Erythropoietin and erythropoietin receptor expression in human endometrium throughout the menstrual cycleRei Yokomizo
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, 1 1, Seiryo machi, Aoba ku, Sendai, 980 8574, Japan
Mol Hum Reprod 8:441-6. 2002
..In addition, we also hypothesize that ovarian steroids may stimulate Epo production in human endometrial glandular epithelial cells...
- DNA microarray analysis of gene expression in eutopic endometrium from patients with deep endometriosis using laser capture microdissection
Sachiko Matsuzaki
Department of Gynecology, Hotel Dieu, Polyclinique, Centre Hospitalier Universitaire, Clermont Ferrand, France
Fertil Steril 84:1180-90. 2005
....
- Differential expression of genes in eutopic and ectopic endometrium from patients with ovarian endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, France
Fertil Steril 86:548-53. 2006
....
- Epithelial to mesenchymal transition-like and mesenchymal to epithelial transition-like processes might be involved in the pathogenesis of pelvic endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, CHU Estaing, Chirurgie Gynécologique, 1, place Lucie Aubrac, 63003 Clermont Ferrand, France
Hum Reprod 27:712-21. 2012
..We hypothesized that pelvic endometriosis originates from retrograde menstruation of endometrial tissue and that EMT-like and MET-like processes might be involved in the pathogenesis of pelvic endometriosis...
- Impact of the surgical peritoneal environment on pre-implanted tumors on a molecular level: a syngeneic mouse model
Sachiko Matsuzaki
Université d Auvergne Clermont I, Centre d endoscopy et des Nouvelles Techniques Interventionnelles CENTI, Clermont Ferrand, France
J Surg Res 162:79-87. 2010
..The objective of the present study was to evaluate the impact of the surgical peritoneal environment on pre-implanted tumors on a molecular level...
- Expression of WT1 is down-regulated in eutopic endometrium obtained during the midsecretory phase from patients with endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, France
Fertil Steril 86:554-8. 2006
..To investigate whether WT1 protein expression is altered in eutopic endometrium of endometriosis patients...
- Relationship between delay of surgical diagnosis and severity of disease in patients with symptomatic deep infiltrating endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, Polyclinique de l Hotel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Clermont Ferrand, France
Fertil Steril 86:1314-6; discussion 1317. 2006
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- Both GnRH agonist and continuous oral progestin treatments reduce the expression of the tyrosine kinase receptor B and mu-opioid receptor in deep infiltrating endometriosis
S Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, France
Hum Reprod 22:124-8. 2007
..In this study, we compared mRNA expression levels of TrKB, MOR and 5HTT in DIE among patients pre-operatively treated with GnRH agonist, progestin or without pre-operative medical treatments...
- Effects of a protein kinase C inhibitor on the initial development of ectopic implants in a syngeneic mouse model of endometriosis
Sachiko Matsuzaki
Université d Auvergne Clermont I, Centre d Endoscopie et des Nouvelles Techniques Interventionnelles, Clermont Ferrand, France
Fertil Steril 89:206-11. 2008
..To evaluate the effect of protein kinase C inhibition on surgically induced endometriosis in mice...
- Effects of supplemental perioperative oxygen on post-operative abdominal wound adhesions in a mouse laparotomy model with controlled respiratory support
Sachiko Matsuzaki
Université d Auvergne Clermont I, Faculte de Medecine, Centre d Endoscopie et des Nouvelles Techniques Interventionnelles CENTI, Clermont Ferrand, France
Hum Reprod 22:2702-6. 2007
..The objective of this study was to investigate whether supplemental perioperative oxygen could reduce post-operative adhesion formation through increasing the peritoneal tissue oxygen tension (PitO(2)) in a mouse model...
- Excision of the posterior vaginal fornix is necessary to ensure complete resection of rectovaginal endometriotic nodules of more than 2 cm in size
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétriqueet Médecine de la Reproduction, Clermont Ferrand, France
Fertil Steril 91:1314-5. 2009
..1%), and <5,000 microm in 60 patients (98.4%). Our findings provided histologic evidence that excision of the posterior vaginal fornix was necessary to completely remove large rectovaginal endometriotic nodules...
