Research Topics
Species | P E OlumeseSummaryAffiliation: University of Ibadan Country: Nigeria Publications
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Detail Information
Publications
Comparative efficacy of intramuscular artemether and intravenous quinine in Nigerian children with cerebral malariaP E Olumese
Department of Clinical Pharmacology, University College Hospital, Ibadan, Nigeria
Acta Trop 73:231-6. 1999..Artemether represents an important option in the management of cerebral malaria in Nigeria especially in rural areas where facilities for intravenous administration may not yet be optimal...
Neurological features of cerebral malaria in Nigerian childrenP E Olumese
Department of Clinical Pharmacology, University College Hospital, Ibadan, Nigeria
Ann Trop Paediatr 19:321-5. 1999..Careful clinical examination of such children is essential as neurological features of the condition may provide a clue to prognosis...
Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian childrenP E Olumese
Department of Clinical Pharmacology, University College Hospital, Ibadan, Nigeria
Trans R Soc Trop Med Hyg 96:418-20. 2002..The implication of this for antimalarial treatment policy is discussed...
Complexity of the msp2 locus and the severity of childhood malaria, in south-western NigeriaO K Amodu
Institute of Child Health, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria
Ann Trop Med Parasitol 102:95-102. 2008..It therefore appears that msp2 genotypes are associated with asymptomatic carriage and that children with mono-infections are more likely to develop severe malaria than children with polyinfection...
Genetic diversity of the msp-1 locus and symptomatic malaria in south-west NigeriaO K Amodu
College of Medicine, Institute of Child Health, University of Ibadan, Ibadan, Nigeria
Acta Trop 95:226-32. 2005..Our findings show that the presence of the K1 and MAD20 alleles was significantly associated with ASM and consequently a reduced risk of developing the symptomatic disease...
The influence of individual preventive measures on the clinical severity of malaria among Nigerian childrenO K Amodu
College of Medicine, University of Ibadan, Ibadan, Nigeria
Acta Trop 97:370-2. 2006
The clinical manifestations of cerebral malaria among Nigerian children with the sickle cell traitP E Olumese
Department of Clinical Pharmacology, College of Medicine, University College Hospital, Ibadan, Nigeria
Ann Trop Paediatr 17:141-5. 1997..It is concluded that the clinical manifestations of cerebral malaria are essentially similar in children with haemoglobins AS and AA but the former have higher transfusion needs and are less likely to die...
Intraleucocytic malaria pigment and clinical severity of malaria in childrenO K Amodu
Department of Clinical Pharmacology, University College Hospital, Ibadan, Nigeria
Trans R Soc Trop Med Hyg 92:54-6. 1998..It is concluded that the pigment-containing neutrophil count is a simple marker of disease severity in childhood malaria in addition to the parasite count...
Anti-sickling potential of a Nigerian herbal formula (ajawaron HF) and the major plant component (Cissus populnea L. CPK)J O Moody
Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Nigeria
Phytother Res 17:1173-6. 2003..4% inhibition of sickling at the end of 180 min incubation when compared with the normal saline control. The maximum percentage inhibition of sickling exhibited by the p-hydroxybenzoic acid control was 46.0% at 90 min incubation...
Plasmodium falciparum malaria in south-west Nigerian children: is the polymorphism of ICAM-1 and E-selectin genes contributing to the clinical severity of malaria?O K Amodu
College of Medicine, Institute of Child Health, University of Ibadan, Ibadan, Nigeria
Acta Trop 95:248-55. 2005..Further studies of host loci are needed to further delineate which polymorphisms are associated with severe malaria and increase our knowledge of the biology of host-parasite interactions...
Low plasma bicarbonate predicts poor outcome of cerebral malaria in Nigerian childrenS Oguche
Department of Paediatrics, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria
West Afr J Med 21:276-9. 2002..Patients with these findings require prompt referral for adequate treatment in centres equipped to manage such critically ill patients...
