Research Topics
Genomes and Genes | Beate SkinningsrudSummaryAffiliation: University of Oslo Country: Norway Publications
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Publications
Mutation screening of PTPN22: association of the 1858T-allele with Addison's diseaseBeate Skinningsrud
Institute of Medical Genetics, University of Oslo, Department of Medical Genetics, Ullevaal University Hospital, Oslo, Norway
Eur J Hum Genet 16:977-82. 2008..In conclusion, the 1858T-allele is a PTPN22 genetic susceptibility factor for autoimmune AD. Other rare variants in PTPN22 do occur, and may also be involved in the pathogenesis...
Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiencyBeate Skinningsrud
Department of Medical Genetics, Ulleval University Hospital, University of Oslo, Kirkeveien 166, N 0407 Oslo, Norway
J Clin Endocrinol Metab 93:3310-7. 2008..In this study we aimed to investigate if loci found associated with common autoimmune diseases in recent genome-wide association studies also could be susceptibility loci for autoimmune Addison's disease (primary adrenal insufficiency)...
A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritisBeate Skinningsrud
Department of Medical Genetics, Oslo University Hospital, Ulleval, Kirkeveien 166, N 0407 Oslo, Norway
Ann Rheum Dis 69:1471-4. 2010....
X-linked congenital adrenal hypoplasia with hypogonadotropic hypogonadism caused by an inversion disrupting a conserved noncoding element upstream of the NR0B1 (DAX1) geneBeate Skinningsrud
Department of Medical Genetics, Oslo University Hospital, Ulleval, N 0407 Oslo, Norway
J Clin Endocrinol Metab 94:4086-93. 2009..OBJECTIVE/PATIENTS: Four males in a family were affected by AHCH. Our aim was to locate the genetic cause of their disease, knowing that they had no mutation in the obvious candidate gene, NR0B1...
Multiple loci in the HLA complex are associated with Addison's diseaseBeate Skinningsrud
Department of Medical Genetics, Oslo University Hospital, Ulleval, N 0407 Oslo, Norway
J Clin Endocrinol Metab 96:E1703-8. 2011..Recent evidence from other autoimmune diseases has suggested that class I-encoded HLA-A and HLA-B gene variants confer HLA-DRB1-DQA1-DQB1-independent effects on disease...
FOXP3 polymorphisms in type 1 diabetes and coeliac diseaseMarit Bjørnvold
Institute of Medical Genetics, Faculty Division Ulleval University Hospital, University of Oslo, Oslo, Norway
J Autoimmun 27:140-4. 2006..On the other hand, we were unable to reproduce our initial findings in the T1D case-control dataset (global p=0.6). Our results suggest that the tested FOXP3 markers do not have any major impact on susceptibility for these diseases...
CFTR gene mutations and asthma in the Norwegian Environment and Childhood Asthma studyMonica Cheng Munthe-Kaas
Department of Paediatrics, Woman Child Division, Ulleval University Hospital, NO 0407 Oslo, Norway
Respir Med 100:2121-8. 2006..Mutations in the CFTR gene result in derangements of mucociliary clearance. Homozygotes for CFTR mutations develop cystic fibrosis (CF), a disorder characterized mainly by lung and pancreas disease...
CTLA-4 polymorphisms in allergy and asthma and the TH1/ TH2 paradigmMonica Cheng Munthe-Kaas
Department of Pediatrics, Ulleval University Hospital, University of Oslo, Norway
J Allergy Clin Immunol 114:280-7. 2004..This region harbors the candidate gene cytotoxic T-lymphocyte antigen 4 (CTLA-4), an important regulator of T-cell activation and differentiation...
