Research Topics
| Joanna M YoungSummaryCountry: New Zealand Publications
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Detail Information
Publications
Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failureChristopher H Strey
Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
Atherosclerosis 179:201-6. 2005..Further studies are required to determine whether coenzyme Q(10) reductions are limiting the maximum favourable effects of statin therapy on the microcirculation...
A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the metabolic syndromeJoanna M Young
Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, New Zealand
Am J Hypertens 25:261-70. 2012..Our aim was to examine the effects of adjunctive coenzyme Q(10) therapy on 24-h ambulatory blood pressure (BP) in subjects with the metabolic syndrome and inadequate BP control...
Comparative effects of enzogenol and vitamin C supplementation versus vitamin C alone on endothelial function and biochemical markers of oxidative stress and inflammation in chronic smokersJoanna M Young
Lipid and Diabetes Research Group, Christchurch Hospital, New Zealand
Free Radic Res 40:85-94. 2006..However, Enzogenol did demonstrate additional favourable effects on protein oxidative damage and fibrinogen levels...
Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgiaJoanna M Young
Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
Am J Cardiol 100:1400-3. 2007..47). In conclusion, coenzyme Q(10) supplementation did not improve statin tolerance or myalgia, although further studies are warranted...
Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failureJoanna M Young
Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
Eur J Heart Fail 10:463-6. 2008..Since statins upregulate eNOS and ameliorate endothelial dysfunction in non-ischaemic CHF, we hypothesized that this may be in part through modification of ADMA...
Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapyJoanna M Young
Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, Private Bag 4710, Christchurch 8011, New Zealand
Atherosclerosis 218:188-93. 2011....
Coenzyme Q10; an adjunctive therapy for congestive heart failure?Sarah L Molyneux
Biochemistry Unit, Canterbury Health Laboratories, Christchurch, New Zealand
N Z Med J 122:74-9. 2009..CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF...