- Molecular mechanisms underlying postoperative peritoneal tumor dissemination may differ between a laparotomy and carbon dioxide pneumoperitoneum: a syngeneic mouse model with controlled respiratory support
Sachiko Matsuzaki
Université d Auvergne Clermont I, Centre d Endoscopie et des Nouvelles Techniques Interventionnelles, Clermont Ferrand, France
Surg Endosc 23:705-14. 2009
..The mechanisms promoting postoperative peritoneal tumor dissemination are unclear. This study aimed to investigate postoperative tumor dissemination over time on both tissue and molecular levels...
- Analysis of risk factors for the removal of normal ovarian tissue during laparoscopic cystectomy for ovarian endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Boulevard Leon Malfreyt, 63058 Clermont Ferrand, France
Hum Reprod 24:1402-6. 2009
..The aim of this study was to identify risk factors for the removal of normal ovarian tissue during laparoscopic cystectomy for endometriosis...
- HOXA-10 expression in the mid-secretory endometrium of infertile patients with either endometriosis, uterine fibromas or unexplained infertility
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Boulevard Leon Malfreyt, 63058 Clermont Ferrand, France
Hum Reprod 24:3180-7. 2009
..The aim of this study was to investigate HOXA-10 expression in endometrium from infertile patients with different forms of endometriosis; with uterine fibromas, or with unexplained infertility and from normal fertile women...
- Oxidative stress status in normal ovarian cortex surrounding ovarian endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, 63058, Clermont Ferrand, France
Fertil Steril 93:2431-2. 2010
..These findings suggest that the normal ovarian cortex surrounding endometriotic tissues is more severely affected by oxidative stress than ovarian cortex adjacent to other benign ovarian cysts...
- Analysis of matrix metalloproteinase-7 expression in eutopic and ectopic endometrium samples from patients with different forms of endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Boulevard Leon Malfreyt, 63058 Clermont Ferrand, France
Hum Reprod 25:742-50. 2010
..The objective of the present study was to expand our understanding of the role of matrix metalloproteinase-7 (MMP-7) in the pathophysiology of endometriosis...
- Carbon dioxide pneumoperitoneum, intraperitoneal pressure, and peritoneal tissue hypoxia: a mouse study with controlled respiratory support
Sachiko Matsuzaki
CHU Clermont Ferrand, Polyclinique de l Hotel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Boulevard Leon Malfreyt, 63058, Clermont Ferrand, France
Surg Endosc 24:2871-80. 2010
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- Impact of intraperitoneal pressure and duration of surgery on levels of tissue plasminogen activator and plasminogen activator inhibitor-1 mRNA in peritoneal tissues during laparoscopic surgery
Sachiko Matsuzaki
Chirurgie Gynécologique, CHU Clermont Ferrand, Clermont Ferrand, France
Hum Reprod 26:1073-81. 2011
..Our objective was to evaluate the impact of intraperitoneal pressure (IPP) and duration of a CO(2) pneumoperitoneum on the peritoneal fibrinolytic system during laparoscopic surgery...
- DNA microarray analysis in endometriosis for development of more effective targeted therapies
Sachiko Matsuzaki
centre hospitalier universitaire de Clermont Ferrand, Chirurgie Gynécologique, Clermont Ferrand, France
Front Biosci (Elite Ed) 3:1139-53. 2011
..The present review discusses the results of a decade of DNA microarray technology experience, with emphasis on the pathophysiology of endometriosis in the context of clinical studies...
- Analysis of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression in deep endometriosis and eutopic endometrium using laser capture microdissection
Sachiko Matsuzaki
Department of Gynecology, Polyclinique de l Hotel Dieu, CHU, Clermont Ferrand, France
Fertil Steril 85:308-13. 2006
..To investigate mRNA expression of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 (17betaHSD2) in epithelial and stromal cells from eutopic and ectopic endometrium of patients with deep endometriosis...
