Jørgen G Bramness

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi Testing for benzodiazepine inebriation--relationship between benzodiazepine concentration and simple clinical tests for impairment in a sample of drugged drivers
    Jørgen G Bramness
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
    Eur J Clin Pharmacol 59:593-601. 2003
  2. ncbi The risk of traffic accidents after prescriptions of carisoprodol
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, P O Box 4404, Nydalen, NO 0403 Oslo, Norway
    Accid Anal Prev 39:1050-5. 2007
  3. ncbi Clinical impairment of benzodiazepines--relation between benzodiazepine concentrations and impairment in apprehended drivers
    Jørgen G Bramness
    National Institute of Forensic Toxicology, P O Box 495, Sentrum, N 0105, Oslo, Norway
    Drug Alcohol Depend 68:131-41. 2002
  4. ncbi Flunitrazepam: psychomotor impairment, agitation and paradoxical reactions
    Jørgen G Bramness
    Norwegian Institute of Public Health, Department of Pharmacoepidemiology, PO Box 4404, Nydalen, NO 0403 Oslo, Norway
    Forensic Sci Int 159:83-91. 2006
  5. ncbi Carisoprodol intoxications and serotonergic features
    Jørgen G Bramness
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
    Clin Toxicol (Phila) 43:39-45. 2005
  6. ncbi Impairment due to intake of carisoprodol
    Jørgen G Bramness
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, 0403 Oslo, Norway
    Drug Alcohol Depend 74:311-8. 2004
  7. ncbi Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects?
    Jørgen G Bramness
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
    Pharmacogenetics 13:383-8. 2003
  8. ncbi [Buprenorphine as maintenance treatment in rehabilitation of heroin addicts]
    Jørgen G Bramness
    Statens rettstoksikologiske institutt Postboks 495 Sentrum 0105 Oslo
    Tidsskr Nor Laegeforen 122:2452-4. 2002
  9. ncbi Starting insomnia treatment: the use of benzodiazepines versus z-hypnotics. A prescription database study of predictors
    Anne M Hausken
    Division of Epidemiology, Norwegian Institute of Public Health, PO Box 4404, Nydalen, 0403 Oslo, Norway
    Eur J Clin Pharmacol 65:295-301. 2009
  10. ncbi An increased risk of road traffic accidents after prescriptions of lithium or valproate?
    Jørgen G Bramness
    Division of Epidemiology, Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Pharmacoepidemiol Drug Saf 18:492-6. 2009

Detail Information

Publications33

  1. ncbi Testing for benzodiazepine inebriation--relationship between benzodiazepine concentration and simple clinical tests for impairment in a sample of drugged drivers
    Jørgen G Bramness
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
    Eur J Clin Pharmacol 59:593-601. 2003
    ..The impact of single-dose intake in non-daily users of benzodiazepines on the clinical picture of inebriation was also studied...
  2. ncbi The risk of traffic accidents after prescriptions of carisoprodol
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, P O Box 4404, Nydalen, NO 0403 Oslo, Norway
    Accid Anal Prev 39:1050-5. 2007
    ..Carisoprodol, a drug used for acute lower back pain, may cause psychomotor impairment. We wanted to investigate if patients using carisoprodol had increased risk of being involved in a traffic accident...
  3. ncbi Clinical impairment of benzodiazepines--relation between benzodiazepine concentrations and impairment in apprehended drivers
    Jørgen G Bramness
    National Institute of Forensic Toxicology, P O Box 495, Sentrum, N 0105, Oslo, Norway
    Drug Alcohol Depend 68:131-41. 2002
    ..Whether this is true in a population of benzodiazepine users is uncertain. We studied the relationship in a population of suspected drugged drivers...
  4. ncbi Flunitrazepam: psychomotor impairment, agitation and paradoxical reactions
    Jørgen G Bramness
    Norwegian Institute of Public Health, Department of Pharmacoepidemiology, PO Box 4404, Nydalen, NO 0403 Oslo, Norway
    Forensic Sci Int 159:83-91. 2006
    ....
  5. ncbi Carisoprodol intoxications and serotonergic features
    Jørgen G Bramness
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
    Clin Toxicol (Phila) 43:39-45. 2005
    ..Since few laboratories routinely screen for carisoprodol it is important to keep this drug in mind when encountering intoxications displaying serotonergic symptoms...
  6. ncbi Impairment due to intake of carisoprodol
    Jørgen G Bramness
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, 0403 Oslo, Norway
    Drug Alcohol Depend 74:311-8. 2004
    ..Possible impairment could further be a product of the parent drug and/or the metabolite meprobamate. The present study aimed to investigate if carisoprodol had an impairing effect by it self...
  7. ncbi Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects?
