Research Topics
Species | Kyoung HeoSummaryAffiliation: Yonsei University Country: Korea Publications
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Detail Information
Publications
Efficacy and safety of levetiracetam as adjunctive treatment of refractory partial seizures in a multicentre open-label single-arm trial in Korean patientsKyoung Heo
Department of Neurology, Severance Hospital, Seoul, Republic of Korea
Seizure 16:402-9. 2007..Three most common AEs were somnolence (36%), dizziness (12%), and headache (8%). Adjunctive LEV therapy was effective and well-tolerated in Korean adults with refractory partial epilepsy...- Patient awareness of complex partial seizuresKyoung Heo
Department of Neurology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
Epilepsia 47:1931-5. 2006..To assess self-awareness of complex partial seizures (CPSs) in unselected epilepsy patients through a thorough interview... - Single-photon emission computed tomography in a patient with ictal metamorphopsiaKyoung Heo
Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea
Seizure 13:250-3. 2004..The result suggests that the anatomical substrate involved in the generation of ictal facial metamorphopsia is located in the visual association areas at the right temporo-occipital junction... - The effect of topiramate monotherapy on bone mineral density and markers of bone and mineral metabolism in premenopausal women with epilepsyKyoung Heo
Department of Neurology, Yonsei University College of Medicine, Seodaemungu, Seoul, Korea
Epilepsia 52:1884-9. 2011..To investigate the effect of topiramate on bone mass and metabolism in premenopausal women with epilepsy... - Pregabalin add-on therapy using a flexible, optimized dose schedule in refractory partial epilepsies: a double-blind, randomized, placebo-controlled, multicenter trialByung In Lee
Department of Neurology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
Epilepsia 50:464-74. 2009..To evaluate the efficacy and safety of pregabalin (PGB) as adjunctive therapy, using a flexible-dosing schedule in Korean patients with refractory partial-onset seizures... - Diffusion tensor MRI visualizes decreased subcortical fiber connectivity in focal cortical dysplasiaSeung-Koo Lee
Department of Radiology, Yonsei University College of Medicine, 134 Shinchondong, Seodaemungu, Seoul 120-752, South Korea
Neuroimage 22:1826-9. 2004..DTI has high potential to be applied to localize the FCD and to provide a better understanding of the pathological changes in the white matter... - Clinical feasibility of immediate overnight switching from slow-release carbamazepine to oxcarbazepine in Korean patients with refractory partial epilepsySang Ahm Lee
Department of Neurology, University of Ulsan, Seoul, Republic of Korea
Seizure 19:356-8. 2010..The only clinical variable related to the failure of overnight switching was the number of seizures at baseline... - Interictal epileptiform discharges relate to 1H-MRS-detected metabolic abnormalities in mesial temporal lobe epilepsySun Ah Park
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
Epilepsia 43:1385-9. 2002.... - Long-term efficacy and tolerability of topiramate as add-on therapy in refractory partial epilepsy: an observational studyYang Je Cho
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
Epilepsia 50:1910-9. 2009..To evaluate the long-term efficacy and tolerability of topiramate (TPM) as add-on therapy in patients with refractory partial epilepsy... - Short-term efficacy and safety of zonisamide as adjunctive treatment for refractory partial seizures: a multicenter open-label single-arm trial in Korean patientsKyoung Heo
Department of Neurology, Severance Hospital, Seoul, Republic of Korea
Seizure 21:188-93. 2012..To evaluate the efficacy and safety of adjunctive zonisamide (ZNS) therapy in Korean adults with uncontrolled partial epilepsy... - Cognitive and behavioral effects of lamotrigine and carbamazepine monotherapy in patients with newly diagnosed or untreated partial epilepsySang Ahm Lee
Department of Neurology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Republic of Korea
Seizure 20:49-54. 2011..In this prospective study, we compared the long-term cognitive and behavioral effects of lamotrigine (LTG) and carbamazepine (CBZ) in patients with newly diagnosed or untreated partial epilepsy... - Relationship between bilateral temporal hypometabolism and EEG findings for mesial temporal lobe epilepsy: analysis of 18F-FDG PET using SPMMi Ae Kim
Department of Neurology, Yonsei University College of Medicine, Severance Hospital, Shinchon-dong 134, Seoul 120-752, Republic of Korea
Seizure 15:56-63. 2006..Our results suggest that analysis of 18F-FDG PET by using SPM may have a role in predicting those patients with bitemporal excitability or bitemporal independent epileptogenicity, and these patients should be monitored carefully... - Antiepileptic drug withdrawal after successful surgery for intractable temporal lobe epilepsyYoung Dae Kim
Department of Neurology, Yonsei University of Medicine, Seoul, Korea
Epilepsia 46:251-7. 2005..Younger age at the time of surgery and a shorter disease duration seem to affect successful AED discontinuation for a long-term period... - Balloon cells and dysmorphic neurons in the hippocampus associated with epileptic amnesic syndrome: a case reportSe Hoon Kim
Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea
Epilepsia 49:905-9. 2008..To our knowledge, this is the first reported case showing AHS with balloon cells. The presence of balloon cells reinforces the hypothesis that AHS itself might be a maldevelopment disorder... - Diffusion tensor MRI and fiber tractography of cerebellar atrophy in phenytoin usersSeung Koo Lee
Department of Radiology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, Seoul 120 752, Korea
Epilepsia 44:1536-40. 2003..The purpose of this study was to investigate the afferent fiber system to the cerebellum in patients with phenytoin (PHT)-induced cerebellar atrophy in comparison with cerebellar atrophy of other etiologies by using DT-MRI... - Neurocutaneous melanosis presenting as chronic partial epilepsyByoung Seok Ye
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
J Clin Neurol 4:134-7. 2008..Chronic partial epilepsy as a sole manifestation is rare in NCM... - Chronic activation of CREB and p90RSK in human epileptic hippocampusSun Ah Park
Department of Neurology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, CPO Box 8044, Seoul 120 752, Korea
Exp Mol Med 35:365-70. 2003..Our results demonstrate that chronic activation CREB and p90RSK in the epileptic hippocampus may be closely associated with the histopathological changes of AHS... - A nonsynonymous variation in MRP2/ABCC2 is associated with neurological adverse drug reactions of carbamazepine in patients with epilepsyWon Joo Kim
Departments of Pharmacology, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, 134 Sinchon dong, Seoul, Korea
Pharmacogenet Genomics 20:249-56. 2010..Therefore, genetic variations in the MRP2 gene may affect individual drug responses to the antiepileptic agent carbamazepine... - Syndromic diagnosis at the epilepsy clinic: role of MRI in lobar epilepsiesByung In Lee
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
Epilepsia 43:496-504. 2002..This study was conducted to incorporate MRI features into the international classification of epilepsies and epilepsy syndromes (ICEES) proposed by the International League Against Epilepsy (ILAE)... - Comparison of temporal lobectomies of children and adults with intractable temporal lobe epilepsyYun Jin Lee
Department of Pediatrics, Pediatric Epilepsy Clinic, Severance Children s Hospital, Brain Research Institute, College of Medicine, Yonsei University, Seoul, Republic of Korea
Childs Nerv Syst 26:177-83. 2010..The aim of the study was to assess the difference in clinical characteristics and postsurgical outcomes between children and adults who have undergone temporal lobectomy (TL)... - The localizing and lateralizing value of auras in lesional partial epilepsy patientsByoung Seok Ye
Department of Neurology, Yonsei University College of Medicine, 50 Yonsei ro, Seodaemun gu, Seoul 120 752, Korea
Yonsei Med J 53:477-85. 2012..Conclusion: Our results support the previously known localizing value of auras, and suggest that dysphasic auras and the association of emotional and autonomic auras may have a lateralizing value... - Palilalia, echolalia, and echopraxia-palipraxia as ictal manifestations in a patient with left frontal lobe epilepsyYang Je Cho
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
Epilepsia 50:1616-9. 2009..This result suggests that the neuroanatomic substrate involved in the generation of these behaviors as ictal phenomena might exist in the SMA of the left frontal lobe... - Determination of lamotrigine in human serum by high-performance liquid chromatography–tandem mass spectrometryWoonhyoung Lee
Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, South Korea
Neurol Sci 31:717-20. 2010..1–109.0 was used to quantify. The analytical measurement range is from 0.1 to 20 ?g/ml and the upper clinical reportable range is chosen to be 100 ?g/ml. The method was successfully employed in a clinical application... - Post-transfusion posterior leukoencephalopathy with cytotoxic and vasogenic edema precipitated by vasospasmKyoung Heo
Department of Neurology, Yonsei University College of Medicine and Severance Hospital, Seoul, Korea
Cerebrovasc Dis 15:230-3. 2003 - Prominent cerebellar symptoms with unusual magnetic resonance imaging findings in acquired hepatocerebral degenerationSun Ah Park
Department of Neurology, Soonchunhyang University Bucheon Hospital, 1174 Jung-dong, Wonmi-gu, Bucheon, Gyeonggido 420-767, South Korea
Arch Neurol 61:1458-60. 2004..Findings from our patient suggest that dominant cerebellar deficits with compatible T2 high-signal lesions are another type of clinical manifestation in AHCD... - Coma probably induced by lorazepam-valproate interactionSang Ahm Lee
Department of Neurology and Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Seizure 11:124-5. 2002..However, it remains unknown whether this drug interaction is clinically significant. We report a patient with epilepsy who showed that VPA-LZP interaction could result in severe encephalopathy such as coma... - Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in miceKyoung Heo
Department of Neurology and Brain Korea 21 Project for Medical Science, Yonsei University, College of Medicine, 134 Sinchon-dong, Seodaemun-gu, 120-752 Seoul, Republic of Korea
Neurosci Lett 398:195-200. 2006..Thus, this study suggests that minocycline inhibits both caspase-dependent and -independent apoptotic pathways and may be neuroprotective against hippocampal damage after KA treatment...