Gregory B Sands

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. ncbi Virtual sectioning of cardiac tissue relative to fiber orientation
    Gregory B Sands
    Bioengineering Institute, Department of Physiology, University of Auckland, Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 2008:226-9. 2008
  2. ncbi Automated extended volume imaging of tissue using confocal and optical microscopy
    G B Sands
    Bioengineering Institute, The University of Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 1:133-6. 2006
  3. ncbi The collagenous microstructure of cardiac ventricular trabeculae carneae
    G Sands
    Auckland Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Struct Biol 173:110-6. 2011
  4. ncbi Automated imaging of extended tissue volumes using confocal microscopy
    Gregory B Sands
    Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Microsc Res Tech 67:227-39. 2005
  5. ncbi Three distinct directions of intramural activation reveal nonuniform side-to-side electrical coupling of ventricular myocytes
    Bryan J Caldwell
    Auckland Bioengineering Institute, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Circ Arrhythm Electrophysiol 2:433-40. 2009
  6. ncbi Three-dimensional cardiac tissue image registration for analysis of in vivo electrical mapping
    Mark L Trew
    Auckland Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland Mail Centre, Auckland, 1142, New Zealand
    Ann Biomed Eng 39:235-48. 2011
  7. ncbi Surface imaging microscopy using an ultramiller for large volume 3D reconstruction of wax- and resin-embedded tissues
    Dane A Gerneke
    Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Microsc Res Tech 70:886-94. 2007
  8. ncbi Laminar arrangement of ventricular myocytes influences electrical behavior of the heart
    Darren A Hooks
    Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Circ Res 101:e103-12. 2007
  9. ncbi Experiment-specific models of ventricular electrical activation: construction and application
    Mark L Trew
    Auckland Bioengineering Institute, Department of Physiology, University of Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 2008:137-40. 2008
  10. ncbi Structure specific models of electrical function in the right atrial appendage
    Jichao Zhao
    Bioengineering Institute, The University of Auckland, 1142, Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 2008:145-8. 2008

Detail Information

Publications16

  1. ncbi Virtual sectioning of cardiac tissue relative to fiber orientation
    Gregory B Sands
    Bioengineering Institute, Department of Physiology, University of Auckland, Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 2008:226-9. 2008
    ..Images extracted from the image volume on curvilinear planes derived from these axes reveal a consistent view of myocardial architecture...
  2. ncbi Automated extended volume imaging of tissue using confocal and optical microscopy
    G B Sands
    Bioengineering Institute, The University of Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 1:133-6. 2006
    ..We have developed an imaging rig which supports both confocal and light microscopy, and utilizes a surface imaging approach to serially image embedded tissue blocks while maintaining alignment and registration of the image series...
  3. ncbi The collagenous microstructure of cardiac ventricular trabeculae carneae
    G Sands
    Auckland Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Struct Biol 173:110-6. 2011
    ..For specimens of dimensions typically used experimentally, there was no difference in average collagen content (6.03 ± 5.14%, n = 33) of preparations from the two ventricles...
  4. ncbi Automated imaging of extended tissue volumes using confocal microscopy
    Gregory B Sands
    Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Microsc Res Tech 67:227-39. 2005
    ....
  5. ncbi Three distinct directions of intramural activation reveal nonuniform side-to-side electrical coupling of ventricular myocytes
    Bryan J Caldwell
    Auckland Bioengineering Institute, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Circ Arrhythm Electrophysiol 2:433-40. 2009
    ..We present new experimental evidence that contradicts this view...
  6. ncbi Three-dimensional cardiac tissue image registration for analysis of in vivo electrical mapping
    Mark L Trew
    Auckland Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland Mail Centre, Auckland, 1142, New Zealand
    Ann Biomed Eng 39:235-48. 2011
    ..The methods are validated and techniques for identifying the preferred maps are proposed. Recorded electrical activation is shown to map reliably onto cardiac tissue structure using this registration method...
  7. ncbi Surface imaging microscopy using an ultramiller for large volume 3D reconstruction of wax- and resin-embedded tissues
    Dane A Gerneke
    Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Microsc Res Tech 70:886-94. 2007
    ..This understanding is essential for better analyses of the structural changes associated with different disease states, and the development of structure-based computer models of biological function...
  8. ncbi Laminar arrangement of ventricular myocytes influences electrical behavior of the heart
    Darren A Hooks
    Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Circ Res 101:e103-12. 2007
    ..More generally, the mechanisms governing the destabilization of coordinated electrical propagation into ventricular arrhythmia need to be evaluated in the light of this discovery...
  9. ncbi Experiment-specific models of ventricular electrical activation: construction and application
    Mark L Trew
    Auckland Bioengineering Institute, Department of Physiology, University of Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 2008:137-40. 2008
    ..Appropriate model conductivity parameters were deduced from measurements and used to replicate features of experimental recordings...
  10. ncbi Structure specific models of electrical function in the right atrial appendage
    Jichao Zhao
    Bioengineering Institute, The University of Auckland, 1142, Auckland, New Zealand
    Conf Proc IEEE Eng Med Biol Soc 2008:145-8. 2008
    ..The RAA was activated by applying a stimulus (150 microA/mm3, 5 ms) to the 27 grid points at the top of the CT. Despite the complex structure of the PM, RAA activation was relatively uniform...
  11. ncbi Three-dimensional transmural organization of perimysial collagen in the heart
    Adèle J Pope
    Department of Physiology, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
    Am J Physiol Heart Circ Physiol 295:H1243-H1252. 2008
    ..While myolaminae are the principal form of structural organization throughout most of the wall, they are not seen in the subepicardium, where perimysial collagen is present only as longitudinal cords...
  12. ncbi Modeling cardiac electrical activity at the cell and tissue levels
    Travis M Austin
    Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Ann N Y Acad Sci 1080:334-47. 2006
    ..Our models, which can incorporate ion channel models at the cell level into the reaction-diffusion equations at the tissue level, have enabled us to consider key hypotheses regarding discontinuous activation...
  13. ncbi An image-based model of atrial muscular architecture: effects of structural anisotropy on electrical activation
    Jichao Zhao
    Auckland Bioengineering Institute, Engineering Science, and Physiology, University of Auckland, Auckland, New Zealand and the School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom
    Circ Arrhythm Electrophysiol 5:361-70. 2012
    ..Conclusions- We have developed a structurally detailed, image-based model of atrial anatomy that provides deeper understanding of the role that myocyte architecture plays in normal and abnormal atrial electric function...
  14. ncbi Shock-induced transmembrane potential fields in a model of cardiac microstructure
    Mark Trew
    Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    J Cardiovasc Electrophysiol 16:1024. 2005
  15. ncbi Rapid construction of a patient-specific torso model from 3D ultrasound for non-invasive imaging of cardiac electrophysiology
    L K Cheng
    Bioengineering Institute, The University of Auckland, New Zealand
    Med Biol Eng Comput 43:325-30. 2005
    ..3 mm and obtain a quantitatively realistic activation sequence. The study demonstrates that it is possible rapidly to construct a geometric model that can then be used non-invasively to reconstruct an activation field map of the heart...
  16. ncbi Cardiac electrophysiology and tissue structure: bridging the scale gap with a joint measurement and modelling paradigm
    Mark L Trew
    Bioengineering Institute, The University of Auckland, New Zealand
    Exp Physiol 91:355-70. 2006
    ..Our models have enabled us to consider key hypotheses regarding discontinuous activation. We also consider the future developments of our intact tissue experimental programme...