- Expression of erythropoietin and erythropoietin receptor in peritoneal endometriosis
Sachiko Matsuzaki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, 1 1, Seiryo machi, Aoba ku, Sendai, 980 8574, Japan
Hum Reprod 18:152-6. 2003
..Therefore, we hypothesized that Epo may play a role in the pathogenesis of endometriosis, particularly during the early stages of the disease...
- DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection
S Matsuzaki
Department of Gynecology, Polyclinique de l Hotel Dieu, CHU, Clermont Ferrand, France
Mol Hum Reprod 10:719-28. 2004
..One of the candidate genes, MOR, may be involved in a defective immune system in endometriosis. This study has provided new insights into endometriosis pathophysiology...
- Cyclooxygenase-2 expression in deep endometriosis and matched eutopic endometrium
Sachiko Matsuzaki
Department of Gynecology, Hotel Dieu, Polyclinique, CHU, Clermont Ferrand, France
Fertil Steril 82:1309-15. 2004
..To identify any relationship between cyclooxygenase-2 expression and the intensity of severe, endometriosis-related dysmenorrhea...
- Cyclooxygenase-2 selective inhibitor prevents implantation of eutopic endometrium to ectopic sites in rats
Sachiko Matsuzaki
Department of Gynecology, Polyclinique de l Hotel Dieu, CHU Clermont Ferrand, Clermont Ferrand, France
Fertil Steril 82:1609-15. 2004
..To evaluate Cox-2 inhibition on surgically induced endometriosis in rats...
- Immunohistochemical analysis of the role of angiogenic status in the vasculature of peritoneal endometriosis
S Matsuzaki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Fertil Steril 76:712-6. 2001
..To investigate the angiogenic status of the vasculature in peritoneal endometriosis based on macroscopic appearance...
- Impaired down-regulation of E-cadherin and beta-catenin protein expression in endometrial epithelial cells in the mid-secretory endometrium of infertile patients with endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Clermont Ferrand, Boulevard Leon Malfreyt, 63058 Clermont Ferrand, France
J Clin Endocrinol Metab 95:3437-45. 2010
..It remains unclear whether expression of these molecules might be altered in the endometrium of infertile patients with endometriosis...
- Impact of surgical peritoneal environment on postoperative tumor growth and dissemination in a preimplanted tumor model
Anne Sophie Azuar
Centre d Endoscopie et des Nouvelles Techniques Interventionnelles, Université d Auvergne Clermont I, Clermont Ferrand, France
Surg Endosc 23:1733-9. 2009
..The objective of the present study was to evaluate the impact of surgical peritoneal environment on postoperative tumor growth and dissemination over time when tumors were present before surgery...
- Postoperative peritoneal dissemination of ovarian cancer cells is not promoted by carbon-dioxide pneumoperitoneum at low intraperitoneal pressure in a syngenic mouse laparoscopic model with controlled respiratory support: a pilot study
Nicolas Bourdel
Université d Auvergne Clermont I, Centre d Endoscopie et des Nouvelles Techniques Interventionnelles, Clermont Ferrand, France
J Minim Invasive Gynecol 15:321-6. 2008
..To investigate postoperative peritoneal dissemination of ovarian cancer cells in a syngenic mouse model with and without controlled respiratory support (CRS)...
- Peritoneal tissue-oxygen tension during a carbon dioxide pneumoperitoneum in a mouse laparoscopic model with controlled respiratory support
Nicolas Bourdel
Université d Auvergne Clermont I, Centre d Endoscopie et des Nouvelles Techniques Interventionnelles CENIT, Faculte de Medecine, Clermont Ferrand, France
Hum Reprod 22:1149-55. 2007
....
- [Peritoneum and laparoscopic environment]
Michel Canis
Service de gynécologie obstétrique et médecine de la reproduction, CHU, Polyclinique Hôtel Dieu bd Léon Malfreyt, 63058 Clermont Ferrand Cedex 1, France
Bull Cancer 94:1043-51. 2007
..This approach may even appear essential to all the surgeons who are using endoscopy in a retroperitoneal space such as urologists or endocrine surgeons...
