Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosisYing Liu
Molecular Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA
Mol Cancer 7:61. 2008
..Here, we tested whether stalling of DNA replication, a common event in cancer cells and the underlying mechanism of various chemotherapeutic agents, can trigger increased soluble H2AX...
- Imatinib mesylate induces quiescence in gastrointestinal stromal tumor cells through the CDH1-SKP2-p27Kip1 signaling axis
Ying Liu
Molecular Virology Program, University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, Pennsylvania15213, USA
Cancer Res 68:9015-23. 2008
..These results encourage further studies to explore compounds that modulate this pathway as antitumor agents in GISTs...
- Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylate
Ying Liu
Molecular Virology Program, University of Pittsburgh Cancer Institute, Pennsylvania 15213, USA
Cancer Res 67:2685-92. 2007
..Our results underscore the importance of H2AX as a human tumor suppressor protein, provide mechanistic insights into imatinib-induced tumor cell apoptosis and establish H2AX as a novel target in cancer therapy...
- Beta2-adrenergic receptor gene polymorphism in Chinese Northern asthmatics
Jin Ming Gao
Department of Respiratory Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730
Chin Med Sci J 19:164-9. 2004
..To investigate whether the polymorphisms of beta2-adrenergic receptor (beta2-AR) at position 16, 27, 164 are associated with asthma in Northern Chinese subjects...
- A transcript profiling approach reveals the zinc finger transcription factor ZNF191 is a pleiotropic factor
Jianzhong Li
Department of Biochemical Pharmacy, Second Military Medical University, Shanghai, PR China
BMC Genomics 10:241. 2009
..In addition, ZNF191 displays a suppressive effect on the transcription; however, little downstream targets have identified...
- The study of electrochemically active microbial biofilms on different carbon-based anode materials in microbial fuel cells
Ying Liu
Institute of Biochemistry, University of Greifswald, Felix Hausdorff Strasse 4, 17487 Greifswald, Germany
Biosens Bioelectron 25:2167-71. 2010
..In addition, the real surface area values measured by BET surface area technique cannot provide a reasonable explanation for suitability of an electrode material for the formation of electrochemically active biofilm...
- Genetic variation and association analyses of the nuclear respiratory factor 1 (nRF1) gene in Chinese patients with type 2 diabetes
Yang Liu
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
Diabetes 57:777-82. 2008
..This study aimed at evaluating associations between NRF1 genetic polymorphisms and development of type 2 diabetes...
- Nicotine combined with okadaic acid or taxol adversely affects bovine oocyte maturation and subsequent embryo development
Guang Peng Li
Key Laboratory of National Education Ministry for Mammalian Reproductive Biology and Biotechnology, Inner Mongolia University, Hohhot, People s Republic of China
Fertil Steril 92:798-805. 2009
..To investigate the effects of nicotine in combination with okadaic acid (OA) or taxol on bovine oocyte maturation and subsequent embryonic development...
- [A1166C polymorphism of the angiotensin II type 1 receptor gene and essential hypertension in Han, Tibetan and Yi populations]
Ying Liu
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100005 PR China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:220-4. 2003
..To clarify whether A1166C polymorphism of the angiotensin II type 1 receptor (AT(1)R) gene is associated with susceptibility to essential hypertension in Han, Tibetan and Yi populations in China...
- Colcemid-treatment of heifer oocytes enhances nuclear transfer embryonic development, establishment of pregnancy and development to term
Guang Peng Li
Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, Utah 84321, USA
Mol Reprod Dev 76:620-8. 2009
..Five of 40 recipients (12.5%) which received embryos from colcemid-treated oocytes delivered healthy calves, significantly higher than those recipients (3.3%) that received embryos derived from nontreated oocytes...
- [Identification of protein antigen for antibody DBD02 by biopanning of T7 phage display library]
Xiang He
Department of Immunology, Beijing Institute of Radiation Medicine, Beijing 100850, China
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 23:847-9. 2007
..To identify the specificity of mAb DBD02, we developed and optimized a new method by biopanning of T7 Select human liver cDNA phage display library...
- Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines
Ying Liu
Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA
BMC Dev Biol 6:20. 2006
....
- The transcriptional repression of platelet-derived growth factor receptor-beta by the zinc finger transcription factor ZNF24
Jianzhong Li
Department of Biochemical Pharmacy, Second Military Medical University, Shanghai, China
Biochem Biophys Res Commun 397:318-22. 2010
..Overexpression of ZNF24 resulted in a significant decrease in PDGFR-beta promoter activity. These data suggest that ZNF24 is involved in negative regulation of PDGFR-beta and may represent a novel repressor of PDGFR-beta transcription...
- [Analysis on competition and coexistence patterns of Aneurolepidium chinense and its main companion species]
Lei Ba
National Laboratory of Grassland, Ecological Engineering, Key Laboratory for Vegetation Ecology of Education Ministry, Northeast Normal University, Changchun 130024
Ying Yong Sheng Tai Xue Bao 13:50-4. 2002
..A. chinense and Kalimeris interifolia coexisted through competition. Hierochloe glabra and Puccinellia tenuiflora competed with A. chinense through clonal growth. Calamagrostis epigeios was suppressed by A. chinense...
- p21(Waf1/Cip1) deficiency stimulates centriole overduplication
Anette Duensing
Department of Pathology, Molecular Virology Program, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Cell Cycle 5:2899-902. 2006
....
- A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress
Anette Duensing
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Cell Biochem 99:759-69. 2006
..These findings imply that the mitotic spindle checkpoint may act in concert with DNA damage and cell-cycle checkpoints as an early anti-tumor barrier and provide a possible explanation for its frequent relaxation in human cancer...
- Evidence for neural accommodation to a writing system following learning
Ying Liu
Learning Research and Development Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Hum Brain Mapp 28:1223-34. 2007
..The results are consistent with the system accommodation hypothesis: The brain's reading network accommodates to features of an acquired writing system...
- The time course of brain activity in reading English and Chinese: an ERP study of Chinese bilinguals
Ying Liu
Learning Research and Development Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Hum Brain Mapp 18:167-75. 2003
..A post 450-msec visual verification was found to be general for both writing systems...
- Association of -238G/A polymorphism of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection in Chinese Han population
Liang ping Lu
Department of Epidemiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences School of Basic Medicine, Peking Union Medical College, 5 Dongdan 3 Tiao, Beijing 100005, China
World J Gastroenterol 10:1810-4. 2004
....
- Human embryonic stem cells have a unique epigenetic signature
Marina Bibikova
Illumina, Inc, San Diego, California 92121, USA
Genome Res 16:1075-83. 2006
..Our results indicate that hES cells have a unique epigenetic signature that may contribute to their developmental potential...
- Transcriptome coexpression map of human embryonic stem cells
Huai Li
Bioinformatics Unit, Branch of Research Resources, National Institute on Aging, NIH, Baltimore, MD 21224, USA
BMC Genomics 7:103. 2006
..However, no systematic analysis has yet addressed whether gene expression in human ES cells may be regulated in chromosomal domains, and no chromosomal domains of coexpression have been identified...
- Microarray analysis of selected genes in neural stem and progenitor cells
Yongquan Luo
Laboratory of Neurosciences, Gerontology Research Center, National Institute on Aging, Room 4E02, 5600 Nathan Shock Drive, Baltimore, Maryland 21224, USA
J Neurochem 83:1481-97. 2002
....
- [Association of polymorphisms of human leucocyte antigen -DRB1 and -DQA1 allele with outcomes of hepatitis B virus infection in Han population of north China]
Liang ping Lu
Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 100005, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:134-42. 2006
..To assess the association of polymorphisms of human leucocyte antigen (HLA) -DRB1 and -DQA1 region allele with outcomes of hepatitis B virus (HBV) infection in Han population of north China...
- [Relationship between polymorphisms of vitamin D receptor gene and familial aggregation of HBsAg carriers]
Jing Shan
Institute of Hepatitis Research, Affiliated You an Hospital, Capital University of Medical Sciences, Beijing 100096, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:148-53. 2006
..To determine whether -Taq I T/C and -Fok I C/T polymorphisms of vitamin D receptor (VDR) gene are associated with the familial aggregation of hepatitis B virus (HBV) infection...