    Jørgen G Bramness
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
    Pharmacogenetics 13:383-8. 2003
    ..Heterozygous individuals with the CYP2C19*1/*2 genotype have a reduced capacity for metabolizing carisoprodol, and should probably be regarded as intermediate metabolizers of this drug...
  8. ncbi [Buprenorphine as maintenance treatment in rehabilitation of heroin addicts]
    Jørgen G Bramness
    Statens rettstoksikologiske institutt Postboks 495 Sentrum 0105 Oslo
    Tidsskr Nor Laegeforen 122:2452-4. 2002
    ..Buprenorphine is used for maintenance treatment of opiate abusers...
  9. ncbi Starting insomnia treatment: the use of benzodiazepines versus z-hypnotics. A prescription database study of predictors
    Anne M Hausken
    Division of Epidemiology, Norwegian Institute of Public Health, PO Box 4404, Nydalen, 0403 Oslo, Norway
    Eur J Clin Pharmacol 65:295-301. 2009
    ..Drugs prescribed for the treatment of insomnia can be either benzodiazepine hypnotics or the newer z-hypnotics, zopiclone and zolpidem. This paper explores possible explanations for the choice made...
  10. ncbi An increased risk of road traffic accidents after prescriptions of lithium or valproate?
    Jørgen G Bramness
    Division of Epidemiology, Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Pharmacoepidemiol Drug Saf 18:492-6. 2009
    ..The objective of the present study was to examine whether the use of lithium or valproate increased the risk of being involved in traffic accidents...
  11. ncbi Road traffic accident risk related to prescriptions of the hypnotics zopiclone, zolpidem, flunitrazepam and nitrazepam
    Ingebjørg Gustavsen
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
    Sleep Med 9:818-22. 2008
    ..We wanted to investigate whether filling a prescription for zopiclone or zolpidem was associated with increased risk of road traffic accidents at a national population level. Nitrazepam and flunitrazepam were used as comparator drugs...
  12. ncbi The effect of scheduling and withdrawal of carisoprodol on prevalence of intoxications with the drug
    Gudrun Høiseth
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    Basic Clin Pharmacol Toxicol 105:345-9. 2009
    ..This, together with previous publications, indicates that the population reflected in our data uses regularly prescribed carisoprodol and, to a lesser degree, drug from an illegal street market...
  13. ncbi Impairment related to blood drug concentrations of zopiclone and zolpidem compared to alcohol in apprehended drivers
    Ingebjørg Gustavsen
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, PO Box 4404 Nydalen, 0403 Oslo, Norway
    Accid Anal Prev 41:462-6. 2009
    ..We compared these groups of drivers to a group suspected of alcohol-related impairment...
  14. ncbi The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects
    Jørgen G Bramness
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, P O Box 4404, Nydalen, 0403, Oslo, Norway
    Eur J Clin Pharmacol 61:499-506. 2005
    ..Impairing effects on psychomotor coordination and feelings of sedation were studied by comparing IMs with EMs following their ingestion of a single dose of 700 mg carisoprodol...
  15. ncbi Minor increase in risk of road traffic accidents after prescriptions of antidepressants: a study of population registry data in Norway
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
    J Clin Psychiatry 69:1099-103. 2008
    ..The objective of the present study was to examine whether the use of antidepressants by drivers increased the risk of being involved in traffic accidents...
  16. ncbi Benzodiazepine use in all alcohol consumers predicts use of opioids in patients 20 years later--a follow-up study of 13,390 men and women aged 40-42 years
    Svetlana Skurtveit
    Division of Epidemiology, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway
    Pharmacoepidemiol Drug Saf 17:926-933. 2008
    ..To evaluate the effect of the consumption of benzodiazepines at age 40-42 years on prescription of opioids later in life...
  17. ncbi The use of lithium, valproate or lamotrigine for psychiatric conditions in children and adolescents in Norway 2004-2007 - a prescription database study
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, NO 0881 Oslo, Norway
    J Affect Disord 117:208-11. 2009
    ..Our study aimed to explore how common the use of lithium, valproate and lamotrigine in psychiatric conditions in children and adolescents in Norway and to describe concomitant use of other psychotropic drugs...
  18. ncbi Carisoprodol use and abuse in Norway: a pharmacoepidemiological study
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Br J Clin Pharmacol 64:210-8. 2007
    ..Carisoprodol was developed to create a drug with less potential for abuse than meprobamate. However, case reports have established carisoprodol as a drug of abuse. This paper explores the extent of potential abuse of this drug in Norway...
  19. ncbi Impairment due to cannabis and ethanol: clinical signs and additive effects
    Jørgen G Bramness
    Norwegian Centre for Addiction Research, University of Oslo, Oslo, Norway
    Addiction 105:1080-7. 2010
    ..The purpose of this study was to see how different clinical tests and observations were related to blood THC concentrations and to determine whether the combined influence of THC and ethanol was different from either drug alone...
