Richard J Porter

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. ncbi Longitudinal assessment of neuropsychological function in major depression
    Katie M Douglas
    Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand
    Aust N Z J Psychiatry 43:1105-17. 2009
  2. ncbi Effects of the addition of remifentanil to propofol anesthesia on seizure length and postictal suppression index in electroconvulsive therapy
    Richard Porter
    Department of Psychological Medicine, University of Otago, Christchurch, New Zealand
    J ECT 24:203-7. 2008
  3. ncbi Prolactin response to fenfluramine in abstinent, alcohol-dependent patients
    Richard J Porter
    Department of Psychological Medicine, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand
    Addict Biol 13:380-5. 2008
  4. ncbi Tryptophan hydroxylase gene (TPH1) and peripheral tryptophan levels in depression
    Richard J Porter
    Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand
    J Affect Disord 109:209-12. 2008
  5. ncbi Effects of rapid tryptophan depletion on salivary cortisol in older people recovered from depression, and the healthy elderly
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, New Zealand, and Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK
    J Psychopharmacol 21:71-5. 2007
  6. ncbi Tryptophan and tyrosine availability and response to antidepressant treatment in major depression
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, P O Box 4345, Christchurch, New Zealand
    J Affect Disord 86:129-34. 2005
  7. ncbi Neuropsychological impairment in major depression: its nature, origin and clinical significance
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Aust N Z J Psychiatry 41:115-28. 2007
  8. ncbi Elevated prolactin responses to L-tryptophan infusion in medication-free depressed patients
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, New Zealand
    Psychopharmacology (Berl) 169:77-83. 2003
  9. ncbi Neuropsychological changes and treatment response in severe depression
    Katie M Douglas
    Department of Psychological Medicine, University of Otago Christchurch, PO Box 4345, Christchurch, New Zealand
    Br J Psychiatry 198:115-22. 2011
  10. ncbi Baseline prolactin and L-tryptophan availability predict response to antidepressant treatment in major depression
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, P O Box 4345, Christchurch, New Zealand
    Psychopharmacology (Berl) 165:216-21. 2003

