Philippe Mondon

Summary

Publications

  1. ncbi Method for generation of human hyperdiversified antibody fragment library
    Philippe Mondon
    Department of Molecular Evolution and Department of Bioinformatics, MilleGen SA, Labège France
    Biotechnol J 2:76-82. 2007
  2. ncbi Human antibody libraries: a race to engineer and explore a larger diversity
    Philippe Mondon
    MilleGen S A, Immeuble BIOSTEP Batiment A, rue Pierre et Marie Curie, BP 38183, 31681 Labege, Cedex, France
    Front Biosci 13:1117-29. 2008
  3. ncbi Mutagen: a random mutagenesis method providing a complementary diversity generated by human error-prone DNA polymerases
    Philippe Mondon
    Antibody Engineering and Molecular Evolution Department, MilleGen SA, Labege, France
    Methods Mol Biol 634:373-86. 2010
  4. ncbi A cytoplasmic protein-protein interaction detection method based on reporter translation
    Laurence Renaut
    MilleGen, Immeuble BIOSTEP, 31681 Labege Cedex, France
    Anal Biochem 384:362-4. 2009
  5. ncbi Cryptococcus neoformans with a mutation in the tetratricopeptide repeat-containing gene, CCN1, causes subcutaneous lesions but fails to cause systemic infection
    Seyung Chung
    Molecular Microbiology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Infect Immun 71:1988-94. 2003
  6. ncbi Combinatorial engineering to enhance thermostability of amylosucrase
    Stéphane Emond
    Universite de Toulouse, INSA, UPS, INP, LISBP, F 31077 Toulouse, France
    Protein Sci 17:967-76. 2008

Collaborators

  • Laurence Renaut
  • Stéphane Emond
  • Seyung Chung
  • Pierre Monsan
  • Gabrielle Potocki-Veronese
  • Hakim Kharrat
  • Isabelle André
  • Kais Jaziri
  • Khalil Bouayadi
  • Magali Remaud-Simeon
  • Yun C Chang
  • Kyung J Kwon-Chung

Detail Information

Publications6

  1. ncbi Method for generation of human hyperdiversified antibody fragment library
    Philippe Mondon
    Department of Molecular Evolution and Department of Bioinformatics, MilleGen SA, Labège France
    Biotechnol J 2:76-82. 2007
    ..8 mutations per 100 amino acids. The hyperdiversified antibody fragment libraries constructed with our process should enable the selection of antibody fragments specific to virtually any target...
  2. ncbi Human antibody libraries: a race to engineer and explore a larger diversity
    Philippe Mondon
    MilleGen S A, Immeuble BIOSTEP Batiment A, rue Pierre et Marie Curie, BP 38183, 31681 Labege, Cedex, France
    Front Biosci 13:1117-29. 2008
    ..Here we review some of these prominent approaches in the field of human recombinant antibody libraries...
  3. ncbi Mutagen: a random mutagenesis method providing a complementary diversity generated by human error-prone DNA polymerases
    Philippe Mondon
    Antibody Engineering and Molecular Evolution Department, MilleGen SA, Labege, France
    Methods Mol Biol 634:373-86. 2010
    ..By taking advantage of the mutation bias of naturally highly error-prone DNA polymerases, MutaGen thus appears as a very useful tool for gene and protein randomization...
  4. ncbi A cytoplasmic protein-protein interaction detection method based on reporter translation
    Laurence Renaut
    MilleGen, Immeuble BIOSTEP, 31681 Labege Cedex, France
    Anal Biochem 384:362-4. 2009
    ..This novel cytoplasmic protein-protein interaction (CPPI) detection system should prove to be useful in the characterization of proteins as well as in partner identification, interaction mapping, and drug discovery applications...
  5. ncbi Cryptococcus neoformans with a mutation in the tetratricopeptide repeat-containing gene, CCN1, causes subcutaneous lesions but fails to cause systemic infection
    Seyung Chung
    Molecular Microbiology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Infect Immun 71:1988-94. 2003
    ..CLF1 complemented the Ts phenotype of B-4551. CCN1, however, failed to rescue the clf1 mutant in S. cerevisiae. These results indicate that the Ccn1p may not be as functionally diverse as Clf1p in yeast...
  6. ncbi Combinatorial engineering to enhance thermostability of amylosucrase
    Stéphane Emond
    Universite de Toulouse, INSA, UPS, INP, LISBP, F 31077 Toulouse, France
    Protein Sci 17:967-76. 2008
    ..At this temperature, amylose synthesis by this variant using high sucrose concentration (600 mM) led to the production of amylose chains twice as long as those obtained by the wild-type enzyme at 30 degrees C...