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Genomes and Genes | Masaru NonakaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Publications
Trans-species polymorphism of the major histocompatibility complex-encoded proteasome subunit LMP7 in an amphibian genus, XenopusM Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan
Immunogenetics 51:186-92. 2000..A similar mode of evolution of the LMP7 alleles in Xenopus provides a possible explanation for the linkage of the LMP7 gene with the MHC in all vertebrates analyzed to date...- Complement system of bony and cartilaginous fishM Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan
Fish Shellfish Immunol 10:215-28. 2000..The complement system seems to play a more pivotal role in body defence in fish, whose adaptive immunity is considered to be at a relatively undeveloped state... - Evolution of the complement systemM Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Tokyo 113 0033, Japan
Curr Opin Immunol 13:69-73. 2001..The primitive complement system of these animals is one of the most highly organized innate immune systems... - Opsonic complement system of the solitary ascidian, Halocynthia roretziM Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan
Dev Comp Immunol 23:421-7. 1999..These results indicate that the lectin-dependent, opsonic complement system was present prior to the emergence of the vertebrates and well ahead of the establishment of adaptive immunity... - Molecular genetics of the complement C3 convertases in lower vertebratesM Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan
Immunol Rev 166:59-65. 1998..Genetic linkage between these two family genes within the MHC was observed in Xenopus but not in medaka fish... - Opsonic complement component C3 in the solitary ascidian, Halocynthia roretziM Nonaka
Department of Biochemistry, Nagoya City University Medical School, Japan
J Immunol 162:387-91. 1999.... - Urochordate immunityMasaru Nonaka
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Hongo, Tokyo, Japan
Adv Exp Med Biol 708:302-10. 2010..In contrast, the allorecognition systems of urochordates show no evolutionary relationship with any invertebrate or vertebrate systems, suggesting that they were invented in the urochordate lineage... - Novel androgen-dependent promoters direct expression of the C4b-binding protein alpha-chain gene in epididymisM I Nonaka
Department of Biological Sciences, University of Tokyo, Tokyo, Japan
J Immunol 166:4570-7. 2001..Furthermore, variation in the 5'-untranslated regions, arising from alternative splicing of the newly identified exons, is demonstrable in the guinea pig C4BP alpha transcripts... - Evolution of the initiating enzymes of the complement systemMasaru Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Tokyo 113 0033, Japan
Genome Biol 3:REVIEWS1001. 2002..Phylogenetic studies indicate that one arose by retrotransposition early in vertebrate evolution, supporting the idea that the lectin branch of the complement cascade arose earlier than the 'classical' pathway... - Genomic view of the evolution of the complement systemMasaru Nonaka
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Tokyo, Japan
Immunogenetics 58:701-13. 2006.... - Primitive complement system of invertebratesMasaru Nonaka
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan
Immunol Rev 198:203-15. 2004..Thus, another integrative step seems to have been required to establish the modern complement system of higher vertebrates... - Evolution of the complement systemMasaru Nonaka
Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Tokyo 113 0033, Japan
Mol Immunol 40:897-902. 2004..Thus, the vertebrate complement system seems to be established by integrating some independent parts into one reaction system... - Urochordate immunityMasaru Nonaka
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Hongo, Tokyo, Japan
Adv Exp Med Biol 708:302-10. 2011..In contrast, the allorecognition systems of urochordates show no evolutionary relationship with any invertebrate or vertebrate systems, suggesting that they were invented in the urochordate lineage... - Origin of mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 involved in the lectin complement pathway traced back to the invertebrate, amphioxusYuichi Endo
Department of Biochemistry, Fukushima Medical University School of Medicine, Fukushima, Japan
J Immunol 170:4701-7. 2003..The ancient origin of MASP-1 and MASP-3 suggests that they have crucial functions common to all species which emerged after cephalochordates... - Structure and the evolutionary implication of the triplicated complement factor B genes of a urochordate ascidian, Ciona intestinalisFumiko Y Yoshizaki
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113 0033, Japan
