Research Topics
Genomes and GenesSpecies | Takako MiyamaeSummaryAffiliation: Yokohama City University Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Effect of anakinra on arthropathy in CINCA/NOMID syndromeTakako Miyamae
Department of Pediatrics, Yokohama City University, Yokohama, Japan
Pediatr Rheumatol Online J 8:9. 2010..Furthermore, longitudinal growth of the femur and tibia was identified during 20 months of observation...
Efficacy of thalidomide in a girl with inflammatory calcinosis, a severe complication of juvenile dermatomyositisTakako Miyamae
Department of Pediatrics, Yokohama City University, 3 9 Fukuura, Kanazawaku, Yokohama 236 0004, Japan
Pediatr Rheumatol Online J 8:6. 2010..08 mg/dL. Recent examination by whole-body 18F-FDG-PET-CT over the 15 months of thalidomide treatment demonstrated fewer hot spots around the subcutaneous calcified lesions...
Cross-cultural adaptation and validation of the Japanese version of the Childhood Health Assessment Questionnaire (CHAQ)Takako Miyamae
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawaku, Yokohama 236 0004, Japan
Mod Rheumatol 18:336-43. 2008..Functional ability, as assessed by the CHAQ, may not be the main consideration of sJIA patients' parents when assessing their child's status...
[Clinical features and laboratory findings in children with both anti-dsDNA and anti-U1-RNP antibody]Takako Miyamae
Department of Pediatrics, Yokohama City University
Nihon Rinsho Meneki Gakkai Kaishi 31:405-14. 2008....
[Effects of therapies on childhood systemic lupus erythematosus]Rumiko Kurosawa
Department of Pediatrics, Yokohama City University School of Medicine
Ryumachi 43:632-7. 2003..In conclusion, the combination of immunosuppressants and IVCY appeared to offer great benefits in childhood systemic lupus erythematosus...
Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trialShumpei Yokota
Department of Paediatrics, Yokohama City University School of Medicine, Yokohama, Japan
Lancet 371:998-1006. 2008..We investigated the efficacy and safety of tocilizumab, an anti-interleukin-6-receptor monoclonal antibody, in children with this disorder...
Association of HLA-A*02:06 and HLA-DRB1*04:05 with clinical subtypes of juvenile idiopathic arthritisMasakatsu Yanagimachi
Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan
J Hum Genet 56:196-9. 2011..We also found an association between HLA-DRB1(*)04:05 and polyarticular JIA. Thus, clinical subtypes of JIA can be classified by the presence of the specific HLA alleles, HLA-A(*)02:06 and DRB1(*)04:05...
Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritisMasakatsu Yanagimachi
Department of Pediatrics, Yokohama City University Graduate School of Medicine and the CNV Laboratory, DNA Chip Research Institute, Yokohama, Japan
J Rheumatol 38:769-74. 2011..Our aim was to assess associations of IRF5 gene polymorphisms with susceptibility to systemic JIA and MAS...
Improvement of reduced serum cartilage oligomeric matrix protein levels in systemic juvenile idiopathic arthritis patients treated with the anti-interleukin-6 receptor monoclonal antibody tocilizumabShoko Nakajima
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, Kanagawa, 236 0004, Japan
Mod Rheumatol 19:42-6. 2009....
Association of IRF5 polymorphisms with susceptibility to hemophagocytic lymphohistiocytosis in childrenMasakatsu Yanagimachi
Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan
J Clin Immunol 31:946-51. 2011..IRF5 acts as a master transcription factor in the activation of pro-inflammatory cytokines. We assessed associations of IRF5 gene polymorphisms with susceptibility to secondary HLH...
[Cyclophosphamide pulse therapy for pediatric systemic sclerosis]Naomi Iwata
Department of Pediatrics and Dermatology, Yokohama City University School of Medicine, Yokohama, Japan
Ryumachi 43:660-6. 2003..We further observed that their total skin score was decreasing while the clinical manifestations improved...
[Two patients with childhood-onset Behcet's disease successfully treated by anti-tumor necrosis factor therapy]Utako Kaneko
Department of Pediatrics, Yokohama City University School of Medicines, Yokohama, Japan
Nihon Rinsho Meneki Gakkai Kaishi 33:157-61. 2010..A resolution of the systemic and mucocutaneous symptoms was achieved. Furthermore, she was free from corticosteroids in three months. Anti-TNF therapy would be a good choice for juvenile BD refractory to conventional treatments...
[A case report of childhood systemic lupus erythematosus complicated with lupus cystitis]Rumiko Kurosawa
Department of Pediatrics, Yokohama City University School of Medicine
Nihon Rinsho Meneki Gakkai Kaishi 29:154-9. 2006..We reported a case of childhood SLE complicated with lupus cystitis and successfully treated by IVCY-pulse therapy and maintenance predonisolone and azathioprin...