- A1166C polymorphism of the angiotensin II type 1 receptor gene and essential hypertension in Han, Tibetan and Yi populations
Ying Liu
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, PR China
Hypertens Res 25:515-21. 2002
..A1166C polymorphism of the AT1R gene is probably not involved in the pathogenesis of essential hypertension in Han or Yi populations...
- [Association between genetic polymorphism of tumor necrosis factor and chronic severe hepatitis B in patients]
Zhuo Li
Hepatitis Institute, Beijing You An Hospital, Capital University of Medical Sciences, Beijing 100069, China
Zhonghua Yi Xue Za Zhi 87:2105-8. 2007
..To investigate the association between the single nucleotide polymorphisms (SNPs) of tumor necrosis factor (TNF-alpha) and chronic severe hepatitis B...
- [Relationship between HLA-DQA1, -DQB1 genes polymorphism and susceptilibity to bronchial asthma among Northern Hans]
Jinming Gao
Departemnt of Respiratory Disease, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Zhonghua Yi Xue Za Zhi 82:379-83. 2002
..To investigate the relationship between human leukocyte antigen (HLA)- DQA1, -DQB1 genes polymorphism and susceptibility to bronchial asthma among the Hans in the northern China...
- Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research
Richard Josephson
GlobalStem, Inc, 6 Taft Court, Rockville, Maryland 20850, USA
Stem Cells 25:437-46. 2007
..On the basis of global gene and microRNA expression, 2102Ep is somewhat less similar to hESC than the alternatives; however, 2102Ep expresses more hESC-associated microRNAs than NTERA-2 does, and fewer markers of differentiated fates...
- Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue
Soojung Shin
Stem Cells and Regenerative Medicine, Invitrogen, Carlsbad, California, USA
Stem Cells 25:1298-306. 2007
..Disclosure of potential conflicts of interest is found at the end of this article...
- Single nucleotide polymorphisms in the proximal promoter region of apolipoprotein M gene (apoM) confer the susceptibility to development of type 2 diabetes in Han Chinese
Nifang Niu
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, PR China
Diabetes Metab Res Rev 23:21-5. 2007
..In the present study, we investigated the potential association of apoM genetic variation with the development of T2D...
- BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation
Xianmin Zeng
Cellular Neurobiology Branch, National Institute on Drug Abuse and NIH, DHHS, Baltimore, MD 21224, USA
Restor Neurol Neurosci 22:421-8. 2004
..To explore a karyotypically abnormal variant human embryonic stem cell (hESC) line, BG01V, as a potential model for studies of dopaminergic neuronal differentiation...
- Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001
Sandii N Brimble
BresaGen, Inc, Athens, GA 30605, USA
Stem Cells Dev 13:585-97. 2004
..BG01, BG02, and BG03 hESCs are therefore independent, undifferentiated, and pluripotent lines that can be maintained without accumulation of karyotypic abnormalities...
- The association of the PAX4 gene with type 1 diabetes in Han Chinese
Yun Zhang
Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
Diabetes Res Clin Pract 81:365-9. 2008
..In present study, we aimed to evaluate whether the paired box gene 4 (PAX4) may play a role in the pathogenesis of type 1 diabetes (T1D) in Chinese Han population...
- Polymorphisms of renin-angiotensin system in essential hypertension in Chinese Tibetans
Bei Sun
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences Peking Union Medical College, Beijing 100005, China
Biomed Environ Sci 17:209-16. 2004
..To evaluate the potential implications of the genetic variability of angiotensin converting enzyme, angiotensinogen and angiotensin II type 1 receptor gene for essential hypertension in Tibetan...
- Genomic alterations in cultured human embryonic stem cells
Anirban Maitra
McKusick-Nathans Institute of Genetic Medicine, Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Nat Genet 37:1099-103. 2005
....