Immunogenetics 56:930-42. 2005.... - Unprecedented intraspecific diversity of the MHC class I region of a teleost medaka, Oryzias latipesKentaro Tsukamoto
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan
Immunogenetics 57:420-31. 2005.... - Characterization of novel ascidian beta integrins as primitive complement receptor subunitsSeita Miyazawa
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Tokyo, Japan
Immunogenetics 55:836-44. 2004.... - Molecular cloning of the terminal complement components C6 and C8beta of cartilaginous fishAyuko Kimura
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Fish Shellfish Immunol 27:768-72. 2009..These results also indicate that the gene duplications among TCCs occurred at an early stage of the jawed vertebrate evolution... - Transspecies dimorphic allelic lineages of the proteasome subunit beta-type 8 gene (PSMB8) in the teleost genus OryziasFumi Miura
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo 113 0033, Japan
Proc Natl Acad Sci U S A 107:21599-604. 2010.... - Multi-component complement system of Cnidaria: C3, Bf, and MASP genes expressed in the endodermal tissues of a sea anemone, Nematostella vectensisAyuko Kimura
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Immunobiology 214:165-78. 2009.... - Evolutionary analysis of two classical MHC class I loci of the medaka fish, Oryzias latipes: haplotype-specific genomic diversity, locus-specific polymorphisms, and interlocus homogenizationMayumi I Nonaka
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo, 113 0033, Japan
Immunogenetics 62:319-32. 2010..Two lineages of the transmembrane and cytoplasmic regions are also shared by UAA and UBA, suggesting that these two loci evolved with intimate genetic interaction through gene conversion or unequal crossing over... - Evolution of thioester-containing proteins revealed by cloning and characterization of their genes from a cnidarian sea anemone, Haliplanella lineateNaoko T Fujito
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyoku, Tokyo, Japan
Dev Comp Immunol 34:775-84. 2010..These results suggest that gene duplication and subsequent functional differentiation among C3, A2M and CD109 were very ancient events predating the divergence of the cnidaria and bilateria... - Evolution of proteasome subunits delta and LMP2: complementary DNA cloning and linkage analysis with MHC in lower vertebratesM Nonaka
Department of Biochemistry, Nagoya City University Medical School, Mizuho ku, Japan
J Immunol 159:734-40. 1997..Sequence and linkage analyses suggest that LMP2 may not play as vital a role as LMP7 in Ag presentation... - Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebratesY Endo
Department of Biochemistry, Fukushima Medical College, Japan
J Immunol 161:4924-30. 1998..Furthermore, the presence of MASP or MASP-like sequences in most vertebrate species suggests that the lectin pathway functions extensively in vertebrates and that its origin is traced back to the invertebrate stage... - Dichotomous haplotypic lineages of the immunoproteasome subunit genes, PSMB8 and PSMB10, in the MHC class I region of a Teleost Medaka, Oryzias latipesKentaro Tsukamoto
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan
Mol Biol Evol 26:769-81. 2009..These results indicate that the two medaka MHC haplotypic lineages encompassing the PSMB8 and PSMB10 genes are maintained in wild populations by a balancing selection... - Isolation of the Xenopus complement factor B complementary DNA and linkage of the gene to the frog MHCY Kato
Department of Biochemistry, Nagoya City University Medical School, Japan
J Immunol 153:4546-54. 1994.... - Isolation of Xenopus LMP-7 homologues. Striking allelic diversity and linkage to MHCC Namikawa
Department of Biochemistry, Nagoya City University Medical School, Japan
J Immunol 155:1964-71. 1995..The great allelic diversity can be explained either by coselection with particular class I alleles or by differential silencing of MHC genes in the polyploid X. laevis... - Molecular cloning and linkage analysis of complement C3 and C4 genes of the Japanese medaka fishN Kuroda
Department of Biochemistry, Nagoya City University Medical School, Nagoya, Japan
Immunogenetics 51:117-28. 2000..These results suggest that the MHC class III complement region was established in the tetrapod lineage, or lost in the teleost lineage... - Evolutionary origin of the vertebrate blood complement and coagulation systems inferred from liver EST analysis of lampreyAyuko Kimura
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Dev Comp Immunol 33:77-87. 2009.... - Complement C4b-binding protein as a novel murine epididymal secretory proteinMayumi I Nonaka
Department of Biological Sciences, University of Tokyo, Tokyo 133 0033, Japan
