Research Topics
Species | Kwadwo A KoramSummaryAffiliation: Kenya Medical Research Institute Country: Kenya Publications
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Detail Information
Publications
Severe falciparum malaria in young children of the Kassena-Nankana district of northern GhanaAbraham R Oduro
Navrongo Health Research Centre, Navrongo, Ghana
Malar J 6:96. 2007..Children aged 6-59 months with diagnosis suggestive of acute disease were characterized using the standard WHO definition for severe malaria...- Understanding and retention of the informed consent process among parents in rural northern GhanaAbraham R Oduro
Navrongo Health Research Centre, Ghana Health Service, Box 114, Navrongo, Ghana
BMC Med Ethics 9:12. 2008..Parental informed consent process in a rural setting of northern Ghana was studied to describe comprehension and retention among parents as part of the evaluation of the existing informed consent process... - Seasonal profiles of malaria infection, anaemia, and bednet use among age groups and communities in northern GhanaKwadwo A Koram
Noguchi Memorial Institute for Medical Research, Legon, Accra, Ghana
Trop Med Int Health 8:793-802. 2003..There was a significantly lower risk of parasitaemia among infants [odds ratio (OR) 6-8] and young children (OR 3-4) living in the central, more urbanized sector of the study area... - Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in GhanaKwadwo A Koram
Epidemiology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana
Acta Trop 95:194-203. 2005..The findings are in agreement with current recommendations for using artemisinin-based combinations for treating uncomplicated malaria in areas of high CHQ failure such as Ghana... - Severe anemia in young children after high and low malaria transmission seasons in the Kassena-Nankana district of northern GhanaK A Koram
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon
Am J Trop Med Hyg 62:670-4. 2000..Although the relative contributions of other causes of severe anemia were not assessed, repeated malaria infections may be a primary determinant of severe anemia among infants and young children during the high transmission season... - Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria controlCollins K Ahorlu
Noguchi Memorial Institute for Medical Research, University of Ghana, Box LG581, Legon, Ghana
Malar J 8:292. 2009.... - Socio-cultural determinants of treatment delay for childhood malaria in southern GhanaCollins K Ahorlu
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana
Trop Med Int Health 11:1022-31. 2006..Effects on health seeking of illness-related experience and meaning are complex, and explaining their role may strengthen interventions for childhood malaria... - Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in GhanaCollins K Ahorlu
Noguchi Memorial Institute for Medical Research, University of Ghana, Box LG581, Legon, Ghana
Malar J 10:127. 2011..This paper reports persistence of reduced parasitaemia two years into the intervention. The baseline and year-one-evaluation findings were published earlier... - Antibody levels to multiple malaria vaccine candidate antigens in relation to clinical malaria episodes in children in the Kasena-Nankana district of Northern GhanaDaniel Dodoo
Department of Immunology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana
Malar J 10:108. 2011..The present study was done in under six year old children to identify malaria antigens which induce antibodies that correlate with protection from Plasmodium falciparum malaria... - Clinical case definitions and malaria vaccine efficacyWilliam O Rogers
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon
J Infect Dis 193:467-73. 2006..We suggest that clinical case definitions of malaria that incorporate a threshold parasitemia are arbitrary and do not yield stable estimates of vaccine trial end points... - HLA-DRB1*04 allele is associated with severe malaria in northern GhanaAwo D Osafo-Addo
Department of Epidemiology, Noguchi Memorial Institute for Medical Research, Accra, Ghana
Am J Trop Med Hyg 78:251-5. 2008..4%) and Nankam (4.7%), and the OR for the association between DRB1*04 and severe malaria was similar in both ethnic groups. These findings are consistent with results from Gabon suggesting that DRB1*04 is a risk factor for severe malaria... - Mutations in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance genes, and treatment outcomes in Ghanaian children with uncomplicated malariaNancy O Duah
Noguchi Memorial Institute for Medical Research, University of Ghana, P O Box LG581, Legon, Ghana
J Trop Pediatr 53:27-31. 2007..872 and a p-value = 0.027. All parasite isolates from samples taken at recrudescence from patients with chloroquine treatment failures were found to have both Pfcrt and Pfmdr mutations... - Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adultsDaniel Dodoo
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana
Malar J 10:168. 2011..Assessing T cell responses is especially challenging, given genetic restriction, low responses observed in endemic areas, their variability over time, potential suppression by parasitaemia and the intrinsic variability of the assays... - Community concepts of malaria-related illness with and without convulsions in southern GhanaCollins K Ahorlu
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana
Malar J 4:47. 2005..Inasmuch as the presence or absence of convulsions reportedly affects timely help-seeking for malaria, a local comparison of these conditions is needed to inform malaria control... - Malaria vaccine development: an endemic country perspectiveKwadwo A Koram
Department of Epidemiology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Ghana
Hum Vaccin 6:12-6. 2010..These and other challenges related to the development and deployment of an effective malaria vaccine especially as they concern endemic countries are discussed... - Antimalarial drug use among caregivers in GhanaBenjamin K Abuaku
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana
Afr Health Sci 4:171-7. 2004.... - Mefloquine treatment for uncomplicated falciparum malaria in young children 6-24 months of age in northern GhanaDavid J Fryauff
US Naval Medical Research Unit No 3, Cairo, Egypt
Am J Trop Med Hyg 76:224-31. 2007..An observed recurrent parasitemia of 34,400 trophozoites/microL against a MQ blood concentration of 550 ng/mL was taken as indication of tolerance to suppressive levels of the drug at this location... - The changing patterns of hypertension in Ghana: a study of four rural communities in the Ga DistrictJuliet Addo
National Diabetes Management and Research Centre, Korle Bu Teaching Hospital, Korle Bu, Ghana
Ethn Dis 16:894-9. 2006..To determine the prevalence, distribution and risk factors of hypertension among rural residents in Ghana... - Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malariaAnja T R Jensen
Centre for Medical Parasitology, Copenhagen University Hospital (Rigshospitalet) and Institute for Medical Microbiology and Immunology, University of Copenhagen, Copenhagen, Denmark
Infect Immun 71:4193-6. 2003..Our data call for circumspection regarding the molecular identity of the parasite ligand mediating adhesion to CSA in PAM... - A randomized, double-blind, placebo-controlled, dose-ranging trial of tafenoquine for weekly prophylaxis against Plasmodium falciparumBraden R Hale
US Navy Medical Research Unit No. 3, Cairo, Egypt
Clin Infect Dis 36:541-9. 2003..Tafenoquine dosages of 50, 100, and 200 mg/week were safe, well tolerated, and effective against P. falciparum infection in this study population... - Characteristics of severe anemia and its association with malaria in young children of the Kassena-Nankana District of northern GhanaSeth Owusu-Agyei
Navrongo Health Research Center, Ministry of Health, Navrongo, Upper East Region, Ghana
Am J Trop Med Hyg 67:371-7. 2002..Evidence suggests that dramatic peaks and troughs of severe anemia are regular and possibly predictable events that may be used to gauge the health and survival of young children in this area...