- [Association of polymorphism of human beta 2-adrenergic receptor gene and bronchial asthma]
Jin Ming Gao
Department of Respiratory Disease, PUMC Hospital, CAMS, PUMC, Beijing 100730, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 24:626-31. 2002
....
- Association between HLA-DQA1, -DQB1 gene polymorphisms and susceptibility to asthma in northern Chinese subjects
Jinming Gao
Department of Respiratory Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
Chin Med J (Engl) 116:1078-82. 2003
..This study was conducted to investigate whether susceptibility or resistance to asthma is associated with HLA-DQA1 and DQB1 genes polymorphism...
- Assessing self-renewal and differentiation in human embryonic stem cell lines
Jingli Cai
Laboratory of Neurosciences, National Institute on Aging, Department of Health and Human Services, Baltimore, Maryland, USA
Stem Cells 24:516-30. 2006
..We show that qPCR, with as few as 12 selected genes, can reliably distinguish differentiated cells from undifferentiated hESC populations...
- Modeling nonlinearity in dilution design microarray data
Xiuwen Zheng
Department of Mathematical Sciences, University of Texas at Dallas, Richardson, TX 75083 0688, USA
Bioinformatics 23:1339-47. 2007
..Furthermore, a new adjusted fold change (adj-FC) was proposed to predict the true FC without nonlinearity, in particular for large FC...
- The PPARD gene may be associated with schizophrenia in a Chinese population
Shi Long Sun
Psychiatr Genet 18:253-4. 2008
- Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails
Ying Liu
Biochemistry 47:6403-17. 2008
..They do not form heterodimers like TAFII250. It suggests that Brd4 should have its own mechanism to reinforce its chromatin association both in mitotic retention and related cellular regulation...
- Endothelin-3 growth factor levels decreased in cervical cancer compared with normal cervical epithelial cells
De Jun Sun
Gene Therapy Program, Sidney Kimmel Cancer Center, San Diego, CA 92121, USA
Hum Pathol 38:1047-56. 2007
..These results suggest that the reduction of ET-3 growth factor levels may be important in the transition from normal to cancerous cervical epithelium...
- A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci
Ying Liu
Division of Human Genetics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri, United States of America
PLoS Genet 4:e1000041. 2008
..This region harbors the interleukin 2 (IL2) and interleukin 21 (IL21) genes and was recently shown to be associated with four autoimmune diseases (Celiac disease, Type 1 diabetes, Grave's disease and Rheumatoid Arthritis)...
- Cyclic adenosine 3',5'-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription
Ying Liu
Section on Endocrine Physiology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Endocrinology 149:3512-20. 2008
..In addition, the data indicate that phosphorylated CREB is essential but not sufficient for activation of CRH transcription, suggesting that full promoter stimulation requires the interaction of phosphorylated CREB with a coactivator...
- Biomarker discovery and visualization in gene expression data with efficient generalized matrix approximations
Wenyuan Li
Department of Computer Science, University of Texas at Dallas, Richardson, TX 75083, USA
J Bioinform Comput Biol 5:251-79. 2007
..Based on the mechanism of matrix approximation, we further propose an algorithm, CBiomarker, to discover compact biomarker by reducing the redundancy...
- Investigate the role of PTEN in chemotaxis of human breast cancer cells
Wuzhou Wan
Beijing National Laboratory for Molecular Sciences BNLMS, Department of Chemical Biology, and State Key Laboratory of Molecular Dynamic and Stable Structures, College of Chemistry, Peking University, Beijing, China
Cell Signal 19:2227-36. 2007
..Taken together, our data show that PTEN plays a non-redundant role in EGF-induced chemotaxis of human breast cancer cells, and an optimal level of PTEN is required in these responses...
- Protection against human immunodeficiency virus type 1 Tat neurotoxicity by Ginkgo biloba extract EGb 761 involving glial fibrillary acidic protein
Wei Zou
Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, USA
Am J Pathol 171:1923-35. 2007
....