Clinical study of tocilizumab in children with systemic-onset juvenile idiopathic arthritisShumpei Yokota
Department of Pediatrics, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
Clin Rev Allergy Immunol 28:231-8. 2005..A confirmation of the role of tocilizumab in the treatment of sJIA will be provided by the results of the ongoing phase III study in Japan...
The role of heme oxygenase-1 in systemic-onset juvenile idiopathic arthritisAkitaka Takahashi
Department of Pediatrics, Yokohama City University School of Medicine, Kanazawa Ku, Yokohama, Kanagawa, Japan
Mod Rheumatol 19:302-8. 2009..Further study will be necessary to elucidate the mechanism of HO-1 production and to clarify the role of HO-1 in the disease process...
[Infliximab therapy for three adolescent patients with refractory Takayasu's arteritis]Utako Kaneko
Department of Pediatrics, Yokohama City University School of Medicines, Yokohama, Japan
Nihon Rinsho Meneki Gakkai Kaishi 33:317-23. 2010..Infliximab would be a good choice for adolescent patients with TA refractory to conventional treatments. However, we should carefully monitor safety and efficacy of this agent considering its peculiarity...
Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cellsShoko Nakajima
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, Kanagawa 236 0004, Japan
Cytokine 47:91-7. 2009....
Efficacy and limitation of infliximab treatment for children with Kawasaki disease intractable to intravenous immunoglobulin therapy: report of an open-label case seriesMasaaki Mori
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, Kanagawa 236 0004, Japan
J Rheumatol 39:864-7. 2012..Plasma exchange (PE) was available as a rescue therapy for patients refractory to infliximab...
Whole blood interferon-gamma assay for tuberculosis in children in JapanRumiko Higuchi
Department of Pediatrics, Yokohama City University, Yokohama, Kanagawa, Japan
Pediatr Int 51:97-102. 2009..The aim of the present study was to assess the usefulness of QFT-2G as an indicator, both for diagnosing childhood TB and for assessing therapeutic effectiveness...
[Two female siblings with childhood-onset systemic lupus erythematosus]Fumie Sano
Department of Pediatrics, Yokohama City University School of Medicine, Japan
Nihon Rinsho Meneki Gakkai Kaishi 31:172-7. 2008..HLA typing was performed and the siblings were noted to have the same haplotype; A(*)0207, A(*)2402, B(*)4601, B(*)5201, B(*)5201, Cw(*)0102, Cw(*)1202, DRB1(*)0101, DRB1(*)0803...
[Sjögren's syndrome associated with childhood-onset systemic lupus erythematosus]Naomi Iwata
Department of Pediatrics, Yokohama City University, Japan
Nihon Rinsho Meneki Gakkai Kaishi 31:166-71. 2008..The revised criteria is useful for diagnosis of SS in early stage before the development of exocrine gland damage and appears to be helpful for long term follow-up in childhood-onset SLE associated with SS...
Efficacy of plasma exchange therapy for Kawasaki disease intractable to intravenous gamma-globulinMasaaki Mori
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fuku ura, Kanazawa Ku, Yokohama, 236 0004, Japan
Mod Rheumatol 14:43-7. 2004..PE should be performed at an early stage, as soon as fractional increases in inflammatory markers are found after IVGG therapy...
HLA-DRB1*15021 is the predominant allele in Japanese patients with juvenile dermatomyositisNoriaki Tomono
Division of Immunology and Rheumatology, Department of Pediatrics, Yokohama City University School of Medicine, Yokohama, Japan
J Rheumatol 31:1847-50. 2004..To investigate HLA molecules and genes in Japanese patients with juvenile dermatomyositis (JDM)...
Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritisMasakatsu Yanagimachi
Department of Pediatrics, Yokohama City University Graduate School of Medicine, Kanazawa Ku, Yokohama 236 0004, Japan
Br J Clin Pharmacol 71:237-43. 2011..We investigated whether several polymorphisms within the methotrexate (MTX) pathway genes were related to the toxicity and efficacy of MTX in 92 Japanese patients with articular-type juvenile idiopathic arthritis (JIA)...
[Gastrointestinal involvement and renal infarction in a boy with classic polyarteritis nodosa diagnosed with 3D-computed tomography angiography]Fumie Sano
Department of Pediatrics, Yokohama City University
Nihon Rinsho Meneki Gakkai Kaishi 31:415-21. 2008....
Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritisTomoyuki Imagawa
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, Kanagawa, 236 0004, Japan
Mod Rheumatol 22:109-15. 2012..In conclusion, tocilizumab showed early and sustained efficacy and tolerability for treating intractable pJIA, which suggests that it is a promising new treatment for this disease...