- Comparison between standard and reverse laparoscopic techniques for rectovaginal endometriosis
William Kondo
Department of Gynecologic Surgery, CHU Estaing, Clermont Ferrand, France
Surg Endosc 25:2711-7. 2011
..This study was designed to compare the surgical outcomes of standard and reverse laparoscopic techniques for the treatment of rectovaginal endometriosis...
- Prediction of pregnancy in infertile women with endometriosis
Takashi Murakami
Department of Obstetrics and Gynecology, School of Medicine, Tohoku University, Sendai, Japan
Gynecol Obstet Invest 53:26-32. 2002
..Only TNF-alpha was selected with a forward stepwise analysis after forcing age and infertile duration. In the logistic regression model, the serum TNF-alpha level had a significant and negative impact on the likelihood of pregnancy...
- Telomerase activity in normal ovaries and premature ovarian failure
C Kinugawa
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Tohoku J Exp Med 190:231-8. 2000
..Based on these results, we speculated that the decline of telomerase activity in the ovary is related to primordial follicle depletion with age and telomerase activity can be used as a marker of the ovarian functional age...
- Use of laser capture microdissection in studying hormone-dependent diseases: endometriosis
Sachiko Matsuzaki
CHU Clermont Ferrand, polyclinique Hôtel Dieu, Gynécologie Obstétrique et Médecine de la Reproduction, Clermont Ferrand Cedex, France
Methods Mol Biol 590:295-306. 2009
....
- Quantitative analysis of estrogen receptor alpha and beta messenger ribonucleic acid levels in normal endometrium and ovarian endometriotic cysts using a real-time reverse transcription-polymerase chain reaction assay
S Matsuzaki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Fertil Steril 74:753-9. 2000
..To quantify messenger RNA (mRNA) levels of the two estrogen receptor isoforms, estrogen receptor-alpha (ER-alpha) and estrogen receptor-beta (ER-beta) in the eutopic endometrium and ovarian endometriotic cysts...
- Expression of estrogen receptor alpha and beta in peritoneal and ovarian endometriosis
S Matsuzaki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Fertil Steril 75:1198-205. 2001
..To quantify and compare messenger RNA (mRNA) levels of ER-alpha and ER-beta among ovarian endometriotic cysts and red and black peritoneal endometriotic lesions...
- Expression of the cyclin-dependent kinase inhibitor p27Kip1 in eutopic endometrium and peritoneal endometriosis
S Matsuzaki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Fertil Steril 75:956-60. 2001
..This study was undertaken to evaluate the immunohistochemical expression of the cell cycle inhibitor p27Kip1 and proliferation marker Ki67 in peritoneal endometriosis and eutopic endometrium...
- The macrophage stimulating protein/RON system: a potential novel target for prevention and treatment of endometriosis
S Matsuzaki
Department of Gynecology, Polyclinique de l Hotel Dieu, CHU, Clermont Ferrand, France
Mol Hum Reprod 11:345-9. 2005
..The present findings suggest that the MSP/RON system may be involved in the pathophysiology of endometriosis...
- Erythropoietin concentrations are elevated in the peritoneal fluid of women with endometriosis
S Matsuzaki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Hum Reprod 16:945-8. 2001
..03), III (n = 13, 8.4 +/- 1.0 mIU/ml, P < 0.01), IV disease (n = 7, 7.5 +/- 1.0 mIU/ml, P < 0.01). These data suggest that Epo may play a role in the pathogenesis of endometriosis particularly in the initiation of the disease...
- X-chromosome inactivation in the human trophoblast of early pregnancy
S Uehara
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
J Hum Genet 45:119-26. 2000
..It is probable that transcription of the X inactivation center (XIC) begins earlier in mice than in humans...
- Expression of EBAG9/RCAS1 is associated with advanced disease in human epithelial ovarian cancer
J I Akahira
Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
Br J Cancer 90:2197-202. 2004
..In conclusion, the wide distribution of EBAG9 and its relation to advanced disease suggest that this protein may play important roles in epithelial ovarian cancer...
- Is the dose to inhibit the COX-2 enzyme in nude mice also adequate in 'human' endometrial tissues?
Sachiko Matsuzaki
Hum Reprod 20:2665; author reply 2665-6. 2005
