Research Topics
| Abdul Rahman OmarSummaryAffiliation: Universiti Putra Malaysia Country: Malaysia Publications
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Detail Information
Publications
Cellular transcripts regulated during infections with Highly Pathogenic H5N1 Avian Influenza virus in 3 host systemsVinod Rmt Balasubramaniam
Infectious Disease Laboratory MR3, School of Medicine and Health Sciences, Monash University, Sunway Campus, Kuala Lumpur, Malaysia
Virol J 8:196. 2011..Understanding the genes and proteins involved in host cellular responses are therefore, critical for the elucidation of the mechanisms of infection...
Detection and characterization of chicken anemia virus from commercial broiler breeder chickensZerihun Hailemariam
Faculty of Veterinary Medicine, Haramaya University, P O Box 271, Haramaya, Ethiopia
Virol J 5:128. 2008..Hence, the present study was aimed to detect CAV from commercial broiler breeder farms and characterize CAV positive samples based on sequence and phylogenetic analysis of partial VP1 gene...
Molecular characterization of partial fusion gene and C-terminus extension length of haemagglutinin-neuraminidase gene of recently isolated Newcastle disease virus isolates in MalaysiaAyalew Berhanu
Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Darul Ehsan, Malaysia
Virol J 7:183. 2010....
Descriptive distribution and phylogenetic analysis of feline infectious peritonitis virus isolates of MalaysiaSaeed Sharif
Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Acta Vet Scand 52:1. 2010..The overall branching pattern of phylogenetic tree showed two distinct clusters, where all Malaysian isolates fall into one main genetic cluster. These findings provided the first genetic information of FCoV in Malaysia...
Efficacy of VP2 protein expressed in E. coli for protection against highly virulent infectious bursal disease virusAbdul Rahman Omar
Institute of Bioscience, University Putra Malaysia, 43400 UPM Serdang, Selangor Darul Ehsan, Malaysia
J Vet Sci 7:241-7. 2006..Thus, antibodies raised against IBDV VP2 protein expressed in E. coli and denatured IBDV proteins induced some degree of protection against mortality but not against bursal damage following challenge with hvIBDV...
Development of avian influenza virus H5 DNA vaccine and MDP-1 gene of Mycobacterium bovis as genetic adjuvantBabak Jalilian
Institute of Bioscience, University Putra Malaysia, Serdang 43400, Selangor, Malaysia
Genet Vaccines Ther 8:4. 2010..Vaccines are frequently formulated with adjuvants to improve their release, delivery and presentation to the host immune system...
Development of a DNA vaccine against chicken anemia virus by using a bicistronic vector expressing VP1 and VP2 proteins of CAVHassan Moeini
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
Comp Immunol Microbiol Infect Dis 34:227-36. 2011..These results suggest that the recombinant DNA plasmid co-expressing VP1 and VP2 can be used as a potential DNA vaccine against CAV...
Improving the potency of DNA vaccine against chicken anemia virus (CAV) by fusing VP1 protein of CAV to Marek's Disease Virus (MDV) type-1 VP22 proteinHassan Moeini
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
Virol J 8:119. 2011..The ability to facilitate the spreading of the linked proteins was used to improve the potency of the constructed DNA vaccines against chicken anemia virus (CAV)...
Development of SYBR green I based one-step real-time RT-PCR assay for the detection and differentiation of very virulent and classical strains of infectious bursal disease virusLih Ling Kong
Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
J Virol Methods 161:271-9. 2009..The assay showed high sensitivity since bursal samples which were negative for IBDV were confirmed by virus isolation and PCR amplification. Hence, the new assay offers an attractive method for rapid detection of strains of IBDV...
Identification and characterisation of a novel anti-viral peptide against avian influenza virus H9N2Mohamed Rajik
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, UPM Serdang, Selangor, 43400, Malaysia
Virol J 6:74. 2009..In order to identify a peptide-based virus inhibitor against any of these surface proteins, a disulfide constrained heptapeptide phage display library was biopanned against purified AIV sub-type H9N2 virus particles...
DNA vaccine encoding avian influenza virus H5 and Esat-6 of Mycobacterium tuberculosis improved antibody responses against AIV in chickensSara Oveissi
Institute of Bioscience, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Comp Immunol Microbiol Infect Dis 33:491-503. 2010..1/H5/Esat-6 was higher compared to the chickens immunized with pcDNA3.1/H5 (p<0.05). The results suggested that Esat-6 gene of M. tuberculosis is a potential genetic adjuvant for the development of effective H5 DNA vaccine in chickens...