Biol Reprod 69:1931-9. 2003..Our findings suggest a novel function of C4BP as one such epididymal secretory protein... - Expression patterns of Hox genes in larvae of the sea lily Metacrinus rotundusYuko Hara
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan
Dev Genes Evol 216:797-809. 2006..Our study illuminates the possible body plan and Hox expression patterns of the ancestral echinoderm and sheds light on the larval body plan of the last common ancestor of the echinoderms and chordates... - Primitive complement system--recognition and activationTeizo Fujita
Department of Biochemistry, Fukushima Medical University, and CREST, Japan Science and Technology Agency, Japan
Mol Immunol 41:103-11. 2004..Thus, another integrative step seems to have been required to establish the modern complement system of higher vertebrates... - Genetic linkage between the LMP2 and LMP7 genes in the medaka fish, a teleostC Namikawa-Yamada
Department of Biochemistry, Nagoya City University Medical School, Mizuho-ku, Nagoya 467, Japan
Immunogenetics 46:431-3. 1997 - Retained orthologous relationships of the MHC Class I genes during euteleost evolutionMayumi I Nonaka
Department of Biological Sciences, The University of Tokyo, Tokyo, Japan
Mol Biol Evol 28:3099-112. 2011..Such evolutionary mode is characteristic to the teleost MHC class I genes and might have contributed to the long-term conservation of the ?1 domain... - Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: "waiting for Godot"Kaoru Azumi
Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan
Immunogenetics 55:570-81. 2003..However, there are key V regions, the essential feature of an immunoglobulin superfamily VC1-like core, and possible proto-MHC regions scattered throughout the genome waiting for Godot... - Comparative genomic analysis of the major histocompatibility complex class I region in the teleost genus OryziasRatnesh Bhai Mehta
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo ku, Tokyo, Japan
Immunogenetics 61:385-99. 2009..Thus, the three independent evolutionary patterns under apparently distinctive selective pressures are recognized in the Oryzias MHC class I region... - Molecular cloning and linkage analysis of the Japanese medaka fish complement Bf/C2 geneN Kuroda
Department of Biochemistry, Nagoya City University Medical School, Mizuho ku, Nagoya 467, Japan
Immunogenetics 44:459-67. 1996..The Bf/C2 locus was mapped to the close proximity (2.9 cM) of the superoxide dismutase locus on the linkage group XX by the use of a restriction site polymorphism between two inbred strains of the medaka... - Cloning and characterization of integrin alpha subunits from the solitary ascidian, Halocynthia roretziS Miyazawa
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo, Japan
J Immunol 166:1710-5. 2001..roretzi that functions as an ancestral form of CR3 and CR4 and mediates phagocytosis in the primitive complement system of the ascidian... - A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distributionN Hamajima
Department of Pediatrics, Nagoya City University Medical School, Japan
Gene 180:157-63. 1996..e., human DHPase, in liver and kidney; human DRP-1, in brain; human DRP-2, ubiquitously expressed except for liver; human DRP-3, mainly in heart and skeletal muscle... - Repetitive elements in the major histocompatibility complex (MHC) class I region of a teleost, medaka: identification of novel transposable elementsMegumi Y Matsuo
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Mech Dev 121:771-7. 2004..Since eight of the 11 transposable elements were located in this region, these elements may have played a role in the medaka-specific DNA rearrangement... - A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolutionK Naruse
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Bunkyo ku, Tokyo 113 0033, Japan
Genetics 154:1773-84. 2000..Unlike zebrafish, however, the Medaka linkage map showed obvious restriction of recombination on the linkage group containing the male-determining region (Y) locus compared to the autosomal chromosomes... - Duplication of the MHC-linked Xenopus complement factor B geneY Kato
Department of Biochemistry, Nagoya City University Medical School, Japan
Immunogenetics 42:196-203. 1995.... - C6-like and C3-like molecules from the cephalochordate, amphioxus, suggest a cytolytic complement system in invertebratesMiho M Suzuki
Department of Zoology, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan
J Mol Evol 54:671-9. 2002..Only opsonic activity has been assigned to the invertebrate complement system until now. Therefore, this is the first molecular evidence for complement-mediated immunological cytotoxicity in invertebrates... - Nucleotide sequence of the MHC class I genomic region of a teleost, the medaka (Oryzias latipes)Megumi Y Matsuo