- Localization and mutation detection for paroxysmal kinesigenic choreoathetosis
Te Du
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 5 Dongdan 3 Tiao, Beijing 100005, China
J Mol Neurosci 34:101-7. 2008
..Paroxysmal kinesigenic choreoathetosis (PKC) is an autosomal-dominant movement disorder characterized by attacks of paroxysmal involuntary movements. To date, the causative gene has not been discovered...
- [278C > T variant of the alpha-1, 3-galactosyltransferase allele responsible for Bw subgroup]
Xian-guo Xu
Institute of Transfusion Medicine, Blood Center of Zhejiang Province, Key Laboratory of Blood Safety Research, Ministry of Health, Hangzhou, Zhejiang, 310006, P. R. China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 23:631-4. 2006
..CONCLUSION: A novel Bw allele (278 C to T) responsible for Bw variant is reported in Chinese population...
- [Dynamic pattern of gene expression in rat hearts responding to transient ischemia/reperfusion detected by cDNA microarray and cluster analysis]
Can Yuan
Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha 410078, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 29:252-6. 2004
..To analyze the pattern of gene expression programs during rat myocardial ischemia/reperfusion at multiple time points...
- Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes
Jason F Talbott
The MD PhD Program, University of Louisville, Louisville, KY 40292, USA
Exp Neurol 192:11-24. 2005
..In vivo electrophysiology demonstrated a limited and unsustained functional recovery concurrent with endogenous remyelination following EB-induced lesions...
- Protein kinase A regulates cell cycle progression of mouse fertilized eggs by means of MPF
Bingzhi Yu
Department of Biochemical and Molecular Biology, China Medical University, Shenyang, Liaoning, People s Republic of China
Dev Dyn 232:98-105. 2005
..Our results show that PKA, by inhibiting MPF, regulates cell cycle progression of fertilized eggs...
- Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer
Ying Liu
ICRF Molecular Oncology Laboratories, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK
Oncogene 21:387-99. 2002
..Clonogenic assays were performed by transfecting the full-length gene in to ovarian cancer cell lines and no suppression of growth was observed...
- Text mining functional keywords associated with genes
Ying Liu
College of Computing, Georgia Institute of Technology, Atlanta, GA 30332, USA
Stud Health Technol Inform 107:292-6. 2004
..We feel that this approach is general enough to apply to medical and biological literature to find other relationships: drugs vs. genes, risk-factors vs. genes, etc...
- [Variations of water-soluble carbohydrate and nitrogen contents in Leymus chinensis and Phragmites communis under different stocking rates]
Ying Liu
Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China
Ying Yong Sheng Tai Xue Bao 14:2167-70. 2003
..Proper stocking rates could stimulate the assimilation of nitrogen in soil, and bring it to the ground, which improved the nutrition value of the herbage...
- [Identification on genuine and pseudo shayuanzi collected from different place by HPLC fingerprint]
Yu Jie Zhang
Beijing University of Traditional Chinese Medicine, Beijing 100102, China
Zhongguo Zhong Yao Za Zhi 28:820-2, 861. 2003
..To establish the identification method for genuine and pseudo Shayuanzi by HPLC fingerprint...
- Nutritional genomics in yeast models
Ying Liu
Institute of Human Nutrition, Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Nutrition 20:166-72. 2004
- Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord
Ying Liu
Laboratory of Neurosciences, National Institute on Aging, Baltimore, Maryland 21224, USA
Glia 45:67-74. 2004
....
- Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples
Kimio Yoshimura
Cancer Information and Epidemiology Division, National Cancer Center Research Institute, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
J Hum Genet 48:654-8. 2003
..In the present study, the Japanese allele frequencies were verified by using nationwide population samples...
- [Screen selection of target genes regulated by HSF1 in heat shock response from myocardium of gene knockout mice]
Ying Liu
Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha 410078, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 29:1-5. 2004
..The 5 down-regulated genes and 6 up-regulated ones were shown to contain HSE in their promoter regions. CONCLUSION: In heat shock response, expression of multiple genes is regulated directly or indirectly by HSF1...
