Attenti alle bufale ("beware of red herrings"), or, how to make evidence-based medicine work for youTom Jefferson
Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 99:625-7. 2006
Inactivated influenza vaccines in the elderly--are you sure?Tom Jefferson
Cochrane Vaccines Field, 15100 Alessandria, Italy
Lancet 370:1199-200. 2007
Implementing a guideline for the treatment of type 2 diabetics: results of a cluster-randomized controlled trial (C-RCT)Carla Perria
Community Health Unit, Lazio Region Public Health Agency, Rome, Italy
BMC Health Serv Res 7:79. 2007
..We assessed the effectiveness of different strategies for the implementation of an evidence-based guideline for the management of non-complicated type 2 diabetes among General Practitioners (GPs) of Lazio region...
Physical interventions to interrupt or reduce the spread of respiratory viruses: systematic reviewTom Jefferson
Acute Respiratory Infections Group, Cochrane Collaboration, Rome, Italy
BMJ 339:b3675. 2009
..To review systematically the evidence of effectiveness of physical interventions to interrupt or reduce the spread of respiratory viruses...
Influenza vaccination: policy versus evidenceTom Jefferson
Cochrane Vaccines Field, Anguillara Sabazia, Roma 00061, Italy
BMJ 333:912-5. 2006
Bufale spotting, part two: assessing systematic reviewsTom Jefferson
Cochrane Vaccines Field, Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 100:180-1. 2007
Bufale spotting, part three: assessing editorialsTom Jefferson
Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 100:267. 2007
Relation of study quality, concordance, take home message, funding, and impact in studies of influenza vaccines: systematic reviewT Jefferson
Cochrane Vaccines Field, ASL Azienda Sanitaria Locale AL 20, 15100 Alessandria, Italy
BMJ 338:b354. 2009
..To explore the relation between study concordance, take home message, funding, and dissemination of comparative studies assessing the effects of influenza vaccines...
Bufale spotting, Part 10: Assessing a journalTom Jefferson
Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 101:235-6. 2008
Bufale Spotting, part 9: assessing an economic evaluationTom Jefferson
Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 101:175-6. 2008
Antivirals for influenza in healthy adults: systematic reviewT Jefferson
Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
Lancet 367:303-13. 2006
..Use of antivirals is recommended for the control of seasonal and pandemic influenza. Our aim was to review the evidence of efficacy, effectiveness, and safety of registered antivirals against naturally occurring influenza in healthy adults...
Hepatitis B vaccination and multiple sclerosis: evidence from a systematic reviewV Demicheli
Cochrane Vaccines Field, Alessandria, Italy
J Viral Hepat 10:343-4. 2003
Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic reviewT Jefferson
Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
Lancet 365:773-80. 2005
..We aimed to assess evidence of efficacy and effectiveness of live attenuated and inactivated influenza vaccines in children up to 16 years of age...
Efficacy and effectiveness of influenza vaccines in elderly people: a systematic reviewT Jefferson
Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
Lancet 366:1165-74. 2005
..Influenza vaccination of elderly individuals is recommended worldwide. Our aim was to review the evidence of efficacy and effectiveness of influenza vaccines in individuals aged 65 years or older...
Influenza like Illness (ILI): prescribing behaviour of 83 sentry doctors in Lazio region in the period 2001-2002. Is it adherent to Italian ILI guidelines?L Orzella
Agency of Public Health ASP Lazio Region, Rome, Italy
Ann Ig 19:19-26. 2007
..Overall, doctors' attitude in prescribing is generally coherent with Italian Guidelines on ILI even though a high variability still persists...
Influenza vaccines in adultsT Jefferson
Health Reviews Ltd, Via Adige 28a, 00061 Anguillara Sabazia, Rome, Italy
Occup Med (Lond) 52:255-8. 2002
..As the yearly levels of circulating A and B viruses are difficult to predict during the decision time for a vaccination campaign, there is a considerable element of uncertainty regarding the likely effectiveness of 'this year's' vaccine...
Effectiveness of immune globulins in preventing infectious hepatitis and hepatitis A: a systematic reviewE Bianco
National Health Institute, Rome, Italy
Dig Liver Dis 36:834-42. 2004
..To assess the effectiveness and safety of immune globulins in preventing infectious hepatitis and hepatitis A...
Bufala spotting, part one: assessing research papersTom Jefferson
Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 100:38-9. 2007
Author's response to influenza vaccination: policy v evidenceTom Jefferson
BMJ 333:1172. 2006
Influenza vaccination for elderly people and their care workersTom Jefferson
Lancet 369:1857-8. 2007
A withdrawn prepublicationTom Jefferson
Lancet 369:901-2. 2007
Bufale spotting, part 8: assessing a letter to a journalTom Jefferson
Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
J R Soc Med 100:551. 2007
Detecting plagiarism: current quality control systems don't workTom Jefferson
BMJ 333:706. 2006
Quality of systematic reviews of economic evaluations in health careTom Jefferson
Cochrane Health Economics Group, Rome, Italy
JAMA 287:2809-12. 2002
..Measures taken by the research community to address the issue included the promulgation of guidelines and the publicizing of good practice in economic evaluation...
Polysaccharide pneumococcal vaccinesTom Jefferson
BMJ 325:292-3. 2002
The Brighton Collaboration: addressing the need for standardized case definitions of adverse events following immunization (AEFI)Jan Bonhoeffer
University Children s Hospital Basel, Basel, Switzerland
Vaccine 21:298-302. 2002
..Comparability requires the availability of standardized case definitions for adverse events following immunization (AEFI) and guidelines for case determination, recording and data presentation...
Economic analysis of influenza vaccination and treatmentTom Jefferson
Ann Intern Med 138:607; author reply 608-9. 2003
Balancing benefits and harms in health care: observational data on harm are already included in systematic reviewsTom Jefferson
BMJ 327:750. 2003
Informed choice and balance are victims of the MMR-autism sagaTom Jefferson
Lancet Infect Dis 4:135-6. 2004
The role of editorial peer review in the evaluation of vaccine safetyTom Jefferson
Cochrane Vaccines Field, 00061 Anguillara Sabazia, Rome, Italy
Vaccine 22:2073-5. 2004
Bioterrorism and compulsory vaccinationTom Jefferson
BMJ 329:524-5. 2004
A systematic approach to medical decision-making of uncommon clinical pictures: a case of ulcerative skin lesions by palm tree thorn injury and a one-year follow-upSalvatore Corrao
Unit of Clinical Methodology, Epidemiology and Statistics, A R N A S Civico e Benfratelli Hospital Trust, Palermo, Italy
Med Inform Internet Med 30:203-10. 2005
..The method we have proposed can be applied in every area of the world, especially in rural areas. Finally, an Internet-shared database of uncommon clinical pictures with critically appraised topics could be useful in saving more time...
[Evidence-based emergency pathways for patients with acute coronary syndrome]Stefania Cardo
Agenzia di Sanità Pubblica del Lazio
Ital Heart J 6:27S-40S. 2005
....
Streptococcus pneumoniae in western Europe: serotype distribution and incidence in children less than 2 years oldTom Jefferson
Cochrane Vaccines Field, Anguillara Sabazia, Rome, Italy
Lancet Infect Dis 6:405-10. 2006
..Thus the use of studies of vaccine effectiveness based on the US population may lead to an overestimation of the benefits of its introduction in Europe...
Measuring the quality of editorial peer reviewTom Jefferson
Health Reviews Ltd, Rome, Italy
JAMA 287:2786-90. 2002
..The research needed to understand the broader effects of peer review poses many methodologic problems and would require the cooperation of many parts of the scientific community...