The acute phase response stimulates the expression of angiopoietin like protein 4Biao Lu
Metabolism Section, Department of Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA 94121, USA
Biochem Biophys Res Commun 391:1737-41. 2010
..These studies demonstrate that ANGPTL4 is a positive acute phase protein and the increase in ANGPTL4 could contribute to the hypertriglyceridemia that characteristically occurs during the acute phase response by inhibiting LPL activity...
- Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response
Biao Lu
Metabolism Section, Department of Veterans Affairs Medical Center, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
Biochim Biophys Acta 1771:1177-85. 2007
..These data provide evidence that PLSCR1 is a positive intracellular acute phase protein with a tissue-specific mechanism for up-regulation...
- Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response
Biao Lu
Metabolism Section, Department of Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA 94121, USA
J Lipid Res 47:2179-90. 2006
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- LPS and proinflammatory cytokines decrease lipin-1 in mouse adipose tissue and 3T3-L1 adipocytes
Biao Lu
Department of Veterans Affairs Medical Center, University of California, San Francisco, CA, USA
Am J Physiol Endocrinol Metab 295:E1502-9. 2008
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- PPAR? activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation
Yan J Jiang
Department of Veterans Affairs Medical Center, Metabolism Section, Veterans Affairs Medical Center, San Francisco, California 94121, USA
J Invest Dermatol 130:511-9. 2010
..These studies show that PPARdelta has a role in SC formation and permeability barrier development...
- Regulation of ABCG1 expression in human keratinocytes and murine epidermis
Yan J Jiang
Metabolism Section, Veterans Affairs Medical Center, Northern California Institute for Research and Education, University of California at San Francisco, San Francisco, CA 94121, USA
J Lipid Res 51:3185-95. 2010
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- PPAR and LXR activators regulate ABCA12 expression in human keratinocytes
Yan J Jiang
Metabolism Section, Department of Veterans Affairs Medical Center, Northern California Institute for Research and Education, University of California at San Francisco, San Francisco, California 94121, USA
J Invest Dermatol 128:104-9. 2008
..Together, our data demonstrate that PPAR and LXR activators increase ABCA12 expression, providing an additional mechanism by which PPAR and LXR activators promote epidermal permeability barrier homeostasis...
- Ceramide stimulates ABCA12 expression via peroxisome proliferator-activated receptor {delta} in human keratinocytes
Yan J Jiang
Metabolism Section, Veterans Affairs Medical Center, Northern California Institute for Research and Education, University of California, San Francisco, California 94121, USA
J Biol Chem 284:18942-52. 2009
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- Cardiolipin synthase-1 mRNA expression does not correlate with endogenous cardiolipin synthase enzyme activity in vitro and in vivo in mammalian lipopolysaccharide models of inflammation
Biao Lu
Department of Medicine, University of California, San Francisco, CA 94121, USA
Inflammation 34:247-54. 2011
..The results clearly indicate that CLS mRNA levels cannot be correlated with CLS enzyme activity nor CL content in the LPS model of inflammation...
- IL-6 stimulates but is not essential for stratum corneum formation and permeability barrier development during gestation
Yan J Jiang
Metabolism Section, NCIRE, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
Exp Dermatol 19:e31-6. 2010
..These low IL-6 levels may account, at least in part, for the absence of epidermal abnormalities in IL-6 KO mice. In conclusion, exogenous IL-6 accelerates epidermal ontogenesis, but it is not essential for normal epidermal maturation...
- Regulation of ABCA1 expression in human keratinocytes and murine epidermis
Yan J Jiang
Metabolism Section, Veterans Affairs Medical Center, Northern California Institute for Research and Education, University of California at San Francisco, San Francisco, CA 94121, USA
J Lipid Res 47:2248-58. 2006
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- Cloning and characterization of a cDNA encoding human cardiolipin synthase (hCLS1)
Biao Lu
Department of Dermatology, University of California, San Francisco, CA 94121, USA
J Lipid Res 47:1140-5. 2006
..Furthermore, the hCLS1 gene was highly expressed in tissues such as heart, skeletal muscle, and liver, which have been shown to have high CLS activities. These results demonstrate that hCLS1 encodes an enzyme that synthesizes CL...
- Regulation of cytosolic phospholipase A2, cyclooxygenase-1 and -2 expression by PMA, TNFalpha, LPS and M-CSF in human monocytes and macrophages
Yan J Jiang
Department of Pathology, Center for Research and Treatment of Atherosclerosis, Faculty of Medicine, University of Manitoba, Winnipeg, Canada
Mol Cell Biochem 246:31-8. 2003
..In addition, PMA stimulates PGE2 production via up-regulation of COX-1, and likely COX-2, expression in U937 cells whereas LPS stimulates PGE2 production via induction of COX-2 expression in macrophages...
- [Impacts of osteoclast-like cells cultured on bone wafer and their sub-cellular structures on osteoblast]
Mei Zhu
Department of Endocrinology, General Hospital of Tianjin Medical University, Tianjin 300052, China
Zhonghua Yi Xue Za Zhi 85:738-42. 2005
..8% +/- 4.5%, all P < 0.05). CONCLUSION: The sub-cellular elements of OLC and the supernatant of OLC culture media free of OLC promote the functions of OB, especially the OLCs cultured on bone wafer...
- Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart
Biao Lu
Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0T6
Biochem J 385:469-77. 2005
..Finally, mRNA expression of cardiac mAGPAT3 appeared to be regulated by PPARalpha activation. We conclude that cardiac mAGPAT activity may be regulated by both the composition of mAGPAT isoforms and the levels of each isoform...
- Stimulation of cardiac cardiolipin biosynthesis by PPARalpha activation
Yan J Jiang
Center for Research and Treatment of Atherosclerosis and Department of Biochemistry and Medical Genetics, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
J Lipid Res 45:244-52. 2004
..This study is the first to demonstrate that CL de novo biosynthesis is regulated by PPARalpha activation...
- [Expression of Fas, FasL, and NF-kappa B in the process of osteoclast-like cell apoptosis effected by sodium fluoride]
Yuan-Ming Sun
Department of Radiobiology, Institute of Radiation Medicine, CAMS, PUMC, Tianjin 300192, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 24:491-4. 2002
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- Cyclooxygenase expression is elevated in retinoic acid-differentiated U937 cells
Yan J Jiang
Centre for Research and Treatment of Atherosclerosis, Faculty of Medicine, University of Manitoba, 770 Bannatyne Avenue, Winnipeg, Manitoba, Canada R3E 0W3
Biochim Biophys Acta 1633:51-60. 2003
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- Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells
Quyen Van
Department of Pharmacology and Therapeutics, University of Manitoba, Winnipeg, Manitoba, Canada, R3E 0T6
Biochem J 401:103-9. 2007
..The results identify PLS3 as a novel regulator of CL de novo biosynthesis and its resynthesis...
