Research Topics
Species | Ryan L DavisSummaryAffiliation: University of Otago Country: New Zealand Publications
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Detail Information
Publications
Novel frameshift in the serum albumin gene results in analbuminemia through premature truncation and post translational modificationRyan L Davis
Molecular Pathology Laboratory, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand
Clin Biochem 41:1482-5. 2008..To identify the molecular lesion in a patient with analbuminemia...
A deep intronic mutation in FGB creates a consensus exonic splicing enhancer motif that results in afibrinogenemia caused by aberrant mRNA splicing, which can be corrected in vitro with antisense oligonucleotide treatmentRyan L Davis
Molecular Pathology Laboratory, Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
Hum Mutat 30:221-7. 2009....
Hypofibrinogenaemia associated with common gamma82Ala-->Gly mutation is not mediated by altered mRNA splicingStephen O Brennan
Molecular Pathology Laboratory, Canterbury Health Laboratories, Christchurch, New Zealand
Thromb Haemost 96:535-7. 2006
Fibrinogen Tolaga Bay: a novel gammaAla341Val mutation causing hypofibrinogenaemiaRyan L Davis
Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
Thromb Haemost 98:1136-8. 2007
Deletion of five residues from the coiled coil of fibrinogen (Bbeta Asn167_Glu171del) associated with bleeding and hypodysfibrinogenemiaStephen O Brennan
Molecular Pathology Laboratory, Canterbury Health Laboratories, PO Box 151, Christchurch, New Zealand
Haematologica 94:585-8. 2009..Mechanistically the 15-nucleotide deletion appears to arise from replication advancement during DNA synthesis caused by a flanking pentanucleotide repeat of AATGA...
Novel fibrinogen mutation ?314Thr?Pro (fibrinogen AI duPont) associated with hepatic fibrinogen storage disease and hypofibrinogenaemiaStephen O Brennan
Molecular Pathology Laboratory, Christchurch School of Medicine University of Otago, Christchurch, New Zealand
Liver Int 30:1541-7. 2010..We describe only the fourth mutation to be identified, ?314Thr?Pro (fibrinogen AI duPont), giving rise to hypofibrinogenaemia and hepatic fibrinogen storage disease...
Congenital hypodysfibrinogenaemia (Fibrinogen Des Moines) due to a gamma320Asp deletion at the Ca2+ binding siteStephen O Brennan
Molecular Pathology Laboratory, Christchurch School of Medicine, Christchurch, New Zealand
Thromb Haemost 98:467-9. 2007
