A randomized clinical trial of community-based directly observed therapy as an adherence intervention for HAART among substance usersGrace E Macalino
Arthur Ashe Institute for Urban Health, Brown University, Providence, RI, USA
AIDS 21:1473-7. 2007
..Adherence interventions for HAART can impact challenging populations, such as active substance users. Community-based modified directly observed therapy (MDOT) is a promising approach that needs to be critically evaluated...
- Modified directly observed therapy for the treatment of HIV-seropositive substance users: lessons learned from a pilot study
Grace E Macalino
Department of Community Health, Providence, RI 02913, USA
Clin Infect Dis 38:S393-7. 2004
..Tapering the intensity of visits with maximum flexibility was necessary to enhance the acceptability of the program to participants...
- Directly observed antiretroviral therapy to reduce genital tract and plasma HIV-1 RNA in women with poor adherence
Joseph I Harwell
Brown University, Providence, RI, USA
AIDS 17:1990-3. 2003
..6 log10 copies/ml) CVL HIV-1-RNA levels by 3 months and undetectable plasma HIV-1-RNA levels by 6 months. The mean CD4 cell increase was 76 cells/mm3. DOT appears effective and may reduce infectiousness in this high-risk population...
- The use of community-based modified directly observed therapy for the treatment of HIV-infected persons
Jennifer A Mitty
The Brown University Medical School and the Miriam Hospital, Providence, RI 02906, USA
J Acquir Immune Defic Syndr 39:545-50. 2005
..These results support that MDOT should be included in the spectrum of options available to enhance adherence to HAART among patients who are unsuccessful with self-administration of their medications...
- Prevalence and incidence of HIV, hepatitis B virus, and hepatitis C virus infections among males in Rhode Island prisons
Grace E Macalino
Brown University Medical School, Providence, RI 02912, USA
Am J Public Health 94:1218-23. 2004
..We evaluated prevalence and intraprison incidence of HIV, hepatitis B virus, and hepatitis C virus infections among male prison inmates...
- Drug use patterns over time among HIV-seropositive and HIV-seronegative women: the HER study experience
Grace E Macalino
Brown University Medical School, Providence, Rhode Island 02912, USA
J Acquir Immune Defic Syndr 33:500-5. 2003
..Alternatively, increased drug use may occur due to depression associated with being HIV infected, leading to despair, hopelessness, and a lack of motivation to become drug free...
- A syringe prescription program to prevent infectious disease and improve health of injection drug users
Josiah D Rich
School of Medicine at Brown University, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA
J Urban Health 81:122-34. 2004
..The syringe prescription program in Providence represents a promising and innovative approach to disease prevention and treatment for IDUs...
- Risk behaviors by audio computer-assisted self-interviews among HIV-seropositive and HIV-seronegative injection drug users
Grace E Macalino
Department of Community Health, Brown University, School of Medicine, Providence, RI 02912, USA
AIDS Educ Prev 14:367-78. 2002
..These findings support the validity of ACASI as an important mode of data collection in reducing socially desirable responding, especially among HIV-seropositive subjects...