- Sources and distribution of aliphatic and polyaromatic hydrocarbons in sediments of Jiaozhou Bay, Qingdao, China
Xu Chen Wang
Department of Marine Ecology and Environmental Studies, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
Mar Pollut Bull 52:129-38. 2006
..In comparison to other polluted coastal sediments, the level of contamination from both aliphatic hydrocarbons and PAHs in Jiaozhou Bay sediments is relatively low at the present time...
- Effect of earthworms (Eisenia fetida) on the fractionation and bioavailability of rare earth elements in nine Chinese soils
Bei Wen
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing 100085, China
Chemosphere 63:1179-86. 2006
..The biomass and the concentrations of REEs in wheat shoots and roots increased after the treatment with earthworms. The results demonstrated that earthworm activity increased the mobility and bioavailability of REEs in soils...
- Genome-wide atlas of gene expression in the adult mouse brain
Ed S Lein
Allen Institute for Brain Science, Seattle, Washington 98103, USA
Nature 445:168-76. 2007
..This highly standardized atlas provides an open, primary data resource for a wide variety of further studies concerning brain organization and function...
- Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells
Yu Sun
Bioinformatics Unit, Research Resources Branch, National Institute on Aging, National Institutes of Health, 333 Cassall Drive, Baltimore, MD 21224, USA
Genomics 89:22-35. 2007
..The data and analyses resulting from this study provide a framework for new hypotheses and research directions and a public resource for functional genomics of ESCs...
- Text mining biomedical literature for discovering gene-to-gene relationships: a comparative study of algorithms
Ying Liu
College of Computing, Georgia Institute of Technology, 801 Atlantic Drive, Atlanta, GA 30322, USA
IEEE/ACM Trans Comput Biol Bioinform 2:62-76. 2005
..BEA-PARTITION is simple to implement and provides a powerful approach to clustering genes or to any clustering problem where starting matrices are available from experimental observations...
- The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
Leming Shi
National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA
Nat Biotechnol 24:1151-61. 2006
..This study provides a resource that represents an important first step toward establishing a framework for the use of microarrays in clinical and regulatory settings...
- Association of-238G/A and -857C/T polymorphisms of tumor necrosis factor-alpha gene promoter region with outcomes of hepatitis B virus infection
Hong quan Li
Department of Epidemiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, China
Biomed Environ Sci 19:133-6. 2006
..To determine whether -238G/A and -857C/T polymorphisms of tumor necrosis factor-alpha (TNF-alpha) gene promoter were associated with outcomes of hepatitis B virus infection...
- [Advances in researches on single-nucleotide polymorphisms of candidate genes for type 2 diabetes]
Yang Liu
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 100005, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:294-7. 2006
..This article introduces the strategies of SNP studies and reviews the SNP studies of major candidate genes for type 2 diabetes...
- Human protein tau represses DNA replication in vitro
Wen Li
The State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing 100101, China
Biochim Biophys Acta 1726:280-6. 2005
..However, tau did not repress the yield of RNA in transcription, suggesting that tau was replaced or ejected from the template by the elongating T7 RNA polymerase...
- Massively parallel signature sequencing profiling of fetal human neural precursor cells
Jingli Cai
Stem Cell Biology Unit/Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
Stem Cells Dev 15:232-44. 2006
..In addition, our results allow us to identify novel genes expressed in fNPCs and provide a detailed profile of fNPCs...
- Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers
Michelle Gaasenbeek
Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, London WC2A 3PX, UK
Cancer Res 66:3471-9. 2006
..These data suggest that CIN is not synonymous with copy number change and some cancers have a specific tendency to whole-chromosome deletion and regain or to mitotic recombination...
- Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research
Todd W Plaia
Stem Cell Center, American Type Culture Collection, 10801 University Boulevard, Manassas, Virginia 20110, USA
Stem Cells 24:531-46. 2006
....
- [Abdominal and pelvic lymph nodes in non-Hodgkin lymphoma: the nodal distribution in Chinese patients]
Ning Wu
Department of Diagnostic Radiology, Cancer Institute (Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
Zhonghua Zhong Liu Za Zhi 24:580-4. 2002
..The anatomic distribution of abdominal and pelvic lymph nodes in NHL of Chinese patients is different from that of the western countries...