  20. ncbi Use of lithium in the adult populations of Denmark, Norway and Sweden
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    J Affect Disord 118:224-8. 2009
    ..The national prescription databases in Denmark, Norway and Sweden may help provide more reliable information on the epidemiology of lithium use...
  21. ncbi Psychotropic drug use among persons with mental distress symptoms: a population-based study in Norway
    Anne M Hausken
    Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Scand J Public Health 35:356-64. 2007
    ..To explore psychotropic drug use in the general population and in particular among non-institutionalized persons with mental distress symptoms...
  22. ncbi Benzodiazepine prescription for patients in opioid maintenance treatment in Norway
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, PO Box 4404, Nydalen, 0403 Oslo, Norway
    Drug Alcohol Depend 90:203-9. 2007
    ..Previous research has used interview or urine analysis to assess benzodiazepine use. In this study a prescription database was applied...
  23. ncbi Carisoprodol intoxications: a retrospective study of forensic autopsy material from 1992-2003
    Gudrun Høiseth
    Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway
    Int J Legal Med 121:403-9. 2007
    ..There were, however, only a small number of cases where the cause of death can be attributed to use of carisoprodol alone...
  24. ncbi Frequency and irregularity of heart rate in drivers suspected of driving under the influence of cannabis
    Hassan Z Khiabani
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Post Office Box 4404 Nydalen, 0403 Oslo Norway
    Eur J Intern Med 19:608-12. 2008
    ..We also compared THC-positive drivers with a regular pulse with THC-positive drivers with an irregular pulse...
  25. ncbi Prescription drug use among fathers and mothers before and during pregnancy. A population-based cohort study of 106,000 pregnancies in Norway 2004-2006
    Anders Engeland
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Br J Clin Pharmacol 65:653-60. 2008
    ..In this registry-based study, we examined more than 100,000 Norwegian pregnancies and described the drug prescription pattern of both fathers and mothers around conception and during pregnancy (mothers)...
  26. ncbi Relationship between THC concentration in blood and impairment in apprehended drivers
    Hassan Z Khiabani
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, Oslo, Norway
    Traffic Inj Prev 7:111-6. 2006
    ..The main purpose of the present study was to investigate whether a physician's judgment on impairment in a real-life setting among suspected drugged drivers, was related to blood THC concentration...
  27. ncbi An increased risk of motor vehicle accidents after prescription of methadone
    Jørgen G Bramness
    Norwegian Centre for Addiction Research, University of Oslo, Oslo, Norway
    Addiction 107:967-72. 2012
    ..To investigate whether exposure to methadone affects the risk of motor vehicle accident with personal injury...
  28. ncbi The use and potential abuse of anticholinergic antiparkinson drugs in Norway: a pharmacoepidemiological study
    Pål Gjerden
    Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Br J Clin Pharmacol 67:228-33. 2009
    ..Patients with psychotic conditions have a high prevalence of abuse of drugs, including anticholinergic antiparkinson drugs...
  29. ncbi Addiction research centres and the nurturing of creativity The Norwegian Centre for Addiction Research (SERAF)
    Jørgen G Bramness
    Norwegian Centre for Addiction Research, University of Oslo, Oslo, Norway
    Addiction 106:1381-5. 2011
    ....
  30. ncbi Comparison of drug concentrations in blood and oral fluid collected with the Intercept sampling device
    Hallvard Gjerde
    Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
    J Anal Toxicol 34:204-9. 2010
    ..1 amphetamine, 2.9 methamphetamine, 5.4 codeine, 1.9 morphine, and 4.7 tetrahydrocannabinol. The correlation coefficients between drug concentrations in oral fluid and blood ranged from 0.15 to 0.96 for the six most prevalent drugs...
  31. ncbi Does Pregabalin (Lyrica(®) ) Help Patients Reduce their Use of Benzodiazepines? A Comparison with Gabapentin using the Norwegian Prescription Database
    Jørgen G Bramness
    Norwegian Centre for Addiction Research, University of Oslo, Oslo, Norway Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway Department of Laboratory Medicine, Children s and Women s Health, Norwegian University of Science and Technology, Trondheim, Norway Department of Public Health and Primary Health Care University of Bergen, Bergen, Norway
    Basic Clin Pharmacol Toxicol 107:883-6. 2010
    ..This study shows that some patients reduced their use of benzodiazepines substantially after starting pregabalin...
  32. ncbi The sales of antidepressants and suicide rates in Norway and its counties 1980-2004
    Jørgen G Bramness
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    J Affect Disord 102:1-9. 2007
    ..Suicide is a major public health problem and depression is among the most important risk factors for suicide. Treatment of depression might prevent suicide. To study this hypothesis further we conducted an ecological study...