Stroke subtypes among young patients with systemic lupus erythematosusEswar Krishnan
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Am J Med 118:1415. 2005
..Little is known about subtypes of stroke in lupus...
Impact of age and comorbidities on the criteria for remission and response in rheumatoid arthritisE Krishnan
Arthritis and Osteoporosis Centre, 401 Buttonwood, West Reading, PA 19611, USA
Ann Rheum Dis 64:1350-2. 2005
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Percentile benchmarks in patients with rheumatoid arthritis: Health Assessment Questionnaire as a quality indicator (QI)Eswar Krishnan
Clinical Research Center of Reading, West Reading, PA, USA
Arthritis Res Ther 6:R505-13. 2004
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Declines in mortality from acute myocardial infarction in successive incidence and birth cohorts of patients with rheumatoid arthritisEswar Krishnan
Stanford University, Division of Immunology, Department of Medicine, 1000 Welch Rd, Suite 203, Palo Alto, Calif, USA
Circulation 110:1774-9. 2004
..The impact of this on atherosclerotic cardiovascular diseases is not known...
Systemic sclerosis mortality in the United States: 1979-1998Eswar Krishnan
Department of Medicine, Division of Rheumatology and Clinical Immmunology, University of Pittsburgh, Pittsburgh, PA, USA
Eur J Epidemiol 20:855-61. 2005
..This rise occurred during a period in which post-diagnosis survival of SSc is known to have increased, suggesting an increasing incidence of this disease...
Measuring effectiveness of drugs in observational databanks: promises and perilsEswar Krishnan
Division of Immunology, Department of Medicine, Stanford University, Palo Alto, CA, USA
Arthritis Res Ther 6:41-4. 2004
..An international metaRegister and a formal mechanism for standardizing and sharing drug data could help improve the utility of databanks. Medical journals have a vital role in enforcing a quality checklist that improves reporting...
Normative values for the Health Assessment Questionnaire disability index: benchmarking disability in the general populationEswar Krishnan
Stanford University, Palo Alto, California, USA
Arthritis Rheum 50:953-60. 2004
..This study was undertaken to establish normative values for the HAQ DI in a general population and to analyze its correlates...
Smoking, gender and rheumatoid arthritis-epidemiological clues to etiology. Results from the behavioral risk factor surveillance systemEswar Krishnan
Clinical Research Center of Reading, 401 Buttonwood St, West Reading, PA 19611, USA
Joint Bone Spine 70:496-502. 2003
..This study was undertaken to confirm and extend our earlier observation that gender is a biological effect modifier of smoking-rheumatoid arthritis (RA) relationship in a diverse national survey sample in the United States...
Smoking-gender interaction and risk for rheumatoid arthritisEswar Krishnan
Department of Medicine, Stanford University, Palo Alto, California, USA
Arthritis Res Ther 5:R158-62. 2003
..We conclude that sex is a biologic effect modifier in the association between smoking and rheumatoid arthritis. The role of menopause in the etiology of rheumatoid arthritis merits further research...
Hospitalizations and mortality in systemic sclerosis: results from the Nationwide Inpatient SampleL Chung
Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA
Rheumatology (Oxford) 46:1808-13. 2007
..To study the causes of hospitalizations and predictors of subsequent adverse outcomes for contemporary cohorts of patients with systemic sclerosis (SSc) in the USA...
Ethnicity and mortality from systemic lupus erythematosus in the USE Krishnan
Division of Rheumatology, Department of Medicine, University of Pittsburgh, S709 BST South, 3500 Terrace St, Pittsburgh, PA 15261, USA
Ann Rheum Dis 65:1500-5. 2006
..To study ethnic differences in mortality from systemic lupus erythematosus (lupus) in two large, population-based datasets...
Characterizing systemic sclerosis in Northern California: focus on Asian and Hispanic patientsG Schmajuk
Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA
Clin Exp Rheumatol 27:22-5. 2009
..The purpose of this study is to compare the clinical features of a group of Asian, Hispanic, and Caucasian patients with SSc in Northern California...
Reduction in long-term functional disability in rheumatoid arthritis from 1977 to 1998:a longitudinal study of 3035 patientsEswar Krishnan
Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94304, USA
Am J Med 115:371-6. 2003
..This decline is consistent with a beneficial effect of the associated changes in treatment strategies...
Hospitalization and mortality of patients with systemic lupus erythematosusEswar Krishnan
Division of Rheumatology, Department of Medicine, University of Pittsburgh, Pennsylvania 15261, USA
J Rheumatol 33:1770-4. 2006
..To describe hospitalization and mortality outcomes of patients with systemic lupus erythematosus (SLE) in the general population...
Attrition bias in rheumatoid arthritis databanks: a case study of 6346 patients in 11 databanks and 65,649 administrations of the Health Assessment QuestionnaireEswar Krishnan
Division of Rheumatology, Department of Medicine, Stanford University, Palo Alto, California, USA
J Rheumatol 31:1320-6. 2004
..Patient dropout (attrition) can bias and threaten validity of databank-based studies. Although there are several databanks of rheumatoid arthritis (RA) in operation, this phenomenon has not been well studied...