Detail Information

Publications26

  1. ncbi Longitudinal assessment of neuropsychological function in major depression
    Katie M Douglas
    Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand
    Aust N Z J Psychiatry 43:1105-17. 2009
    ..With further methodologically sound research, the changes in neuropsychological function associated with treatment response may provide a means of evaluating different treatment strategies in major depression...
  2. ncbi Effects of the addition of remifentanil to propofol anesthesia on seizure length and postictal suppression index in electroconvulsive therapy
    Richard Porter
    Department of Psychological Medicine, University of Otago, Christchurch, New Zealand
    J ECT 24:203-7. 2008
    ..However, there are concerns that its anticonvulsant effect may interfere with the efficacy of ECT. We aimed to investigate the effects on seizure activity of the addition of the opiate remifentanil to propofol anesthesia for ECT...
  3. ncbi Prolactin response to fenfluramine in abstinent, alcohol-dependent patients
    Richard J Porter
    Department of Psychological Medicine, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand
    Addict Biol 13:380-5. 2008
    ..The reduced CORT response in abstinent alcoholics further supports evidence of hypofunction of the adrenocortical system in this group...
  4. ncbi Tryptophan hydroxylase gene (TPH1) and peripheral tryptophan levels in depression
    Richard J Porter
    Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand
    J Affect Disord 109:209-12. 2008
    ..Evidence suggests that hypothalamic and peripheral 5HT systems have a significant role in appetite regulation, possibly a homeostatic mechanism in regulating peripheral TRP levels...
  5. ncbi Effects of rapid tryptophan depletion on salivary cortisol in older people recovered from depression, and the healthy elderly
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, New Zealand, and Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK
    J Psychopharmacol 21:71-5. 2007
    ..However, they demonstrated reduced reactivity of the HPA axis compared to healthy subjects...
  6. ncbi Tryptophan and tyrosine availability and response to antidepressant treatment in major depression
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, P O Box 4345, Christchurch, New Zealand
    J Affect Disord 86:129-34. 2005
    ....
  7. ncbi Neuropsychological impairment in major depression: its nature, origin and clinical significance
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Aust N Z J Psychiatry 41:115-28. 2007
    ..Classification based on neuropsychological profile may, in fact, be useful. Further research should examine further the clinical importance of patterns of neuropsychological impairment...
  8. ncbi Elevated prolactin responses to L-tryptophan infusion in medication-free depressed patients
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, New Zealand
    Psychopharmacology (Berl) 169:77-83. 2003
    ..The greater prolactin response to l-tryptophan infusion in depressed subjects may be the result of an increase in dopamine receptor sensitivity, secondary to reduced dopamine levels...
  9. ncbi Neuropsychological changes and treatment response in severe depression
    Katie M Douglas
    Department of Psychological Medicine, University of Otago Christchurch, PO Box 4345, Christchurch, New Zealand
    Br J Psychiatry 198:115-22. 2011
    ..Some aspects of these functions may change during treatment and may be useful in assessing treatment response, even at an early stage of treatment...
  10. ncbi Baseline prolactin and L-tryptophan availability predict response to antidepressant treatment in major depression
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, P O Box 4345, Christchurch, New Zealand
    Psychopharmacology (Berl) 165:216-21. 2003
    ..It has been suggested that the PRF may predict response to different forms of treatment. Baseline cortisol, prolactin, and L-tryptophan ( L-TRP) availability may affect PRF and may also influence response to treatment...
  11. ncbi Effects of childhood experiences on cortisol levels in depressed adults
    Peter R Joyce
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Aust N Z J Psychiatry 41:62-5. 2007
    ..To evaluate the impact of childhood abuse and parental bonding on cortisol levels in depressed adults...
  12. ncbi Effects of rapid tryptophan depletion on salivary and plasma cortisol in Alzheimer's disease and the healthy elderly
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, University of Otago, New Zealand
    J Psychopharmacol 16:73-8. 2002
    ..We conclude that, in subjects with DAT and healthy elderly subjects, acute tryptophan depletion had no effect on cortisol secretion...
  13. ncbi Comparison of insulin resistance, metabolic syndrome and adiponectin in overweight bipolar patients taking sodium valproate and controls
    Jane L Elmslie
    Department of Psychological Medicine, University of Otago, Christchurch, New Zealand
    Aust N Z J Psychiatry 43:53-60. 2009
    ....
  14. ncbi Effects of acute tryptophan depletion on mood and cognitive functioning in older recovered depressed subjects
    Richard J Porter
    Dept of Psychological Medicine, P O Box 4345, Christchurch, New Zealand
    Am J Geriatr Psychiatry 13:607-15. 2005
    ..These risk factors are frequent in older recovered depressed people. The authors investigated the effects of ATD on mood and cognitive functioning in this group...
  15. ncbi The prolactin response to fenfluramine in depression: effects of melancholia and baseline cortisol
    Roger T Mulder
    Department of Psychological Medicine, Christchurch School of Medicine, Christchurch, New Zealand
    J Psychopharmacol 17:97-102. 2003
    ..However, the relationship between prolactin response to fenfluramine and baseline cortisol levels appeared to differ between these two subtypes of depression...
  16. ncbi Abnormal response to failure in unmedicated major depression
    Katie M Douglas
    Department of Psychological Medicine, University of Otago, Christchurch, New Zealand
    J Affect Disord 119:92-9. 2009
    ..That is, a rapid deterioration of performance after receiving feedback that an error was made on the previous task. We aimed to examine this phenomenon in unmedicated, depressed outpatients...
  17. ncbi Reversed diurnal variation in depression: associations with a differential antidepressant response, tryptophan: large neutral amino acid ratio and serotonin transporter polymorphisms
    Peter R Joyce
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    Psychol Med 35:511-7. 2005
    ..Although diurnal variation of mood is a widely recognized symptom of depression, the clinical, neurobiological and psychopharmacological significance of this symptom has not previously been reported...
  18. ncbi Neurocognitive impairment in drug-free patients with major depressive disorder
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, New Zealand
    Br J Psychiatry 182:214-20. 2003
    ..This is not attributable to the confounding effects of psychotropic medication and could therefore provide an objective marker of brain dysfunction in depression...
  19. ncbi Corticosteroid-serotonin interactions in depression: a review of the human evidence
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, Christchurch, New Zealand
    Psychopharmacology (Berl) 173:1-17. 2004
    ..It has been suggested that corticosteroid-serotonin interactions are central to the pathophysiology of depression. These interactions have been investigated in healthy and depressed humans, primarily using neuroendocrine techniques...
  20. ncbi The relationship between non-acute adolescent cannabis use and cognition
    Megan A Harvey
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, New Zealand
    Drug Alcohol Rev 26:309-19. 2007
    ..The results suggest that aspects of adolescent cognitive function are independently related to the frequency of cannabis use beyond acute intoxication...
  21. ncbi Recognition of disgusted facial expressions in severe depression
    Katie M Douglas
    Department of Psychological Medicine, University of Otago, PO Box 4345, Christchurch 8011, New Zealand
    Br J Psychiatry 197:156-7. 2010
    ..The depression group also displayed a specific deficit in the recognition of facial expressions of disgust, compared with controls. This may relate to impaired functioning of frontostriatal structures, particularly the basal ganglia...
  22. ncbi Characterizing mild cognitive impairment in Parkinson's disease
    John C Dalrymple-Alford
    Van der Veer Institute for Parkinson s and Brain Research, Christchurch, New Zealand
    Mov Disord 26:629-36. 2011
    ..Clinical dementia rating did not improve the relative identification of cognitively impaired and unimpaired nondementia PD patients...
  23. ncbi Carnitine does not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet
    Jane L Elmslie
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    Bipolar Disord 8:503-7. 2006
    ..The aim of this study was to determine whether l-carnitine supplementation improves weight loss outcomes in bipolar patients taking sodium valproate...
  24. ncbi The effects of sub-chronic administration of hydrocortisone on hormonal and psychological responses to L-tryptophan in normal male volunteers
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, Christchurch, New Zealand
    Psychopharmacology (Berl) 163:68-75. 2002
    ..More precise, non-neuroendocrine models of 5-HT(1A) receptor function are necessary to clarify this...
  25. ncbi Effects of hydrocortisone administration on cognitive function in the elderly
    Richard J Porter
    Department of Psychological Medicine, Christchurch School of Medicine, New Zealand
    J Psychopharmacol 16:65-71. 2002
    ..The elderly may be less sensitive to cognitive effects of short-term increases in cortisol levels, possibly due to an age-related downregulation of hippocampal glucocorticoid receptors...
  26. ncbi Neurocognitive function following remission in major depressive disorder: potential objective marker of response?
    Peter Gallagher
    School of Neurology, Neurobiology and Psychiatry, Newcastle University, Leazes Wing Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK
    Aust N Z J Psychiatry 41:54-61. 2007
    ..Neurocognitive deficits have been widely reported in patients with mood disorders. However, relatively little is known of the short-term trajectory of neurocognitive improvement once treatment has been initiated...