Research Topics
| Tae S KimSummaryAffiliation: Korea University Country: Korea Publications
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Detail Information
Publications
Gene transfer of AIMP1 and B7.1 into epitope-loaded, fibroblasts induces tumor-specific CTL immunity, and prolongs the survival period of tumor-bearing miceTae S Kim
Laboratory of Immunology, School of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
Vaccine 26:5928-34. 2008..1/OVA cells significantly prolonged the survival period of EG7 tumor-bearing mice. These results indicate that AIMP1-secreting, epitope-loaded fibroblasts efficiently induce antigen-specific CTL responses in mice...- Differential enhancement of leukaemia cell differentiation without elevation of intracellular calcium by plant-derived sesquiterpene lactone compoundsS H Kim
School of Life Sciences and Biotechnology, Korea University, Seoul, Korea
Br J Pharmacol 155:814-25. 2008..Here, we investigated the effect of plant-derived sesquiterpene lactone compounds and their underlying mechanisms in ATRA-induced differentiation of human leukaemia HL-60 cells... - Prolongation of the survival of breast cancer-bearing mice immunized with GM-CSF-secreting syngeneic/allogeneic fibroblasts transfected with a cDNA expression library from breast cancer cellsTae S Kim
School of Life Sciences and Biotechnology, Korea University, Seoul 136 701, Republic of Korea
Vaccine 24:6564-73. 2006..As the transferred DNA is replicated as the transfected cells divide, the vaccine could be prepared from microgram quantities of tumor tissue... - Enhanced immunity to breast cancer in mice immunized with fibroblasts transfected with a complementary DNA expression library from breast cancer cells: Enrichment of the vaccine for immunotherapeutic cellsTae Sung Kim
School of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
J Immunother 29:261-73. 2006..The immunity, mediated by CD8+ T cells, was sufficient to prolong the survival of mice with established breast cancer... - Anti-CD3 single-chain Fv/interleukin-18 fusion DNA induces anti-mycobacterial resistance via efficient interferon-gamma production in BALB/c mice infected with Mycobacterium aviumSeung H Kim
School of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Republic of Korea
Vaccine 24:3365-73. 2006..These results indicate that vaccination with the pAnti-CD3sFv/IL-18 fusion DNA induces significant resistance to M. avium infection, via the production of IFN-gamma in CD4+ T cells... - Formononetin, a phyto-oestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activityJin Park
School of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
Immunology 116:71-81. 2005..These results suggest that phyto-oestrogens and some of their metabolites may increase allergic responses via the enhancement of IL-4 production in T cells... - Immunity to squamous carcinoma in mice immunized with dendritic cells transfected with genomic DNA from squamous carcinoma cellsInsug O-Sullivan
Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois 60612, USA
Cancer Gene Ther 12:825-34. 2005..Two independent in vitro cytotoxicity assays indicated the presence of robust cell-mediated immunity directed toward the SCC in mice immunized with the transfected cells... - Induction of persistent in vivo resistance to Mycobacterium avium infection in BALB/c mice injected with interleukin-18-secreting fibroblastsSu W Chung
Department of Pharmacy, College of Pharmacy, Chonnam National University, 500-757 Kwangju, Republic of Korea
Vaccine 22:398-406. 2004..This work suggests that IL-18-secreting fibroblasts may serve as a vehicle for paracrine secretion of IL-18 in immunotherapy of MAC infection... - Generation of tumor-specific cytotoxic T lymphocyte and prolongation of the survival of tumor-bearing mice using interleukin-18-secreting fibroblasts loaded with an epitope peptideSu W Chung
Department of Pharmacy, College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Kwangju 500-757, South Korea
Vaccine 22:2547-57. 2004..These results support the ability of IL-18/B7.1 gene transfer to enhance the antigen-presenting capacity of fibroblasts for inducing antigen-specific CTL response... - Exposure to 4-tert-octylphenol, an environmentally persistent alkylphenol, enhances interleukin-4 production in T cells via NF-AT activationMi H Lee
Immunology Laboratory, College of Pharmacy, Chonnam National University, Kwangju 500-757, South Korea
Toxicol Appl Pharmacol 197:19-28. 2004..These findings demonstrate that OP enhances IL-4 production in T cells via the stimulation of calcineurin-dependent NF-AT activation... - Induction of interleukin-12 production in mouse macrophages by berberine, a benzodioxoloquinolizine alkaloid, deviates CD4+ T cells from a Th2 to a Th1 responseTae S Kim
Drug Development, College of Pharmacy, Chonnam National University, Kwangju, Republic of Korea
Immunology 109:407-14. 2003..These findings may point to a possible therapeutic use of berberine or medicinal plants containing berberine in the Th type 2 cell-mediated immune diseases such as allergic diseases...