Patient questionnaires and formal education level as prospective predictors of mortality over 10 years in 97% of 1416 patients with rheumatoid arthritis from 15 United States private practicesTheodore Pincus
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-4500, USA
J Rheumatol 31:229-34. 2004
..This study shows that it is possible to account for more than 95% of patients over 10 years using mailed questionnaires to monitor patient status...
Obstetric hospitalizations in the United States for women with systemic lupus erythematosus and rheumatoid arthritisEliza F Chakravarty
Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California, USA
Arthritis Rheum 54:899-907. 2006
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Serum uric acid level and risk for peripheral arterial disease: analysis of data from the multiple risk factor intervention trialJoshua F Baker
Department of Medicine, University of Pennsylvania, USA
Angiology 58:450-7. 2007
..A history of gouty arthritis is an independent and statistically significant predictor of incidence of PAD even after adjustment for the effect of underlying hyperuricemia...
Systemic lupus erythematosus, rheumatoid arthritis, and postarthroplasty mortality: a cross-sectional analysis from the nationwide inpatient sampleRobyn T Domsic
Stanford University School of Medicine, Palo Alto, CA 94304, USA
J Rheumatol 37:1467-72. 2010
..Systemic lupus erythematosus (SLE) is a disease of considerable morbidity, and this may place patients at greater risk for poor in-hospital postoperative outcomes for procedures such as arthroplasty. Our aim was to test this hypothesis...
Hyperuricemia and incident heart failureEswar Krishnan
Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
Circ Heart Fail 2:556-62. 2009
..However, the relationship between hyperuricemia and the risk for incidence of heart failure in a community-based population has not been studied...
Progress in assessing physical function in arthritis: PROMIS short forms and computerized adaptive testingJames F Fries
Department of Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA
J Rheumatol 36:2061-6. 2009
..IRT-based instruments can improve measurement precision substantially over a wider range of disease severity. These modern methods were applied and the magnitude of improvement was estimated...
What constitutes progress in assessing patient outcomes?James F Fries
Stanford University School of Medicine, Palo Alto, CA 94304, USA
J Clin Epidemiol 62:779-80. 2009
..Another limitation is the degree of measurement error, the signal-to-noise ratio. These two issues drive down the statistical power of clinical trials and increase their expense...
Gout in ambulatory care settings in the United StatesEswar Krishnan
Division of Rheumatology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Rheumatol 35:498-501. 2008
..To describe the ambulatory care utilization by patients with gouty arthritis (gout) in the United States using a nationally representative sample...
Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug developmentJames F Fries
Stanford University School of Medicine, Palo Alto, California, USA
Arthritis Res Ther 6:R250-5. 2004
..We propose a principle of 'positive expected outcomes', which informs the assessment that a trial is ethical, together with a restatement of the priority of personal autonomy...
Factors associated with patients who leave acute-care hospitals against medical adviceSaid A Ibrahim
Center for Health Equity Research and Promotion, Veterans Administration Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
Am J Public Health 97:2204-8. 2007
..We examined hospital- and patient-related factors associated with discharge against medical advice (termed self-discharge) after emergency admission to acute-care hospitals...
Primary knee and hip arthroplasty among nonagenarians and centenarians in the United StatesEswar Krishnan
University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Arthritis Rheum 57:1038-42. 2007
..This report focuses on the poorly studied epidemiology and mortality outcomes of arthroplasty among these individuals...
Hyperuricemia and incidence of hypertension among men without metabolic syndromeEswar Krishnan
School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Hypertension 49:298-303. 2007
..09; 95% CI: 1.02 to 1.17). We conclude that the hyperuricemia-hypertension risk relationship is present among normotensive middle-aged men without diabetes/glucose intolerance or metabolic syndrome...
Gout and the risk of acute myocardial infarctionEswar Krishnan
University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Arthritis Rheum 54:2688-96. 2006
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Functional disability in rheumatoid arthritis patients compared with a community population in FinlandTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Arthritis Rheum 48:59-63. 2003
..To compare Health Assessment Questionnaire (HAQ) scores of patients with rheumatoid arthritis (RA) with HAQ scores from a sex- and age-adjusted population...
Rheumatoid arthritis: radiographic progression is getting milderEswar Krishnan
J Rheumatol 32:195; author reply 195. 2005
Gout and coronary artery disease: epidemiologic cluesEswar Krishnan
S709 BST South, 3500 Terrace Street, Pittsburgh, PA 15215, USA
Curr Rheumatol Rep 10:249-55. 2008
..Although there are gaps in evidence pointing to a causative pathway, overall, evidence exists for a relationship between gouty arthritis and coronary artery disease independent of traditional risk factors...
Early and extensive erosiveness in peripheral joints predicts atlantoaxial subluxations in patients with rheumatoid arthritisMarko Henrik Neva
Division of Orthopaedic and Trauma Surgery, Department of Surgery, Tampere University Hospital, Tampere, Finland
Arthritis Rheum 48:1808-13. 2003
..e., vertical subluxation) in patients with rheumatoid arthritis (RA) who were treated early and continuously with disease-modifying antirheumatic drugs for 8-13 years...
Unregistered trials are unethicalEswar Krishnan
PLoS Med 2:e48. 2005