Research Topics
| K H OrstavikSummaryCountry: Norway Publications
| Collaborators
|
Detail Information
Publications
Severe craniofacial malformations and deglutition dysfunction in a brother and sister: new syndrome?K H Orstavik
Department of Medical Genetics, Ulleval Hospital, Oslo, Norway
Am J Med Genet 78:260-2. 1998..This may be an autosomal recessive or dominant trait with gonadal mosaicism in one of the parents...
X chromosome inactivation in carriers of Barth syndromeK H Orstavik
Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
Am J Hum Genet 63:1457-63. 1998..Since BTHS also shows great clinical variation within families, additional factors are likely to influence the expression of the phenotype. Such factors may also influence the selection mechanism in carriers...
Absence of correlation between X chromosome inactivation pattern and plasma concentration of factor VIII and factor IX in carriers of haemophilia A and BK H Orstavik
Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
Thromb Haemost 83:433-7. 2000..We conclude that the wide range in plasma concentration of factor VIII and factor IX in haemophilia A and B carriers cannot in general be explained by the X chromosome inactivation pattern in peripheral blood cells...
[Gene therapy for monogenic inherited diseases]K H Ørstavik
Avdeling for medisinsk genetikk Rikshospitalet 0027 Oslo
Tidsskr Nor Laegeforen 121:349-50. 2001..Most monogenic disorders are severe and have no cure. Gene therapy will therefore often be the only possible treatment...
X-inactivation patterns in carriers of X-linked myotubular myopathyM Kristiansen
Department of Medical Genetics, Institute of Medical Genetics, University of Oslo, Oslo, Norway
Neuromuscul Disord 13:468-71. 2003..Thus, there was a tendency for females with a more severe phenotype to have a skewed pattern of X inactivation, while females with an intermediate phenotype had a random pattern of X-inactivation...
Sibs with Ritscher-Schinzel (3C) syndrome and anal malformationsK H Orstavik
Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
Am J Med Genet 75:300-3. 1998..Anal anomalies have not been previously reported as a component manifestation of the disorder. The occurrence of 3 affected sibs in a consanguineous family confirms autosomal recessive inheritance...
High frequency of skewed X inactivation in young breast cancer patientsM Kristiansen
Institute of Medical Genetics, University of Oslo, Oslo, Norway
J Med Genet 39:30-3. 2002....
Increased skewing of X chromosome inactivation with age in both blood and buccal cellsG P S Knudsen
Department of Medical Genetics, Faculty Division, Rikshospitalet, University of Oslo, Oslo, Norway
Cytogenet Genome Res 116:24-8. 2007....
