Research Topics
Genomes and Genes | Troels R PetersenSummaryAffiliation: Malaghan Institute of Medical Research Country: New Zealand Publications
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Detail Information
Publications
Characterization of MHC- and TCR-binding residues of the myelin oligodendrocyte glycoprotein 38-51 peptideTroels R Petersen
Malaghan Institute of Medical Research, Wellington South, New Zealand
Eur J Immunol 34:165-73. 2004..Our results could be useful to design peptides with altered agretopes and epitopes of the MOG(38-51) peptide to study their therapeutic potential in the EAE model...
Potent anti-tumor responses to immunization with dendritic cells loaded with tumor tissue and an NKT cell ligandTroels R Petersen
Malaghan Institute of Medical Research, Wellington, New Zealand
Immunol Cell Biol 88:596-604. 2010..Inactivating regulatory T cells and eliciting iNKT cell activation are therefore two useful strategies that can be used in combination to improve anti-tumor immunization with antigen-loaded DCs...
Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccinesTroels R Petersen
Malaghan Institute of Medical Research, Wellington, New Zealand
PLoS ONE 6:e17657. 2011....
Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigensKathryn J Farrand
Malaghan Institute of Medical Research, Wellington, New Zealand
J Immunol 183:7732-42. 2009..These data suggest a critical role for the langerin(+) compartment of the CD8alpha(+) DC population in cross-priming and IL-12 production...
Tumor antigen presentation by dendritic cellsTroels R Petersen
Malaghan Institute of Medical Research, Wellington, New Zealand
Crit Rev Immunol 30:345-86. 2010..In this context, recruiting the activity of cells of the innate immune system to condition host DCs may help elicit more effective T cell-mediated responses...
A chimeric T cell receptor with super-signaling propertiesTroels R Petersen
Malaghan Institute of Medical Research, Wellington, New Zealand
Int Immunol 16:889-94. 2004....
A chimeric TCR-beta chain confers increased susceptibility to EAETroels R Petersen
Malaghan Institute of Medical Research, P O Box 7060, Wellington South, New Zealand
Mol Immunol 44:3473-81. 2007..Investigating the molecular interaction within the TCR complex will help us to identify signalling pathways that can be manipulated to stop the progression of MS...