Survey of psychological support for bereaved families in JapanShigeru Nishimaki
Department of Pediatrics, Yokohama City University, School of Medicine, Kanagawa, Japan
Pediatr Int 51:626-9. 2009..The aim of the present study was to investigate the current conditions of psychological support for the families of children who died suddenly of disease or accident...
Plasma exchange for refractory Kawasaki diseaseTomoyuki Imagawa
Department of Paediatrics, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, 236-0004 Yokohama, Japan
Eur J Pediatr 163:263-4. 2004
Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritisShumpei Yokota
Yokohama City University School of Medicine, Kanagawa, Japan
Arthritis Rheum 52:818-25. 2005....
[Infliximab for a girl with refractory pyoderma gangrenosum]Tomo Nozawa
Department of Pediatrics, Yokohama City University
Nihon Rinsho Meneki Gakkai Kaishi 31:454-9. 2008..The dramatical improvement suggested that infliximab should be considered for patients with refractory pyoderma gangrenosum though further experiences and investigations are required to determine the mechanism of infliximab...
Inflammatory cytokines and systemic-onset juvenile idiopathic arthritisShumpei Yokota
Department of Pediatrics, Yokohama City University School of Medicines, 3 9 Fukuura, Kanazawa Ku, Yokohama, 236 0004, Japan
Mod Rheumatol 14:12-7. 2004..MRA could be a therapeutic modality for children with systemic-onset JIA intractable to high-dose corticosteroids...
[Intravenous cyclophosphamide pulse therapy for refractory juvenile dermatomyositis]Shoko Nakashima
Department of Pediatrics, Yokohama City University, Fukuura, Kanazawa-ku, Yokohama-city
Ryumachi 42:895-902. 2002..In addition, determination of ESR and FDP-E was not specific but helpful to detect flares of the disease in some cases...
De novo 19q13.42 duplications involving NLRP gene cluster in a patient with systemic-onset juvenile idiopathic arthritisHiromi Tadaki
Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Japan
J Hum Genet 56:343-7. 2011..The duplications encompass NLRP family (NLRP2, NLRP9 and NLRP11) as well as IL11 and HSPBP1, all of which have an important role in inflammatory pathways. These genes may significantly contribute to the pathogenesis of s-JIA...
Hyper-IgD syndrome with novel mutation in a Japanese girlTakuya Naruto
Department of Pediatrics, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama, Kanagawa, 236 0004, Japan
Mod Rheumatol 19:96-9. 2009..This is the first case in which homozygosity for the mutation of the MVK gene has been reported in an Asian patient, and indicated a need for differentiation...
National survey of childhood febrile illness cases with fever of unknown origin in JapanKazuko Kasai
Department of Pediatrics, Yokohama City University, Japan
Pediatr Int 53:421-5. 2011..We carried out a national survey on childhood febrile illnesses in order to collect useful information for the differential diagnosis...
[An approach to the patients with cryopyrin-associated periodic syndrome (CAPS) : a new biologic response modifier, canakinumab]Shumpei Yokota
Department of Pediatrics, Yokohama City University School of Medicine
Nihon Rinsho Meneki Gakkai Kaishi 35:23-9. 2012..For us pediatrician, it will be important to be more careful for infectious diseases to provide the maximum safety of canakinumab for these patients...
[Neonatal herpes simplex type II virus infection complicated with meningitis and virus-associated hemophagocytic syndrome]Chie Arai
Department of Pediatrics, Yokohama City University School of Medicine
Nihon Rinsho Meneki Gakkai Kaishi 35:87-91. 2012..Our case report suggests that not only antiviral treatment for HSV, but also anti-inflammatory treatment including steroid and cyclosporine should be considered from the early phase of neonatal systemic HSV infection...
[Multi-center analysis of calcinosis in children with juvenile dermatomyositis]Takako Miyamae
Department of Pediatrics, Yokohama City University, Fukuura, Kanazawa-ku, Yokohama-city
Ryumachi 43:538-43. 2003..Thus, juvenile dermatomyositis is frequently complicated with calcinosis. This type of calcinosis was found to be unlikely to resolve completely, and resulted in severe disability in children...
[A case of classical polyarteritis nodosa diagnosed by myocardial biopsy]Takako Miyamae
Department of Pediatrics, Yokohama City University School of Medicine
Nihon Rinsho Meneki Gakkai Kaishi 25:184-90. 2002..Coronary angiography revealed no abnormalities. The combination therapy of cyclophosphamide pulses and plasma-exchange was very effective to suppress the disease activity...
Mizoribine as an effective combined maintenance therapy with prednisolone in child-onset systemic lupus erythematosusYukoh Aihara
Department of Pediatrics, Yokohama City University Medical Center, Yokohama, Japan
Pediatr Int 44:199-204. 2002..Therefore, we have been attempting to improve the maintenance therapy of child-onset SLE...
