False-positive HIV-1 test results in a low-risk screening setting of voluntary blood donation. Retrovirus Epidemiology Donor StudyS Kleinman
Westat Inc, Rockville, MD, USA
JAMA 280:1080-5. 1998
..Persons at risk of human immunodeficiency virus 1 (HIV-1) infection, have been classified incorrectly as HIV infected because of Western blot results, but the frequency of false-positive Western blot results is unknown...
- Research, monitoring, and policy issues related to emerging pathogens
Steven Kleinman
U. British Columbia, Vancouver, BC, Canada
Vox Sang 83:351-4. 2002
- Frequency of HBV DNA detection in US blood donors testing positive for the presence of anti-HBc: implications for transfusion transmission and donor screening
Steven H Kleinman
Westat, Rockville, Maryland, USA
Transfusion 43:696-704. 2003
..An estimate of the rate of HBV DNA-positive, anti-HBc-positive units is important for evaluating the need for anti-HBc donor screening, especially in the context of HBV NAT...
- Hepatitis G virus biology, epidemiology, and clinical manifestations: Implications for blood safety
S Kleinman
University of British Columbia, Vancouver, British Columbia, Canada
Transfus Med Rev 15:201-12. 2001
..Because the data do not indicate any pathologic effects of HGV, it is not appropriate to screen the blood supply for HGV RNA...
- Comparison of demographic and donation profiles and transfusion-transmissible disease markers and risk rates in previously transfused and nontransfused blood donors
B Wang
Westat, Rockville, Maryland 20850, USA
Transfusion 44:1243-51. 2004
..Little is known, however, about the impact of indefinite deferral of transfused donors on blood safety and availability in the US...
- Initiatives to improve blood donor screening
S Kleinman
Professor of Clinical Pathology, University of British Columbia, Vancouver, BC, Canada
Dev Biol (Basel) 120:67-75. 2005
- Does prevalence of transfusion-transmissible viral infection reflect corresponding incidence in United States blood donors?
Baoguang Wang
Westat, Rockville, Maryland 20850, USA
Transfusion 45:1089-96. 2005
..Prevalence, however, is readily available. Understanding whether prevalence reflects corresponding incidence may help blood centers monitor disease risks...
- AABB survey of transfusion-related acute lung injury policies and practices in the United States
Patricia Kopko
Histocompatibility Laboratory, BloodSource, Sacramento, California, USA
Transfusion 47:1679-85. 2007
..Policies and practices with regard to transfusion-related acute lung injury (TRALI) diagnosis, laboratory investigation of TRALI cases, and donor deferral and donor management are not standardized...
- The development of West Nile virus safety policies by Canadian blood services: guiding principles and a comparison between Canada and the United States
Eleftherios C Vamvakas
Canadian Blood Services; Department of Pathology and Laboratory Medicine, University of Ottawa Faculty of Medicine, ON, Canada
Transfus Med Rev 20:97-109. 2006
..This review discusses the guiding principles affecting CBS policy development and compares CBS WNV safety policies to policies adopted in the United States...
- Promoting recognition and prevention of transfusion-related acute lung injury
Steven Kleinman
AABB (American Association of Blood Banks, Bethesda, MD 20814-2749, USA
Crit Care Nurse 27:49-53. 2007
- Correlates of hepatitis C virus (HCV) RNA negativity among HCV-seropositive blood donors
Michael P Busch
Blood Systems Research Institute, San Francisco, California 94118, USA
Transfusion 46:469-75. 2006
..Factors associated with resolution of viremia are not well defined. Implementation of routine nucleic acid testing (NAT) of blood donors has yielded a large data set for analysis of demographic correlates of resolved viremia...
- A perspective on transfusion-related acute lung injury two years after the Canadian Consensus Conference
Steven Kleinman
Transfusion 46:1465-8. 2006
- The 2003 West Nile virus United States epidemic: the America's Blood Centers experience
Steven Kleinman
Westat, Rockville, Maryland, USA
Transfusion 45:469-79. 2005
..This study demonstrates that a national collaborative effort facilitates timely surveillance of blood donor infectious disease prevalence rates...
- Toward an understanding of transfusion-related acute lung injury: statement of a consensus panel
Steven Kleinman
Kleinman Biomedical Research, Victoria, British Columbia, Canada
Transfusion 44:1774-89. 2004
- The donor notification process from the donor's perspective
Steven Kleinman
Westat, Rockville, Maryland, USA
Transfusion 44:658-66. 2004
..Despite large numbers of blood donors being notified of abnormal infectious disease screening results, there has been little scientific study of the effects of this process...
- Survival after transfusion as assessed in a large multistate US cohort
Steven Kleinman
Kleinman Biomedical Research, 1281 Rockcrest Avenue, Victoria, British Columbia V9A 4W4, Canada
Transfusion 44:386-90. 2004
..The only survival and mortality data on a general population of transfused patients in the United States is more than two decades old. More contemporary data are needed to reflect more current patient populations and transfusion practices...
- Transfusion transmission of West Nile virus: a merging of historical and contemporary perspectives
F Blaine Hollinger
Baylor College of Medicine, Houston, Texas, USA
Transfusion 43:992-7. 2003
- Risks associated with transfusion of cellular blood components in Canada
Steven Kleinman
University of British Columbia, Vancouver BC, Canada
Transfus Med Rev 17:120-62. 2003
..These estimates are useful for decisions concerning transfusion therapy, the informed consent process, and for evaluating efficacy of interventions to reduce risk...
- Performance characteristics of the Food and Drug Administration-licensed Roche Cobas TaqScreen West Nile virus assay
Anuradha Pai
From Roche Molecular Systems, Pleasanton, California 94588, USA
Transfusion 48:2184-9. 2008
..A series of studies established the performance characteristics of the assay and test system before FDA licensure...