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Immunogenetics 53:930-40. 2002..These results suggest that a strong selective pressure has conserved the linkage of certain MHC genes during vertebrate evolution, despite recurrent genetic rearrangements... - Molecular heterotopy in the expression of Brachyury orthologs in order Clypeasteroida (irregular sea urchins) and order Echinoida (regular sea urchins)Taku Hibino
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Tokyo, 113-0033, Japan
Dev Genes Evol 214:546-58. 2004..In the Echinoida species, Bra was expressed in the vestibule at the six-armed pluteus stage... - Complement-related serine proteases in tunicates and vertebratesM Matsushita
Department of Biochemistry, Fukushima Medical College, Japan
Curr Opin Immunol 10:29-35. 1998..MASP, C1r and C1s belong to the same family of serine proteases. In addition to its presence in advanced species, MASP also exists in primitive life forms such as tunicates and may be an evolutionary prototype of this family... - Highly divergent dimorphic alleles of the proteasome subunit beta type-8 (PSMB8) gene of the bichir Polypterus senegalus: implication for evolution of the PSMB8 gene of jawed vertebratesNaoko T Fujito
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
Immunogenetics 64:447-53. 2012..However, phylogenetic analysis showed that the dimorphisms of PSMB8 of bichir, Xenopus, and Oryzias arose by independent evolutionary events, suggesting the presence of a strong selective pressure for possessing the dimorphism... - Evolution of the thioester-containing proteins (TEPs) of the arthropoda, revealed by molecular cloning of TEP genes from a spider, Hasarius adansoniReo Sekiguchi
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113 0033, Japan
Dev Comp Immunol 36:483-9. 2012..These results suggest that the common ancestor of the Arthropoda possessed at least three TEP genes, C3, A2M and iTEP and that they were lost differentially in the Crustacean and Hexapodan lineages... - Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous systemH Inagaki
Department of Pathology, Nagoya City University Medical School, Mizuho ku, Nagoya 467 8601, Japan
Histochem Cell Biol 113:37-41. 2000..Northern blot analysis showed that DRPs were differentially expressed in the mouse and human intestines, supporting the results of ISH. These data suggest that DRPs play a role not only in the CNS but also in the ENS... - Identification of novel mutations in the dihydropyrimidine dehydrogenase gene in a Japanese patient with 5-fluorouracil toxicityM Kouwaki
Department of Pediatrics, Nagoya City University Medical School, Nagoya, Japan
Clin Cancer Res 4:2999-3004. 1998..The present data represent the first molecular genetic analysis of DPD deficiency accompanied by severe 5-FU toxicity in a Japanese patient... - Dihydropyrimidinase deficiency: structural organization, chromosomal localization, and mutation analysis of the human dihydropyrimidinase geneN Hamajima
Department of Pediatrics, Nagoya City University Medical School, Nagoya City Higashi General Hospital, Nagoya, Japan
Am J Hum Genet 63:717-26. 1998..There was no significant difference, in residual activity, between mutations observed in the symptomatic and those observed in the asymptomatic individuals... - Characterization of the human dihydropyrimidinase-related protein 2 (DRP-2) geneK Kitamura
Department of Biochemistry, Nagoya City University Medical School, Nagoya, Japan
DNA Res 6:291-7. 1999.... - Autoantibody to gravin is expressed more strongly in younger and nonthymomatous patients with myasthenia gravisH Sasaki
Department of Surgery II, Nagoya City University Medical School, Nagoya, Japan
Surg Today 31:1036-7. 2001..These findings suggest that antigravin antibody activities could be a useful prognostic factor and that the gravin antibody of MG may have a function which prevents the protein A-kinase binding pathway... - Distinct expression of RANTES and GM-CSF by lipopolysaccharide in human nasal fibroblasts but not in other airway fibroblastsM Nonaka
Department of Otorhinolaryngology, Nippon Medical School, Tokyo, Japan
Int Arch Allergy Immunol 119:314-21. 1999..These findings suggest that nasal fibroblasts may play an important role in the recruitment and activation of eosinophils into nasal polyps through the release of RANTES and GM-CSF... - Organ perfusion combined with platelet aggregation inhibitor reduce IgM deposition and hyperacute xenorejection in a guinea pig-to-rat lung transplantation modelM Nonaka
First Department of Surgery, Showa University School of Medicine, Tokyo, Japan
Transplant Proc 34:2749-51. 2002 - Induction of eotaxin production by interleukin-4, interleukin-13 and lipopolysaccharide by nasal fibroblastsM Nonaka