Detection and differentiation of velogenic and lentogenic Newcastle disease viruses using SYBR Green I real-time PCR with nucleocapsid gene-specific primersSheau Wei Tan
Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
J Virol Methods 160:149-56. 2009..The assay offers an attractive alternative method for the diagnosis of NDV...
Lactobacillus acidophilus as a live vehicle for oral immunization against chicken anemia virusHassan Moeini
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malysia, 43400, Serdang, Selangor, Malaysia
Appl Microbiol Biotechnol 90:77-88. 2011..The vaccinated groups also showed increased levels of Th1 cytokines interleukin (IL)-2, IL-12, and IFN-?. These observations suggest that L. acidophilus can be used in the delivery of vaccines to chickens...
Attenuation of influenza virus infectivity with herbal-marine compound (HESA-A): an in vitro study in MDCK cellsParvaneh Mehrbod
Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
Virol J 9:44. 2012..Previous studies have reported that the therapeutic properties of HESA-A are able to treat psoriasis vulgaris and cancers. However, no antiviral properties have been reported...
Safety and clinical usage of newcastle disease virus in cancer therapyHan Yuen Lam
Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
J Biomed Biotechnol 2011:718710. 2011..Safety of NDV strains applied for cancer immunotherapy is also discussed in this paper...
Immunomodulatory Effect of Rhaphidophora korthalsii on Natural Killer Cell CytotoxicitySwee Keong Yeap
Institute of Bioscience, Putra University, Malaysia, Serdang, 43400 Selangor, Malaysia
Evid Based Complement Alternat Med 2012:786487. 2012....
Comparison of different methods for the isolation of mesenchymal stem cells from human umbilical cord Wharton's jellyParvin Salehinejad
Institute of Bioscience, University Putra Malaysia, Kuala Lumpur, Malaysia
In Vitro Cell Dev Biol Anim 48:75-83. 2012..These cells expressed a higher rate of pluripotent cell markers such as C-kit and Oct-4, while the explant method of cell isolation resulted in a higher cell proliferation rate and activity compared to the other methods...
A novel peptide inhibits the influenza virus replication by preventing the viral attachment to the host cellsMohamed Rajik
Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia
Int J Biol Sci 5:543-8. 2009..This novel peptide may have the potential to be developed as a therapeutic agent for the treatment and control of avian influenza virus H9N2 infections...
Development of a multiplex real-time PCR assay using SYBR Green 1 chemistry for simultaneous detection and subtyping of H9N2 influenza virus type AWee Theng Ong
Institute of Biosciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
J Virol Methods 144:57-64. 2007..In addition, the RRT-PCR assay was 100% sensitive as well as 92% specific according to the standard virus isolation method in detecting experimentally infected specific-pathogen-free (SPF) chickens...
Engineering an L-cell line that expresses insulin under the control of the glucagon-like peptide-1 promoter for diabetes treatmentMina Rasouli
Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia
BMC Biotechnol 11:99. 2011..abstract:..
Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liverFatemeh Abedini
Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia, Selangor Darul Ehsan, Malaysia
Cancer Manag Res 3:301-9. 2011..More research will be needed to determine the effect of CXCR4 silencing on serum LDH levels, which may be a useful marker for predicting liver metastasis in colorectal cancer...
Ultrastructure of Felis catus whole fetus (Fcwf-4) cell culture following infection with feline coronavirusAmer Alazawy
Department of Veterinary Pathology and Microbiology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
J Electron Microsc (Tokyo) 60:275-82. 2011..Thereafter, intracellular virus particles were observed to be present in vacuoles or present freely in the cytoplasm...
Selective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cellsMothanna Al-Qubaisi
Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia UPM, 43400 Serdang, Selangor, Malaysia
Molecules 16:2944-59. 2011..Goniothalamin selectively killed liver cancer cell through suppression of proliferation and induction of apoptosis. These results suggest that goniothalamin shows potential cytotoxicity against hepatoblastoma HepG2 cells...
Base usage and dinucleotide frequency of infectious bursal disease virusDo Yew Tan
Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM, Serdang, Selangor, Malaysia
Virus Genes 28:41-53. 2004..In summary, the study of base usage and dinucleotide frequency had unravelled many overlooked genomic properties of the virus...
