Pharm Sci 92:1773-8. 2003
    ..This study revealed a reduction in the peak-to-trough fluctuations in plasma gepirone concentrations and maintenance of consistent plasma levels with gepirone-ER...