Department of Otorhinolaryngology, Nippon Medical School, Tokyo, Japan
Clin Exp Allergy 34:804-11. 2004.... - Conservation of the modular structure of complement factor I through vertebrate evolutionTokio Terado
Department of Experimental Radiology, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan
Dev Comp Immunol 26:403-13. 2002.... - Ancestral organization of the MHC revealed in the amphibian XenopusYuko Ohta
Department of Microbiology and Immunology, University of Maryland, 655 West Baltimore Street, BRB13 009, Baltimore, MD 21201, USA
J Immunol 176:3674-85. 2006..Thus, the amphibian MHC is the most evolutionary conserved MHC so far analyzed... - Molecular cloning of C4 gene and identification of the class III complement region in the shark MHCTokio Terado
Department of Experimental Radiology, Shiga University of Medical Science, Ohtsu-shi, Shiga, Japan
J Immunol 171:2461-6. 2003.... - Two highly divergent ancient allelic lineages of the transporter associated with antigen processing (TAP) gene in Xenopus: further evidence for co-evolution among MHC class I region genesYuko Ohta
Department of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, USA
Eur J Immunol 33:3017-27. 2003..Furthermore, like the LMP7 lineages, the TAP lineages were detected in most Xenopus species that diverged from a common ancestor 80-100 MYA, suggesting that the 'class I region' biallelic lineages are under balancing selection... - The draft genome of Ciona intestinalis: insights into chordate and vertebrate originsParamvir Dehal
U.S. Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
Science 298:2157-67. 2002..The ascidian genome has also acquired a number of lineage-specific innovations, including a group of genes engaged in cellulose metabolism that are related to those in bacteria and fungi... - The amphioxus genome illuminates vertebrate origins and cephalochordate biologyLinda Z Holland
Marine Biology Research Division, Scripps Institution of Oceanography, La Jolla, California 92093 0202, USA
Genome Res 18:1100-11. 2008..Our results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates... - A three-step proteolytic cascade mediates the activation of the peptidoglycan-induced toll pathway in an insectChan Hee Kim
National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609 735, Korea
J Biol Chem 283:7599-607. 2008..These results demonstrate that the three-step proteolytic cascade linking the PG recognition complex and Spätzle processing is essential for the PG-dependent Toll signaling pathway... - Gene expression profile during the life cycle of the urochordate Ciona intestinalisKaoru Azumi
Division of Innovative Research, Creative Research Initiative Sousei, Hokkaido University, N21W10 Kita ku, Sapporo 001 0021, Japan
Dev Biol 308:572-82. 2007..This large-scale oligo-DNA microarray for C. intestinalis should facilitate the understanding of global gene expression and gene networks during the development and aging of a basal chordate... - Hemocytes of Ciona intestinalis express multiple genes involved in innate immune host defenseKazuhito Shida
Center for Interdisciplinary Research, Tohoku University, Sendai, Japan
Biochem Biophys Res Commun 302:207-18. 2003..As expected, elements of acquired immunity were not detected. Thus, Ciona hemocytes appear to express a number of host defense-related genes involved in innate immune mechanisms... - Identification of transcripts expressed preferentially in hemocytes of Ciona intestinalis that can be used as molecular markersTakeshi Wakoh
Institute of Development, Aging, and Cancer, Tohoku University, Seiryo-machi, 4-1, Aoba-ku, Sendai 980-8575, Japan
DNA Res 11:345-52. 2004..We propose that vWA-like and C6-like can be used as molecular markers for Ciona hemocytes... - Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI)Manfred Schartl
Biocenter, University of Wuerzburg, Am Hubland, D-97074 Wuerzburg, Germany
Methods Cell Biol 77:173-99. 2004 - A short consensus repeat-containing complement regulatory protein of lamprey that participates in cleavage of lamprey complement 3Yuko Kimura
Department of Immunology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
J Immunol 173:1118-28. 2004..We named this protein Lacrep, the lamprey C regulatory protein. Lacrep is a member of SCR-containing C regulators, the first of its kind identified in the lowest vertebrates... - The DNA sequence of medaka chromosome LG22Takashi Sasaki
Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Tokyo 160 8582, Japan
Genomics 89:124-33. 2007..These precise comparative genomics allowed us to identify the pieces of ancient chromosomes of the common vertebrate ancestor and estimate chromosomal evolution in the vertebrate lineage...